Genotoxicity of retroviral hematopoietic stem cell gene therapy.
about
The therapeutic potential of genome editing for β-thalassemiaTowards in vivo amplification: Overcoming hurdles in the use of hematopoietic stem cells in transplantation and gene therapyRetroviral integrations in gene therapy trialsIdentifying Cancer Driver Genes Using Replication-Incompetent Retroviral VectorsNeonatal gene therapy with a gamma retroviral vector in mucopolysaccharidosis VI cats.Retroviral-vector-mediated gene therapy to mucopolysaccharidosis I mice improves sensorimotor impairments and other behavioral deficits.Autoimmune dysregulation and purine metabolism in adenosine deaminase deficiency.Molecular mechanisms of retroviral integration site selection.Thymidine kinase suicide gene-mediated ganciclovir ablation of autologous gene-modified rhesus hematopoiesis.Quantitative shearing linear amplification polymerase chain reaction: an improved method for quantifying lentiviral vector insertion sites in transplanted hematopoietic cell systemsVISA--Vector Integration Site Analysis server: a web-based server to rapidly identify retroviral integration sites from next-generation sequencing.Ub-ISAP: a streamlined UNIX pipeline for mining unique viral vector integration sites from next generation sequencing data.Stem cell gene therapy: the risks of insertional mutagenesis and approaches to minimize genotoxicity.Large animal models for foamy virus vector gene therapy.A novel gammaretroviral shuttle vector insertional mutagenesis screen identifies SHARPIN as a breast cancer metastasis gene and prognostic biomarker.High efficiency restriction enzyme-free linear amplification-mediated polymerase chain reaction approach for tracking lentiviral integration sites does not abrogate retrieval bias.Evaluating risks of insertional mutagenesis by DNA transposons in gene therapy.The clinical applications of genome editing in HIV.Retargeted Foamy Virus Vectors Integrate Less Frequently Near Proto-oncogenes.Identification of Hematopoietic Stem Cell Engraftment Genes in Gene Therapy Studies.Realizing the potential of gene-based molecular therapies in bone repair.Evidence for the in vivo safety of insulated foamy viral vectorsViral Vectors: The Road to Reducing Genotoxicity.Insulated Foamy Viral Vectors.A novel approach to identify driver genes involved in androgen-independent prostate cancer.Development of a novel adenovirus-alphavirus hybrid vector with RNA replicon features for malignant hematopoietic cell transduction.Engineering Next-Generation BET-Independent MLV Vectors for Safer Gene Therapy.High-Throughput Mapping and Clonal Quantification of Retroviral Integration Sites.Clinical Applications of Genome Editing to HIV Cure.
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Genotoxicity of retroviral hematopoietic stem cell gene therapy.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 07 March 2011
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Genotoxicity of retroviral hematopoietic stem cell gene therapy.
@en
Genotoxicity of retroviral hematopoietic stem cell gene therapy.
@nl
type
label
Genotoxicity of retroviral hematopoietic stem cell gene therapy.
@en
Genotoxicity of retroviral hematopoietic stem cell gene therapy.
@nl
prefLabel
Genotoxicity of retroviral hematopoietic stem cell gene therapy.
@en
Genotoxicity of retroviral hematopoietic stem cell gene therapy.
@nl
P2860
P1476
Genotoxicity of retroviral hematopoietic stem cell gene therapy.
@en
P2093
Grant D Trobridge
P2860
P304
P356
10.1517/14712598.2011.562496
P407
P577
2011-03-07T00:00:00Z