Uncovering the global host cell requirements for influenza virus replication via RNAi screening.
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Functional genomic and high-content screening for target discovery and deconvolutionHistone deacetylase 8 is required for centrosome cohesion and influenza A virus entryThe Influenza Virus Polymerase Complex: An Update on Its Structure, Functions, and Significance for Antiviral Drug DesignThe interactomes of influenza virus NS1 and NS2 proteins identify new host factors and provide insights for ADAR1 playing a supportive role in virus replicationHigh-content analysis of sequential events during the early phase of influenza A virus infectionChemical Genomics Identifies the PERK-Mediated Unfolded Protein Stress Response as a Cellular Target for Influenza Virus InhibitionInhibitory and combinatorial effect of diphyllin, a v-ATPase blocker, on influenza viruses.Newer influenza antivirals, biotherapeutics and combinations.Meta- and Orthogonal Integration of Influenza "OMICs" Data Defines a Role for UBR4 in Virus Budding.Prioritizing genes responsible for host resistance to influenza using network approachesSystems virology: host-directed approaches to viral pathogenesis and drug targeting.Recruitment of RED-SMU1 complex by Influenza A Virus RNA polymerase to control Viral mRNA splicingA genome wide RNA interference screening method to identify host factors that modulate influenza A virus replication.Prolidase is required for early trafficking events during influenza A virus entryLimited agreement of independent RNAi screens for virus-required host genes owes more to false-negative than false-positive factors.Differential host response, rather than early viral replication efficiency, correlates with pathogenicity caused by influenza viruses.A comprehensive map of the influenza A virus replication cycleSimultaneous analysis of large-scale RNAi screens for pathogen entry.Variations in genome-wide RNAi screens: lessons from influenza research.Genome-wide analysis of host factors in nodavirus RNA replication.Systems-biology approaches to discover anti-viral effectors of the human innate immune response.Cathepsin W Is Required for Escape of Influenza A Virus from Late Endosomes.RNAseq expression analysis of resistant and susceptible mice after influenza A virus infection identifies novel genes associated with virus replication and important for host resistance to infectionCell-based genomic screening: elucidating virus-host interactionsTRIM22 inhibits influenza A virus infection by targeting the viral nucleoprotein for degradation.Identifying proteins controlling key disease signaling pathwaysExploration of binary virus-host interactions using an infectious protein complementation assayMoving H5N1 studies into the era of systems biology.Acid phosphatase 2 (ACP2) is required for membrane fusion during influenza virus entry.Influenza virus-host interactomes as a basis for antiviral drug development.FAT10 Is Critical in Influenza A Virus Replication by Inhibiting Type I IFN.Role of Host Genes in Influenza Virus Replication.Identification of Polo-like kinases as potential novel drug targets for influenza A virus.A CRISPR Activation Screen Identifies a Pan-avian Influenza Virus Inhibitory Host Factor.Influenza A virus nucleoprotein targets subnuclear structures.Cellular fatty acid synthase is required for late stages of HIV-1 replication.Active Learning Strategies for Phenotypic Profiling of High-Content Screens.Nanoparticulate vacuolar ATPase blocker exhibits potent host-targeted antiviral activity against feline coronavirus.A Bird's Eye View of Influenza A Virus Transmission: Challenges with Characterizing Both Sides of a Co-Evolutionary Dynamic.Genetic screens for the control of influenza virus replication: from meta-analysis to drug discovery.
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P2860
Uncovering the global host cell requirements for influenza virus replication via RNAi screening.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 27 January 2011
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Uncovering the global host cel ...... eplication via RNAi screening.
@en
Uncovering the global host cel ...... eplication via RNAi screening.
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type
label
Uncovering the global host cel ...... eplication via RNAi screening.
@en
Uncovering the global host cel ...... eplication via RNAi screening.
@nl
prefLabel
Uncovering the global host cel ...... eplication via RNAi screening.
@en
Uncovering the global host cel ...... eplication via RNAi screening.
@nl
P2860
P1476
Uncovering the global host cel ...... replication via RNAi screening
@en
P2093
Megan L Shaw
Silke Stertz
P2860
P304
P356
10.1016/J.MICINF.2011.01.012
P577
2011-01-27T00:00:00Z