From conventional to unusual enzyme inhibitor scaffolds: the quest for target specificity.
about
Structurally Sophisticated Octahedral Metal Complexes as Highly Selective Protein Kinase InhibitorsAn Organometallic Inhibitor for the Human Repair Enzyme 7,8-Dihydro-8-oxoguanosine TriphosphataseNon-ATP-Mimetic Organometallic Protein Kinase Inhibitorp21-Activated kinase inhibitors: a patent reviewOrganometallic Titanocene-Gold Compounds as Potential Chemotherapeutics in Renal Cancer. Study of their Protein Kinase Inhibitory Properties.Inhibition of Beta-Amyloid Fibrillation by Luminescent Iridium(III) Complex ProbesAxial ligand exchange of N-heterocyclic cobalt(III) Schiff base complexes: molecular structure and NMR solution dynamics.Heterometallic titanium-gold complexes inhibit renal cancer cells in vitro and in vivo.Targeted therapy vs. DNA-adduct formation-guided design: thoughts about the future of metal-based anticancer drugs.Photofunctional triplet excited states of cyclometalated Ir(III) complexes: beyond electroluminescence.Metal complex catalysis in living biological systems.Molecular imprinting science and technology: a survey of the literature for the years 2004-2011.Metal-based drugs that break the rules.Organometallic rhodium(III) and iridium(III) cyclopentadienyl complexes with curcumin and bisdemethoxycurcumin co-ligands.Effects of the ruthenium-based drug NAMI-A on the roles played by TGF-β1 in the metastatic process.RNA-seq analysis of the whole transcriptome of MDA-MB-231 mammary carcinoma cells exposed to the antimetastatic drug NAMI-A.Non-nitric oxide based metallovasodilators: synthesis, reactivity and biological studies.Synthesis and Structure of a Ternary Copper(II) Complex with Mixed Ligands of Diethylenetriamine and Picrate: DNA/Protein-Binding Property and In Vitro Anticancer Activity Studies.A metal-based tumour necrosis factor-alpha converting enzyme inhibitor.Precious metal carborane polymer nanoparticles: characterisation of micellar formulations and anticancer activity.Phenanthroline ligands are biologically more active than their corresponding ruthenium(II) arene complexes.Ruthenium-Arene-β-Carboline Complexes as Potent Inhibitors of Cyclin-Dependent Kinase 1: Synthesis, Characterization and Anticancer Mechanism Studies.A gold(III) porphyrin complex as an anti-cancer candidate to inhibit growth of cancer-stem cells.The [(Cp)M(CO)(3)] (M=Re, (99m)Tc) building block for imaging agents and bioinorganic probes: perspectives and limitations.Identification of 1,3-diiminoisoindoline carbohydrazides as potential antimalarial candidates.Programmable Downregulation of Enzyme Activity Using a Fever and NIR-Responsive Molecularly Imprinted Nanocomposite.Metal-conjugated affinity labels: a new concept to create enantioselective artificial metalloenzymes.Carborane-based design of a potent vitamin D receptor agonist.Prediction of kinase-inhibitor binding affinity using energetic parametersCopper-promoted reductive homocoupling of quasi-aromatic iron(II) clathrochelates: boosting the inhibitory activity in a transcription assay.A Blocking Group Scan Using a Spherical Organometallic Complex Identifies an Unprecedented Binding Mode with Potent Activity In Vitro and In Vivo for the Opioid Peptide Dermorphin.Potent and selective inhibition of SH3 domains with dirhodium metalloinhibitors.Lyotropic lamellar phase formed from monolayered θ-shaped carborane-cage amphiphiles.Stereodynamics of metal-ligand assembly: what lies beneath the "simple" spectral signatures of C2-symmetric chiral chelates.Anti-inflammatory activity of electron-deficient organometallics.A selective artificial enzyme inhibitor based on nanoparticle-enzyme interactions and molecular imprinting.Designing organometallic compounds for catalysis and therapy.Cyclometalated Gold(III) Complexes Containing N-Heterocyclic Carbene Ligands Engage Multiple Anti-Cancer Molecular Targets.Strain-promoted azide-alkyne cycloaddition with ruthenium(II)-azido complexes.Is IQG-607 a Potential Metallodrug or Metallopro-Drug With a Defined Molecular Target in Mycobacterium tuberculosis?
P2860
Q27667351-84D22965-167A-4F85-952A-93900E6D8793Q27680660-F1AAA8CE-C4C7-47C6-BB34-6A1769F4FC67Q27681838-AF5C7324-EB09-45D6-AD69-24E7EAF0420FQ28261519-BC5BE095-E136-4059-B19A-9B2F988F22F2Q34576153-08B289EB-08EC-460D-B3E4-C17AC9A7A1BDQ36106553-70B17996-F412-4A2D-A52F-6887B71E4300Q36560196-6FC232DA-D51F-4C7F-A7DF-ADE6E852CB6FQ36908264-B1FAC6F2-4E83-4674-967C-5477AA28E7CFQ38011996-55AFC63D-99BA-4772-A14F-A23EA6E9B676Q38026452-9B6F2846-93CB-4C5F-84EE-EE07A0B525B4Q38068312-546D93F7-0B08-4DEF-BFDD-0D4FDF11B09FQ38202089-A0EB420B-E1C5-47A6-9BC6-A434FF42239FQ38714812-C4537469-FFDE-4D85-96DE-6C5C73195986Q38821097-41E79097-2F64-4E5C-A73F-EEF7187C17C9Q38835381-BAE6C9CD-FA0D-40E2-A8AF-C06F6D4C5996Q38838114-BF2B78F3-FE59-4D8D-84A2-9B69ABBAEC3EQ38856565-E1F33F7C-8513-442B-9DDA-DF22014A721EQ38912850-B6E28283-C974-49C8-9F80-283C12C76FA4Q38917646-ABD9EBAE-F92C-4C9C-9913-A89BB4BA1494Q38951818-C486A80F-AE30-4B87-B9C2-B40F24912A5DQ39044622-D894BA58-E84D-4595-9115-A616DAD7CD6EQ39121561-B7C0F86E-A1DA-43C5-8B2F-2FFAC04928E8Q39230008-AE2F24E2-0FE9-4184-9123-BEEB2D1B980DQ39278930-8F42BA82-EB05-4527-98CE-398FCB39899AQ39440906-61A9513F-0EDD-4611-ABF2-BDAF679E2E89Q40134416-ECAFCFCD-DC99-418E-9352-4C9B57F50A06Q40469516-4BBCDA50-8798-49FA-9315-0B4049ED613AQ41150070-ECFDBCD3-5E2C-4ECC-A8CF-4B4088ECE79DQ41787133-0F990020-E086-4EF6-A008-40EA497CFF07Q42237766-714E89A8-C4CC-4A1A-8BB7-E5B3A5CE71D4Q44339606-A4A869F1-54D6-4E77-AE45-150B66A46689Q45073074-088A5838-2BB0-48E3-8645-0F67DAD119FAQ45176749-E966661D-8541-4F1D-A785-03732820FECFQ45373018-59EF8015-774F-4C48-976A-516292EE0743Q47142235-414AEA1B-45DC-478E-965B-373E76C9D518Q47752614-A8836514-54E2-48DD-96C2-6885EA4188F9Q48007506-72723DD0-E9D5-4F9F-9E03-D5960C9FA663Q51117652-8825AE6B-F662-46A3-B9F6-4570EC1EE6D2Q54671888-578C310E-D55D-468A-BBCA-09A1117A7CC7Q55333929-9C020BA2-1180-4642-9E9C-4638499F68BA
P2860
From conventional to unusual enzyme inhibitor scaffolds: the quest for target specificity.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 15 February 2011
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
From conventional to unusual e ...... quest for target specificity.
@en
From conventional to unusual e ...... quest for target specificity.
@nl
type
label
From conventional to unusual e ...... quest for target specificity.
@en
From conventional to unusual e ...... quest for target specificity.
@nl
prefLabel
From conventional to unusual e ...... quest for target specificity.
@en
From conventional to unusual e ...... quest for target specificity.
@nl
P2860
P356
P1476
From conventional to unusual e ...... quest for target specificity.
@en
P2860
P304
P356
10.1002/ANIE.201005673
P407
P50
P577
2011-02-15T00:00:00Z