FANCP/SLX4: a Swiss army knife of DNA interstrand crosslink repair.
about
Human single-stranded DNA binding proteins are essential for maintaining genomic stabilityRegulation of Rev1 by the Fanconi anemia core complexFanconi anemia complementation group A (FANCA) protein has intrinsic affinity for nucleic acids with preference for single-stranded formsCooperativity of the SUMO and Ubiquitin Pathways in Genome StabilityExploiting the Fanconi Anemia Pathway for Targeted Anti-Cancer TherapyRegulation of FANCD2 and FANCI monoubiquitination by their interaction and by DNA.The genetic and biochemical basis of FANCD2 monoubiquitinationClinical evaluation of a multiple-gene sequencing panel for hereditary cancer risk assessmentRegulation of DNA cross-link repair by the Fanconi anemia/BRCA pathwayRAD51C--a new human cancer susceptibility gene for sporadic squamous cell carcinoma of the head and neck (HNSCC).Fanconi anemia group J helicase and MRE11 nuclease interact to facilitate the DNA damage response.Regulation of the Fanconi anemia pathway by a SUMO-like delivery networkFission yeast Pxd1 promotes proper DNA repair by activating Rad16XPF and inhibiting Dna2.Fanconi anemia and Bloom's syndrome crosstalk through FANCJ-BLM helicase interaction.Regulation of the Fanconi anemia pathway by a CUE ubiquitin-binding domain in the FANCD2 protein.Dimerization of SLX4 contributes to functioning of the SLX4-nuclease complex.The Simple Chordate Ciona intestinalis Has a Reduced Complement of Genes Associated with Fanconi Anemia.Activation of the DNA Damage Response Is a Conserved Function of HIV-1 and HIV-2 Vpr That Is Independent of SLX4 RecruitmentA distinct replication fork protection pathway connects Fanconi anemia tumor suppressors to RAD51-BRCA1/2.REV1 and DNA polymerase zeta in DNA interstrand crosslink repair.The roles of DNA polymerase ζ and the Y family DNA polymerases in promoting or preventing genome instability.Resolving branched DNA intermediates with structure-specific nucleases during replication in eukaryotes.The role of ubiquitin-binding domains in human pathophysiology.Stress and DNA repair biology of the Fanconi anemia pathwayFrom arrest to escape: HIV-1 Vpr cuts a deal.The Fanconi anemia ID2 complex: dueling saxes at the crossroads.Sensing of HIV-1 Infection in Tzm-bl Cells with Reconstituted Expression of STING.EGFR-activating mutations correlate with a Fanconi anemia-like cellular phenotype that includes PARP inhibitor sensitivity.Structural and Mechanistic Analysis of the Slx1-Slx4 EndonucleasePhysical interaction between SLX4 (FANCP) and XPF (FANCQ) proteins and biological consequences of interaction-defective missense mutations.A prototypical Fanconi anemia pathway in lower eukaryotes?Mutation analysis of the SLX4/FANCP gene in hereditary breast cancer.
P2860
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P2860
FANCP/SLX4: a Swiss army knife of DNA interstrand crosslink repair.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on June 2011
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
FANCP/SLX4: a Swiss army knife of DNA interstrand crosslink repair.
@en
FANCP/SLX4: a Swiss army knife of DNA interstrand crosslink repair.
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type
label
FANCP/SLX4: a Swiss army knife of DNA interstrand crosslink repair.
@en
FANCP/SLX4: a Swiss army knife of DNA interstrand crosslink repair.
@nl
prefLabel
FANCP/SLX4: a Swiss army knife of DNA interstrand crosslink repair.
@en
FANCP/SLX4: a Swiss army knife of DNA interstrand crosslink repair.
@nl
P2860
P356
P1433
P1476
FANCP/SLX4: a Swiss army knife of DNA interstrand crosslink repair.
@en
P2093
Kelly E Cybulski
Niall G Howlett
P2860
P304
P356
10.4161/CC.10.11.15818
P577
2011-06-01T00:00:00Z