The evolving world of protein-G-quadruplex recognition: a medicinal chemist's perspective.
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5'-UTR RNA G-quadruplexes: translation regulation and targetingRecA-Binding pilE G4 Sequence Essential for Pilin Antigenic Variation Forms Monomeric and 5′ End-Stacked Dimeric Parallel G-QuadruplexesStructure of Nucleophosmin DNA-binding Domain and Analysis of Its Complex with a G-quadruplex Sequence from the c-MYC PromoterStructure and possible function of a G-quadruplex in the long terminal repeat of the proviral HIV-1 genomeG-quadruplexes are specifically recognized and distinguished by selected designed ankyrin repeat proteinsThe cellular protein nucleolin preferentially binds long-looped G-quadruplex nucleic acids.Viral reverse transcriptases show selective high affinity binding to DNA-DNA primer-templates that resemble the polypurine tract.The intrinsically disordered amino-terminal region of human RecQL4: multiple DNA-binding domains confer annealing, strand exchange and G4 DNA binding.Detection of cyclic diguanylate G-octaplex assembly and interaction with proteinsEffect of G-quadruplex polymorphism on the recognition of telomeric DNA by a metal complex.Aptamer selection based on G4-forming promoter region.Structural and affinity analyses of g-quadruplex DNA aptamers for camptothecin derivativesIdentification and characterization of RNA guanine-quadruplex binding proteins.In vitro selection of DNA-based aptamers that exhibit RNA-like conformations using a chimeric oligonucleotide library that contains two different xeno-nucleic acids.Hit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement.Nucleolin stabilizes G-quadruplex structures folded by the LTR promoter and silences HIV-1 viral transcription.DNA aptamers to human immunodeficiency virus reverse transcriptase selected by a primer-free SELEX method: characterization and comparison with other aptamers.Synthesis, Binding and Antiviral Properties of Potent Core-Extended Naphthalene Diimides Targeting the HIV-1 Long Terminal Repeat Promoter G-QuadruplexesStrand invasion of DNA quadruplexes by PNA: comparison of homologous and complementary hybridization.Experimental approaches to identify cellular G-quadruplex structures and functions.Emerging trends in G-quadruplex biology--role in epigenetic and evolutionary events.Nucleophosmin mutations in acute myeloid leukemia: a tale of protein unfolding and mislocalization.G-quadruplex structures in the human genome as novel therapeutic targets.Coexistence of G-quadruplex and duplex domains within the secondary structure of 31-mer DNA thrombin-binding aptamer.The tale of RNA G-quadruplex.The Consequences of Overlapping G-Quadruplexes and i-Motifs in the Platelet-Derived Growth Factor Receptor β Core Promoter Nuclease Hypersensitive Element Can Explain the Unexpected Effects of Mutations and Provide Opportunities for Selective TargetThe cellular protein hnRNP A2/B1 enhances HIV-1 transcription by unfolding LTR promoter G-quadruplexes.RNA G-quadruplexes and their potential regulatory roles in translation.G4 motifs in human genes.Copper-Induced Topology Switching and Thrombin Inhibition with Telomeric DNA G-Quadruplexes.Effect of ATRX and G-Quadruplex Formation by the VNTR Sequence on α-Globin Gene Expression.Identification of novel interactors of human telomeric G-quadruplex DNAInterdependence of pyrene interactions and tetramolecular G4-DNA assembly
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The evolving world of protein-G-quadruplex recognition: a medicinal chemist's perspective.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 29 April 2011
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vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
The evolving world of protein- ...... dicinal chemist's perspective.
@en
The evolving world of protein- ...... dicinal chemist's perspective.
@nl
type
label
The evolving world of protein- ...... dicinal chemist's perspective.
@en
The evolving world of protein- ...... dicinal chemist's perspective.
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prefLabel
The evolving world of protein- ...... dicinal chemist's perspective.
@en
The evolving world of protein- ...... dicinal chemist's perspective.
@nl
P1433
P1476
The evolving world of protein-G-quadruplex recognition: a medicinal chemist's perspective
@en
P2093
Claudia Sissi
P304
P356
10.1016/J.BIOCHI.2011.04.018
P577
2011-04-29T00:00:00Z