Chronic myeloid leukemia cells refractory/resistant to tyrosine kinase inhibitors are genetically unstable and may cause relapse and malignant progression to the terminal disease state.

Chronic myeloid leukemia cells refractory/resistant to tyrosine kinase inhibitors are genetically unstable and may cause relapse and malignant progression to the terminal disease state.

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http://www.wikidata.org/entity/Q37836926
BCR-ABL1 kinase inhibits uracil DNA glycosylase UNG2 to enhance oxidative DNA damage and stimulate genomic instability.Dosimetry for radiopharmaceutical therapyRadiopharmaceutical therapy in the era of precision medicine.The role of dasatinib in the management of chronic myeloid leukemiaBMI1 reprogrammes histone acetylation and enhances c-fos pathway via directly binding to Zmym3 in malignant myeloid progressionHuman induced pluripotent stem cells from basic research to potential clinical applications in cancerWhy imatinib remains an exception of cancer research.Cellular and Molecular Networks in Chronic Myeloid Leukemia: The Leukemic Stem, Progenitor and Stromal Cell Interplay.The bone marrow microenvironment as niche retreats for hematopoietic and leukemic stem cells.Chronic myeloid leukemia 2011: successes, challenges, and strategies--proceedings of the 5th annual BCR-ABL1 positive and BCR-ABL1 negative myeloproliferative neoplasms workshop.ETV6/RUNX1 induces reactive oxygen species and drives the accumulation of DNA damage in B cells.Genomic instability is a principle pathologic feature of FLT3 ITD kinase activity in acute myeloid leukemia leading to clonal evolution and disease progression.
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Chronic myeloid leukemia cells refractory/resistant to tyrosine kinase inhibitors are genetically unstable and may cause relapse and malignant progression to the terminal disease state.

Item
http://www.wikidata.org/entity/Q37836926
description
article científic
@ca
article scientifique
@fr
articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on February 2011
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
@cs
name
Chronic myeloid leukemia cells ...... to the terminal disease state.
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Chronic myeloid leukemia cells ...... to the terminal disease state.
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type
label
Chronic myeloid leukemia cells ...... to the terminal disease state.
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Chronic myeloid leukemia cells ...... to the terminal disease state.
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prefLabel
Chronic myeloid leukemia cells ...... to the terminal disease state.
@en
Chronic myeloid leukemia cells ...... to the terminal disease state.
@nl
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Chronic myeloid leukemia cells ...... to the terminal disease state.
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10.3109/10428194.2010.546912
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