Parthenolide, a sesquiterpene lactone, expresses multiple anti-cancer and anti-inflammatory activities.
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Salinomycin as a drug for targeting human cancer stem cellsRational Design of a Parthenolide-based Drug Regimen That Selectively Eradicates Acute Myelogenous Leukemia Stem CellsCooperative down-regulation of ribosomal protein L10 and NF-κB signaling pathway is responsible for the anti-proliferative effects by DMAPT in pancreatic cancer cellsInvolvement of Akt/NF-κB pathway in antitumor effects of parthenolide on glioblastoma cells in vitro and in vivo.Anti-inflammatory and antiosteoclastogenic activities of parthenolide on human periodontal ligament cells in vitro.Sesquiterpene lactones inhibit advanced oxidation protein product-induced MCP-1 expression in podocytes via an IKK/NF-κB-dependent mechanism.Distinct phenotypes of human prostate cancer cells associate with different adaptation to hypoxia and pro-inflammatory gene expression.Agents that inhibit bacterial biofilm formation.Activation of antioxidant response element in mouse primary cortical cultures with sesquiterpene lactones isolated from Tanacetum parthenium.Biofilm inhibitors that target amyloid proteins.The Nonartemisinin Sesquiterpene Lactones Parthenin and Parthenolide Block Plasmodium falciparum Sexual Stage Transmission.Dimers of Melampomagnolide B Exhibit Potent Anticancer Activity against Hematological and Solid Tumor CellsDevelopment of Anticancer Agents from Plant-Derived Sesquiterpene Lactones.Targeting aberrant glutathione metabolism to eradicate human acute myelogenous leukemia cells.Parthenolide generates reactive oxygen species and autophagy in MDA-MB231 cells. A soluble parthenolide analogue inhibits tumour growth and metastasis in a xenograft model of breast cancer.Sesquiterpene lactones: adverse health effects and toxicity mechanisms.Parthenolide could become a promising and stable drug with anti-inflammatory effects.The role of oxidative stress in anticancer activity of sesquiterpene lactones.Parthenolide attenuates 7,12-dimethylbenz[a]anthracene induced hamster buccal pouch carcinogenesis.Synthesis and antileukemic activities of C1-C10-modified parthenolide analogues.Parthenolide induces apoptosis by activating the mitochondrial and death receptor pathways and inhibits FAK-mediated cell invasion.Characterizing the "POAGome": A bioinformatics-driven approach to primary open-angle glaucoma.Antitumour effect of sesquiterpene (+)-chabranol on four human cancer cell lines by inducing apoptosis and autophagy.Cyclic AMP efflux inhibitors as potential therapeutic agents for leukemia.Emerging Importance of Phytochemicals in Regulation of Stem Cells Fate via Signaling Pathways.Natural Sesquiterpene Lactones Induce Oxidative Stress in Leishmania mexicana.Costunolide inhibits osteoclast differentiation by suppressing c-Fos transcriptional activity.Santamarine Inhibits NF-кB and STAT3 Activation and Induces Apoptosis in HepG2 Liver Cancer Cells via Oxidative Stress.Parthenolide induces apoptosis and autophagy through the suppression of PI3K/Akt signaling pathway in cervical cancer.Inhibition of AMPK/autophagy potentiates parthenolide-induced apoptosis in human breast cancer cells.Hepatoprotective effect of parthenolide in rat model of nonalcoholic fatty liver disease.Parthenolide inhibits pro-inflammatory cytokine production and exhibits protective effects on progression of collagen-induced arthritis in a rat model.Succinamide derivatives of melampomagnolide B and their anti-cancer activities.Synergistic anti-cancer effects of epigenetic drugs on medulloblastoma cells.Tanacetum polycephalum (L.) Schultz-Bip. induces mitochondrial-mediated apoptosis and inhibits migration and invasion in MCF7 cells.Effect of parthenolide on growth and apoptosis regulatory genes of human cancer cell lines.Budlein A, a Sesquiterpene Lactone From , Alleviates Pain and Inflammation in a Model of Acute Gout Arthritis in MiceParthenolide and DMAPT induce cell death in primitive CML cells through reactive oxygen speciesCrystal structure of 13-()-(2-amino-benzyl-idene)parthenolide
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Parthenolide, a sesquiterpene lactone, expresses multiple anti-cancer and anti-inflammatory activities.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on April 2012
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Parthenolide, a sesquiterpene ...... anti-inflammatory activities.
@en
Parthenolide, a sesquiterpene ...... anti-inflammatory activities.
@nl
type
label
Parthenolide, a sesquiterpene ...... anti-inflammatory activities.
@en
Parthenolide, a sesquiterpene ...... anti-inflammatory activities.
@nl
prefLabel
Parthenolide, a sesquiterpene ...... anti-inflammatory activities.
@en
Parthenolide, a sesquiterpene ...... anti-inflammatory activities.
@nl
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P1433
P1476
Parthenolide, a sesquiterpene ...... d anti-inflammatory activities
@en
P2093
Balkrishna Chand Thakuri
Young-Sang Koh
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P2888
P304
P356
10.1007/S10753-011-9346-0
P577
2012-04-01T00:00:00Z