Pathophysiological response to hypoxia - from the molecular mechanisms of malady to drug discovery: drug discovery for targeting the tumor microenvironment.

Pathophysiological response to hypoxia - from the molecular mechanisms of malady to drug discovery: drug discovery for targeting the tumor microenvironment.

Item
http://www.wikidata.org/entity/Q37855419
Mechanisms linking excess adiposity and carcinogenesis promotionObesity and cancer: the role of adipose tissue and adipo-cytokines-induced chronic inflammationADIPOQ rs266729 G/C gene polymorphism and plasmatic adipocytokines connect metabolic syndrome to colorectal cancerAntitumor effect of D-erythrose in an abdominal metastatic model of colon carcinoma.MiR-29a modulates the angiogenic properties of human endothelial cells.Transfection of hypoxia-inducible factor-1 decoy oligodeoxynucleotides suppresses expression of vascular endothelial growth factor in oral squamous cell carcinoma cells.Optimization of biguanide derivatives as selective antitumor agents blocking adaptive stress responses in the tumor microenvironment.Overexpression of CD147 in ovarian cancer is initiated by the hypoxic microenvironment.Melatonin reverses tunicamycin-induced endoplasmic reticulum stress in human hepatocellular carcinoma cells and improves cytotoxic response to doxorubicin by increasing CHOP and decreasing survivin.Oligomer procyanidins (F2) repress HIF-1α expression in human U87 glioma cells by inhibiting the EGFR/ AKT/mTOR and MAPK/ERK1/2 signaling pathways in vitro and in vivo.Solution-phase synthesis and biological evaluation of triostin A and its analogues.Development of a reduction-responsive amino acid that induces peptide bond cleavage in hypoxic cells.
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Pathophysiological response to hypoxia - from the molecular mechanisms of malady to drug discovery: drug discovery for targeting the tumor microenvironment.

Item
http://www.wikidata.org/entity/Q37855419
description
article científic
@ca
article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
@tr
scientific article published on 16 March 2011
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Pathophysiological response to ...... ng the tumor microenvironment.
@en
Pathophysiological response to ...... ng the tumor microenvironment.
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type
label
Pathophysiological response to ...... ng the tumor microenvironment.
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Pathophysiological response to ...... ng the tumor microenvironment.
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prefLabel
Pathophysiological response to ...... ng the tumor microenvironment.
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Pathophysiological response to ...... ng the tumor microenvironment.
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Pathophysiological response to ...... ng the tumor microenvironment.
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P2093
P304
P31
P356
P433
P478
P577
P698
P921