about
Independent introduction of two lactase-persistence alleles into human populations reflects different history of adaptation to milk cultureTranscriptional control of steroid biosynthesis genes in the Drosophila prothoracic gland by ventral veins lacking and knirpsAn upstream polymorphism associated with lactase persistence has increased enhancer activityAdult-type hypolactasia and regulation of lactase expressionBlue eye color in humans may be caused by a perfectly associated founder mutation in a regulatory element located within the HERC2 gene inhibiting OCA2 expressionInvolvement of activator protein 1 complexes in the epithelium-specific activation of the laminin γ2-chain gene promoter by hepatocyte growth factor (scatter factor)Carriers of a VEGFA enhancer polymorphism selectively binding CHOP/DDIT3 are predisposed to increased circulating levels of thyroid-stimulating hormoneDiagnosis of ulcerative colitis before onset of inflammation by multivariate modeling of genome-wide gene expression data.Mapping of HNF4alpha target genes in intestinal epithelial cellsDifferences in inflammation and acute phase response but similar genotoxicity in mice following pulmonary exposure to graphene oxide and reduced graphene oxide.pcaGoPromoter--an R package for biological and regulatory interpretation of principal components in genome-wide gene expression dataPreaxial polydactyly/triphalangeal thumb is associated with changed transcription factor-binding affinity in a family with a novel point mutation in the long-range cis-regulatory element ZRSDifferentiation-dependent activation of the human intestinal alkaline phosphatase promoter by HNF-4 in intestinal cells.Identification of TNF-α-responsive promoters and enhancers in the intestinal epithelial cell model Caco-2.HOXB4 Gene Expression Is Regulated by CDX2 in Intestinal Epithelial Cells.Diversity of lactase persistence alleles in Ethiopia: signature of a soft selective sweep.Mitogen activated protein kinases: a role in inflammatory bowel disease?The role of CDX2 in intestinal homeostasis and inflammation.Current and emerging approaches to define intestinal epithelium-specific transcriptional networks.The clinical perspectives of CDX2 expression in colorectal cancer: a qualitative systematic review.Two intestinal specific nuclear factors binding to the lactase-phlorizin hydrolase and sucrase-isomaltase promoters are functionally related oligomeric molecules.The -14010*C variant associated with lactase persistence is located between an Oct-1 and HNF1α binding site and increases lactase promoter activity.Clinical implications of intestinal stem cell markers in colorectal cancer.Cellular inhibitor of apoptosis protein 2 controls human colonic epithelial restitution, migration, and Rac1 activation.Involvement of CDX2 in the cross talk between TNF-α and Wnt signaling pathway in the colon cancer cell line Caco-2.Regulation of APC and AXIN2 expression by intestinal tumor suppressor CDX2 in colon cancer cells.TNF-α-induced down-regulation of CDX2 suppresses MEP1A expression in colitis.Regulation of Laminin γ2 Expression by CDX2 in Colonic Epithelial Cells Is Impaired During Active Inflammation.Control of intestinal promoter activity of the cellular migratory regulator gene ELMO3 by CDX2 and SP1.The prognostic value of polycomb group protein B-cell-specific moloney murine leukemia virus insertion site 1 in stage II colon cancer patients.HNF1 alpha activates the aminopeptidase N promoter in intestinal (Caco-2) cells.Precise integration of inducible transcriptional elements (PrIITE) enables absolute control of gene expression.Mathematical modelling as a proof of concept for MPNs as a human inflammation model for cancer developmentIn Vitro Functional Analyses of Infrequent Nucleotide Variants in the Lactase Enhancer Reveal Different Molecular Routes to Increased Lactase Promoter Activity and Lactase PersistenceGenome-wide analysis of CDX2 binding in intestinal epithelial cells (Caco-2)Converging signals synergistically activate the LAMC2 promoter and lead to accumulation of the laminin gamma 2 chain in human colon carcinoma cells.An enhancer activates the pig lactase phlorizin hydrolase promoter in intestinal cells.[Lactose intolerance. Genotyping simplifies and improves diagnosis].Cellular cross talk in the small intestinal mucosa: postnatal lymphocytic immigration elicits a specific epithelial transcriptional response.T-13910 DNA variant associated with lactase persistence interacts with Oct-1 and stimulates lactase promoter activity in vitro.
P50
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Jesper Thorvald Troelsen
@ast
Jesper Thorvald Troelsen
@en
Jesper Thorvald Troelsen
@es
Jesper Thorvald Troelsen
@nl
Jesper Thorvald Troelsen
@sl
type
label
Jesper Thorvald Troelsen
@ast
Jesper Thorvald Troelsen
@en
Jesper Thorvald Troelsen
@es
Jesper Thorvald Troelsen
@nl
Jesper Thorvald Troelsen
@sl
prefLabel
Jesper Thorvald Troelsen
@ast
Jesper Thorvald Troelsen
@en
Jesper Thorvald Troelsen
@es
Jesper Thorvald Troelsen
@nl
Jesper Thorvald Troelsen
@sl
P1053
B-6264-2013
P106
P1153
6603893960
P21
P31
P3829
P496
0000-0002-4177-3267