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Mini review on tricyclic compounds as an inhibitor of trypanothione reductaseAllopurinol Resistance in Leishmania infantum from Dogs with Disease RelapseCheminformatic models based on machine learning for pyruvate kinase inhibitors of Leishmania mexicana.Screening strategies to identify new chemical diversity for drug development to treat kinetoplastid infections.Drug search for leishmaniasis: a virtual screening approach by grid computing.In vivo/In vitro immune responses to L. major isolates from patients with no clinical response to Glucantime.Designing and Cloning Molecular Constructs to Knock Out N-Acetylglucosamine Phosphatidylinositol De-N-Acetylase (GPI12) Gene in Leishmania major (MRHO/IR/75/ER).Treatment Outcome of the Drug-resistant Zoonotic Cutaneous Leishmaniasis by GlucantimeExploring the Association of Surface Plasmon Resonance with Recombinant MHC:Ig Hybrid Protein as a Tool for Detecting T Lymphocytes in Mice Infected with Leishmania (Leishmania) amazonensis.Drug resistance in leishmaniasis: current drug-delivery systems and future perspectives.Efficacy of a Binuclear Cyclopalladated Compound Therapy for Cutaneous Leishmaniasis in the Murine Model of Infection with Leishmania amazonensis and Its Inhibitory Effect on Topoisomerase 1B.Arginase Inhibitors: A Rational Approach Over One Century.An 8-hydroxyquinoline-containing polymeric micelle system is effective for the treatment of murine tegumentary leishmaniasis.In-silico Leishmania target selectivity of antiparasitic terpenoids.In silico search of energy metabolism inhibitors for alternative leishmaniasis treatments.4-Acetoxydolastane diterpene from the Brazilian brown alga Canistrocarpus cervicornis as antileishmanial agent.Survey on efficacy of chloroformic extract of Artemisia annua against Giardia lamblia trophozoite and cyst in vitro.Ddi1-like protein from Leishmania major is an active aspartyl proteinase.Hypothesis: The potential application of doxorubicin against cutaneous leishmaniasis.Development, characterization, and in vitro biological performance of fluconazole-loaded microemulsions for the topical treatment of cutaneous leishmaniasisSynthesis and Comparison of In Vitro Leishmanicidal Activity of 5-(Nitroheteroaryl)-1,3,4-Thiadiazols Containing Cyclic Amine of Piperidin-4-ol at C-2 with Acyclic Amine Analogues against Iranian Strain of Leishmania major (MRHO/IR/75/ER).The effect of (-)-epigallocatechin 3-O--gallate in vitro and in vivo in Leishmania braziliensis: involvement of reactive oxygen species as a mechanism of action.Natural Sesquiterpene Lactones Induce Oxidative Stress in Leishmania mexicana.Target-Pathogen: a structural bioinformatic approach to prioritize drug targets in pathogens.Benzimidazole derivatives endowed with potent antileishmanial activity.In Vitro Evaluation of Antileishmanial Activity of Computationally Screened Compounds against Ascorbate Peroxidase To Combat Amphotericin B Drug Resistance.Leishmania infantum 5'-Methylthioadenosine Phosphorylase presents relevant structural divergence to constitute a potential drug target.Identification of novel leishmanicidal molecules by virtual and biochemical screenings targeting Leishmania eukaryotic translation initiation factor 4A.Mining of potential drug targets through the identification of essential and analogous enzymes in the genomes of pathogens of Glycine max, Zea mays and Solanum lycopersicum.Homology modelling, molecular docking, and molecular dynamics simulations reveal the inhibition of Leishmania donovani dihydrofolate reductase-thymidylate synthase enzyme by Withaferin-A.Predictive classification models and targets identification for betulin derivatives as Leishmania donovani inhibitors
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on April 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Drug targets in Leishmania.
@en
Drug targets in Leishmania.
@nl
type
label
Drug targets in Leishmania.
@en
Drug targets in Leishmania.
@nl
prefLabel
Drug targets in Leishmania.
@en
Drug targets in Leishmania.
@nl
P2860
P1476
Drug targets in Leishmania.
@en
P2093
Bhavna Chawla
P2860
P2888
P356
10.1007/S12639-010-0006-3
P577
2010-04-01T00:00:00Z