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The biology of cancer testis antigens: putative function, regulation and therapeutic potential

The biology of cancer testis antigens: putative function, regulation and therapeutic potential

http://www.wikidata.org/entity/Q37849976

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Does it make sense to target one tumor cell chemotactic factor or its receptor when several chemotactic axes are involved in metastasis of the same cancer?Regulation of Differentiation by Calcium-Sensing Receptor in Normal and Tumoral Developing Nervous System Targeting cancer testis antigens for biomarkers and immunotherapy in colorectal cancer: Current status and challenges Functions of Aurora kinase C in meiosis and cancer AKAP4 is a circulating biomarker for non-small cell lung cancer CRNDE: A Long Non-Coding RNA Involved in CanceR, Neurobiology, and DEvelopment A novel human-derived antibody against NY-ESO-1 improves the efficacy of chemotherapy Meta-analysis of clinical data using human meiotic genes identifies a novel cohort of highly restricted cancer-specific marker genes.CT45A1 acts as a new proto-oncogene to trigger tumorigenesis and cancer metastasis.Re-adapting T cells for cancer therapy: from mouse models to clinical trials.Three steps to the immortality of cancer cells: senescence, polyploidy and self-renewal.Serum immunoreactivity of cancer/testis antigen OY-TES-1 and its tissues expression in glioma.The clinical value, regulatory mechanisms, and gene network of the cancer-testis gene STK31 in pancreatic cancer Glycerol-3-phosphate acyltranferase-2 behaves as a cancer testis gene and promotes growth and tumorigenicity of the breast cancer MDA-MB-231 cell line.Characterization of intrinsically disordered prostate associated gene (PAGE5) at single residue resolution by NMR spectroscopy High resolution X chromosome-specific array-CGH detects new CNVs in infertile males Trial Watch: Peptide-based anticancer vaccines.Identification of a class of human cancer germline genes with transcriptional silencing refractory to the hypomethylating drug 5-aza-2'-deoxycytidine.A novel cohort of cancer-testis biomarker genes revealed through meta-analysis of clinical data sets.Epigenetic mechanisms underlying the dynamic expression of cancer-testis genes, PAGE2, -2B and SPANX-B, during mesenchymal-to-epithelial transition.A search for novel cancer/testis antigens in lung cancer identifies VCX/Y genes, expanding the repertoire of potential immunotherapeutic targets.Improving T-cell therapy for relapsed EBV-negative Hodgkin lymphoma by targeting upregulated MAGE-A4 Roles of the Y chromosome genes in human cancers.A Panel of Cancer Testis Antigens and Clinical Risk Factors to Predict Metastasis in Colorectal Cancer.Cancer/testis (CT) antigens, carcinogenesis and spermatogenesis.SGI-110: DNA Methyltransferase Inhibitor Oncolytic Identification of Novel HLA-A*24:02-Restricted Epitope Derived from a Homeobox Protein Expressed in Hematological Malignancies.Immunotherapy targets in pediatric cancer.Melanoma antigen-specific effector T cell cytokine secretion patterns in patients treated with ipilimumab Epigenetic remodelling of gene expression profiles of neoplastic and normal tissues: immunotherapeutic implications Effect of cancer/testis antigen NY-SAR-35 on the proliferation, migration and invasion of cancer cells Cancer/testis antigens and urological malignancies Systematic identification of genes with a cancer-testis expression pattern in 19 cancer types.Targeting the membrane-anchored serine protease testisin with a novel engineered anthrax toxin prodrug to kill tumor cells and reduce tumor burden.Proteomic profiling of triple-negative breast carcinomas in combination with a three-tier orthogonal technology approach identifies Mage-A4 as potential therapeutic target in estrogen receptor negative breast cancer.SPAG9 is involved in hepatocarcinoma cell migration and invasion via modulation of ELK1 expression.The novelty of human cancer/testis antigen encoding genes in evolution Linker histone variant H1T targets rDNA repeats.Potential role of meiosis proteins in melanoma chromosomal instability Expression of cancer/testis antigens is correlated with improved survival in glioblastoma.

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The biology of cancer testis antigens: putative function, regulation and therapeutic potential

http://www.wikidata.org/entity/Q37849976

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 18 February 2011

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

The biology of cancer testis a ...... tion and therapeutic potential

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The biology of cancer testis a ...... ion and therapeutic potential.

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type

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The biology of cancer testis a ...... tion and therapeutic potential

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The biology of cancer testis a ...... ion and therapeutic potential.

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prefLabel

The biology of cancer testis a ...... tion and therapeutic potential

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The biology of cancer testis a ...... ion and therapeutic potential.

@nl

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J.MOLONC.2011.02.001

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Molecular Oncology

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The biology of cancer testis a ...... tion and therapeutic potential

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Alessia Covre

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Elisabetta Fratta

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Francesca Colizzi

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Giulia Parisi

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Hugues Jean Marie Nicolay

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Luca Sigalotti

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Riccardo Danielli

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Sandra Coral

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Reduced stability of retinoblastoma protein by gankyrin, an oncogenic ankyrin-repeat protein overexpressed in hepatomas

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164-182

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10.1016/J.MOLONC.2011.02.001

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2

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5

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2011-02-18T00:00:00Z

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