about
Chk1 and p21 cooperate to prevent apoptosis during DNA replication fork stressOsteosarcoma: Cells-of-Origin, Cancer Stem Cells, and Targeted TherapiesIsolation and characterization of nudC from mouse macrophages, a gene implicated in the inflammatory response through the regulation of PAF-AH(I) activityApoptosis induced by replication inhibitors in Chk1-depleted cells is dependent upon the helicase cofactor Cdc45.ATR and Chk1 suppress a caspase-3-dependent apoptotic response following DNA replication stress.DNA replication stress in CHK1-depleted tumour cells triggers premature (S-phase) mitosis through inappropriate activation of Aurora kinase B.Loss of p53 induces tumorigenesis in p21-deficient mesenchymal stem cellsMesenchymal stem cells and their use as cell replacement therapy and disease modelling tool.Insights into the cellular origin and etiology of the infant pro-B acute lymphoblastic leukemia with MLL-AF4 rearrangement.Modeling sarcomagenesis using multipotent mesenchymal stem cells.FUS-CHOP fusion protein expression coupled to p53 deficiency induces liposarcoma in mouse but not in human adipose-derived mesenchymal stem/stromal cells.Bone microenvironment signals in osteosarcoma development.Human bone marrow stromal cells lose immunosuppressive and anti-inflammatory properties upon oncogenic transformation.Bone environment is essential for osteosarcoma development from transformed mesenchymal stem cells.Expression of FUS-CHOP fusion protein in immortalized/transformed human mesenchymal stem cells drives mixoid liposarcoma formation.Enrichment of human ESC-derived multipotent mesenchymal stem cells with immunosuppressive and anti-inflammatory properties capable to protect against experimental inflammatory bowel disease.Thymidine selectively enhances growth suppressive effects of camptothecin/irinotecan in MSI+ cells and tumors containing a mutation of MRE11.Effect of vinca alkaloids on ERalpha levels and estradiol-induced responses in MCF-7 cells.Polyinosinic acid induces TNF and NO production as well as NF-kappaB and AP-1 transcriptional activation in the monocytemacrophage cell line RAW 264.7.Bone marrow mesenchymal stem cells from infants with MLL-AF4+ acute leukemia harbor and express the MLL-AF4 fusion geneTNF triggers mitogenic signals in NIH 3T3 cells but induces apoptosis when the cell cycle is blocked.The globoseries glycosphingolipid SSEA-4 is a marker of bone marrow-derived clonal multipotent stromal cells in vitro and in vivo.FUS-CHOP Promotes Invasion in Myxoid Liposarcoma through a SRC/FAK/RHO/ROCK-Dependent Pathway.The mouse tumor necrosis factor receptor 2 gene: genomic structure and characterization of the two transcripts.The differentiation stage of p53-Rb-deficient bone marrow mesenchymal stem cells imposes the phenotype of in vivo sarcoma development.Circulating cancer cells in division in an early breast cancer patient.Deficiency in p53 but not retinoblastoma induces the transformation of mesenchymal stem cells in vitro and initiates leiomyosarcoma in vivo.Role of Activator Protein-1 Complex on the Phenotype of Human Osteosarcomas Generated from Mesenchymal Stem CellsDistinctive Expression and Amplification of Genes at 11q13 in Relation to HPV Status with Impact on Survival in Head and Neck Cancer PatientsThe Novel Role of SOX2 as an Early Predictor of Cancer Risk in Patients with Laryngeal Precancerous LesionsMultipotent mesenchymal stromal cells: clinical applications and cancer modelingInactivation of p53 in Human Keratinocytes Leads to Squamous Differentiation and Shedding via Replication Stress and Mitotic SlippageSarcoma Stem Cell HeterogeneityThe multikinase inhibitor EC-70124 synergistically increased the antitumor activity of doxorubicin in sarcomasThe Differential Impact of SRC Expression on the Prognosis of Patients with Head and Neck Squamous Cell CarcinomaSOX2 Expression and Transcriptional Activity Identifies a Subpopulation of Cancer Stem Cells in Sarcoma with Prognostic ImplicationsThe SRC Inhibitor Dasatinib Induces Stem Cell-Like Properties in Head and Neck Cancer Cells that are Effectively Counteracted by the Mithralog EC-8042
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description
onderzoeker
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հետազոտող
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R Rodríguez
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R Rodríguez
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R Rodríguez
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R Rodríguez
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R Rodríguez
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R Rodríguez
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R Rodríguez
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R Rodríguez
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R Rodriguez
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Rene Rodriguez-Gonzalez
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R Rodríguez
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R Rodríguez
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R Rodríguez
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R Rodríguez
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R Rodríguez
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rene-rodriguez8
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0000-0002-0768-7306