Profound changes in drug metabolism enzymes and possible effects on drug therapy in neonates and children.
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Neonatal clinical pharmacologyEducational paper: do we need neonatal clinical pharmacologists?Changes in individual drug-independent system parameters during virtual paediatric pharmacokinetic trials: introducing time-varying physiology into a paediatric PBPK modelTemporal trends in antidepressant prescribing to children in UK primary care, 2000-2015.Ontogeny of human hepatic and intestinal transporter gene expression during childhood: age matters.CYP2C9 allelic variants and frequencies in a pediatric sickle cell disease cohort: implications for NSAIDs pharmacotherapy.Pharmacogenetic analysis of pediatric patients with acute lymphoblastic leukemia: a possible association between survival rate and ITPA polymorphismPaediatric pharmacokinetics: key considerations.The role of human carboxylesterases in drug metabolism: have we overlooked their importance?The impact of extracorporeal life support and hypothermia on drug disposition in critically ill infants and children.Clinical trials in neonates and children: Report of the pulmonary hypertension academic research consortium pediatric advisory committee.The pharmacokinetics of dexmedetomidine during long-term infusion in critically ill pediatric patients. A Bayesian approach with informative priors.Pediatric pharmacogenomics: a systematic assessment of ontogeny and genetic variation to guide the design of statin studies in children.Elimination kinetics of ethanol in a 5-week-old infant and a literature review of infant ethanol pharmacokineticsTailored tools to improve pharmacotherapy in infants.Drug metabolism for the paediatrician.Association Between Human Pain-Related Genotypes and Variability in Opioid Analgesia: An Updated Review.Ethics review of pediatric multi-center drug trials.Neonatal medicines research: challenges and opportunities.Pharmacometric Approaches to Personalize Use of Primarily Renally Eliminated Antibiotics in Preterm and Term Neonates.Quantitative clinical pharmacology practice for optimal use of antibiotics during the neonatal period.Population pharmacokinetics of intravenous clonidine for sedation during paediatric extracorporeal membrane oxygenation and continuous venovenous hemofiltration.Substantially increased sildenafil bioavailability after sublingual administration in children with congenital heart disease: two case reports.Guidance on the risk assessment of substances present in food intended for infants below 16 weeks of ageSemi-Mechanistic Model for Predicting the Dosing Rate in Children and Neonates for Drugs Mainly Eliminated by Cytochrome Metabolism.Proteomic Analysis of the Developmental Trajectory of Human Hepatic Membrane Transporter Proteins in the First Three Months of Life.Role of Farnesoid X Receptor in the Determination of Liver Transcriptome during Postnatal Maturation in Mice.First-Pass CYP3A-Mediated Metabolism of Midazolam in the Gut Wall and Liver in Preterm Neonates.Extrahepatic Drug-Metabolizing Enzymes and Their Significance
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P2860
Profound changes in drug metabolism enzymes and possible effects on drug therapy in neonates and children.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 08 May 2011
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Profound changes in drug metab ...... rapy in neonates and children.
@en
Profound changes in drug metab ...... rapy in neonates and children.
@nl
type
label
Profound changes in drug metab ...... rapy in neonates and children.
@en
Profound changes in drug metab ...... rapy in neonates and children.
@nl
prefLabel
Profound changes in drug metab ...... rapy in neonates and children.
@en
Profound changes in drug metab ...... rapy in neonates and children.
@nl
P2860
P1476
Profound changes in drug metab ...... rapy in neonates and children.
@en
P2860
P304
P356
10.1517/17425255.2011.577739
P407
P577
2011-05-08T00:00:00Z