Small-molecule protein kinase inhibitors and their effects on the immune system: implications for cancer treatment.
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Signaling Circuits and Regulation of Immune Suppression by Ovarian Tumor-Associated MacrophagesDendritic cell vaccination, immune regulation, and clinical outcomes in ovarian cancermTOR and MEK1/2 inhibition differentially modulate tumor growth and the immune microenvironment in syngeneic models of oral cavity cancer.Overcoming barriers to effective immunotherapy: MDSCs, TAMs, and Tregs as mediators of the immunosuppressive microenvironment in head and neck cancer.Enhanced Tumor Control with Combination mTOR and PD-L1 Inhibition in Syngeneic Oral Cavity CancersIntrinsic modulation of lymphocyte function by stromal cell network: advance in therapeutic targeting of cancer.Immunity to TB and targets for immunotherapy.Immunological heterogeneity of the RCC microenvironment: do targeted therapies influence immune response?Canonical and new generation anticancer drugs also target energy metabolism.Cancer Vaccines: Enhanced Immunogenic Modulation through Therapeutic Combinations.Inhibition of Oncogenic Transcription Factor REL by the Natural Product Derivative Calafianin Monomer 101 Induces Proliferation Arrest and Apoptosis in Human B-Lymphoma Cell Lines.Oncogenic BRAF(V600E) promotes stromal cell-mediated immunosuppression via induction of interleukin-1 in melanoma.Genomic characterization of explant tumorgraft models derived from fresh patient tumor tissue.Analysis of PI3K pathway components in human cancers.MV140, a sublingual polyvalent bacterial preparation to treat recurrent urinary tract infections, licenses human dendritic cells for generating Th1, Th17, and IL-10 responses via Syk and MyD88.Agonist immunotherapy restores T cell function following MEK inhibition improving efficacy in breast cancer.Developing a novel dual PI3K-mTOR inhibitor from the prodrug of a metabolite.Modulation of cabozantinib efficacy by the prostate tumor microenvironment.Repurposing of Kinase Inhibitors as Broad-Spectrum Antiviral Drugs.Inhibitor of apoptosis protein (IAP) antagonists demonstrate divergent immunomodulatory properties in human immune subsets with implications for combination therapy.CAR-T cells and combination therapies: What's next in the immunotherapy revolution?Novel Protein Arginine Methyltransferase 8 Isoform Is Essential for Cell Proliferation.Breakthroughs in modern cancer therapy and elusive cardiotoxicity: Critical research-practice gaps, challenges, and insights.
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Small-molecule protein kinase inhibitors and their effects on the immune system: implications for cancer treatment.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on February 2011
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Small-molecule protein kinase ...... ications for cancer treatment.
@en
Small-molecule protein kinase ...... ications for cancer treatment.
@nl
type
label
Small-molecule protein kinase ...... ications for cancer treatment.
@en
Small-molecule protein kinase ...... ications for cancer treatment.
@nl
prefLabel
Small-molecule protein kinase ...... ications for cancer treatment.
@en
Small-molecule protein kinase ...... ications for cancer treatment.
@nl
P2860
P356
P1433
P1476
Small-molecule protein kinase ...... ications for cancer treatment.
@en
P2093
Patrick A Ott
P2860
P304
P356
10.2217/IMT.10.99
P50
P577
2011-02-01T00:00:00Z