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Ex vivo expanded human regulatory T cells delay islet allograft rejection via inhibiting islet-derived monocyte chemoattractant protein-1 production in CD34+ stem cells-reconstituted NOD-scid IL2rγnull miceInhibition of intravascular thrombosis in murine endotoxemia by targeted expression of hirudin and tissue factor pathway inhibitor analogs to activated endothelium.Coagulation dysregulation as a barrier to xenotransplantation in the primatePotential factors influencing the development of thrombocytopenia and consumptive coagulopathy after genetically modified pig liver xenotransplantation.The use of eculizumab in renal transplantation.Enhanced effect of inhibition of thrombin on endothelium in murine endotoxaemia: specific inhibition of thrombocytopenia.Plasmapheresis as rescue therapy for systemic lupus erthyematosus-associated diffuse alveolar haemorrhageAre anti-endothelial cell antibodies a pre-requisite for the acute vascular rejection of xenografts?Tolerance or accommodation: the lesson from leflunomide.Major histocompatibility complex class II-expressing endothelial cells induce allospecific nonresponsiveness in naive T cellsA new and clinically relevant murine model of solid-organ transplant aspergillosis.Alpha1,3-galactosyltransferase gene-knockout pigs for xenotransplantation: where do we go from here?Paclitaxel-coated balloon fistuloplasty versus plain balloon fistuloplasty only to preserve the patency of arteriovenous fistulae used for haemodialysis (PAVE): study protocol for a randomised controlled trial.Progenitor cells and vascular disease.Factor VII promotes hepatocellular carcinoma progression through ERK-TSC signalingCan a combined screening/treatment programme prevent premature failure of renal transplants due to chronic rejection in patients with HLA antibodies: study protocol for the multicentre randomised controlled OuTSMART trial.Graft dysfunction in chronic antibody-mediated rejection correlates with B-cell-dependent indirect antidonor alloresponses and autocrine regulation of interferon-γ production by Th1 cells.B cells in renal transplantation: pathological aspects and therapeutic interventions.The roles of thrombin and protease-activated receptors in inflammation.Transplant accommodation--are the lessons learned from xenotransplantation pertinent for clinical allotransplantation?Optimising long-term graft survival: establishing the benefit of targeting B lymphocytes.APT070 (mirococept), a membrane-localizing C3 convertase inhibitor, attenuates early human islet allograft damage in vitro and in vivo in a humanized mouse model.Post-listing survival for highly sensitised patients on the UK kidney transplant waiting list: a matched cohort analysis.Organ Pretreatment With Cytotopic Endothelial Localizing Peptides to Ameliorate Microvascular Thrombosis and Perfusion Deficits in Ex Vivo Renal Hemoreperfusion Models.Organ Pretreatment with Cytotopic Endothelial Localising Peptides To Ameliorate Microvascular Thrombosis & Perfusion Deficits In Ex-vivo Renal Haemo-reperfusion Models.Prospects for xenografting.Difference in outcomes after antibody-mediated rejection between abo-incompatible and positive cross-match transplantations.Immunosuppression of direct T-cell-mediated xenorecognition in vitro.HLA-G inhibits the transendothelial cell migration of human NK cells: a strategy for inhibiting xenograft rejection.In vitro accommodation of immortalized porcine endothelial cells: resistance to complement mediated lysis and down-regulation of VCAM expression induced by low concentrations of polyclonal human IgG antipig antibodies.Expression of human tissue factor pathway inhibitor on vascular smooth muscle cells inhibits secretion of macrophage migration inhibitory factor and attenuates atherosclerosis in ApoE-/- mice.Clinical xenotransplantation of solid organs.Incidence and Outcome of C4d Staining With Tubulointerstitial Inflammation in Blood Group-incompatible Kidney Transplantation.Protease-activated receptor 1 activation is necessary for monocyte chemoattractant protein 1-dependent leukocyte recruitment in vivo.Atorvastatin or transgenic expression of TFPI inhibits coagulation initiated by anti-nonGal IgG binding to porcine aortic endothelial cells.Recipient tissue factor expression is associated with consumptive coagulopathy in pig-to-primate kidney xenotransplantation.Kidney transplantation with minimized maintenance: alemtuzumab induction with tacrolimus monotherapy--an open label, randomized trial.Exogenous interferon-gamma immunotherapy for invasive fungal infections in kidney transplant patients.Expression of tissue factor and initiation of clotting by human platelets and monocytes after incubation with porcine endothelial cells."Accomodated" pig endothelial cells promote nitric oxide-dependent Th-2 cytokine responses from human T cells.
P50
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P50
description
hulumtues
@sq
onderzoeker
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researcher
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հետազոտող
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name
Anthony Dorling
@ast
Anthony Dorling
@en
Anthony Dorling
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Anthony Dorling
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Anthony Dorling
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type
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Anthony Dorling
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Anthony Dorling
@en
Anthony Dorling
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Anthony Dorling
@nl
Anthony Dorling
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prefLabel
Anthony Dorling
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Anthony Dorling
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Anthony Dorling
@es
Anthony Dorling
@nl
Anthony Dorling
@sl
P106
P1153
7003841124
P21
P31
P496
0000-0003-3102-2600