G protein-coupled receptor kinases in normal and failing myocardium.
about
GRK2 in the heart: a GPCR kinase and beyondMechanisms of altered Ca²⁺ handling in heart failureG protein-coupled receptor kinase 2: a link between myocardial contractile function and cardiac metabolismAtomic Structure of GRK5 Reveals Distinct Structural Features Novel for G Protein-coupled Receptor KinasesThe expanding GRK interactome: Implications in cardiovascular disease and potential for therapeutic development.G protein-coupled Receptor Kinase 2 as a Therapeutic Target for Heart Failure.Overlapping and opposing functions of G protein-coupled receptor kinase 2 (GRK2) and GRK5 during heart development.Nuclear translocation of cardiac G protein-Coupled Receptor kinase 5 downstream of select Gq-activating hypertrophic ligands is a calmodulin-dependent process.Additional sex combs-like 2 is required for polycomb repressive complex 2 binding at select targetsDefective Resensitization in Human Airway Smooth Muscle Cells Evokes β-Adrenergic Receptor Dysfunction in Severe AsthmaInvolvement of nuclear factor κB (NF-κB) signaling pathway in regulation of cardiac G protein-coupled receptor kinase 5 (GRK5) expression.Structure-Based Design, Synthesis, and Biological Evaluation of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors.The evolving impact of g protein-coupled receptor kinases in cardiac health and diseaseG protein-coupled receptor kinase 5 phosphorylates nucleophosmin and regulates cell sensitivity to polo-like kinase 1 inhibition.Structure-Based Design of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors Based on Paroxetine.Gene targeting in ischemic heart disease and failure: translational and clinical studies."Canonical and non-canonical actions of GRK5 in the heart"Arginine vasopressin enhances cell survival via a G protein-coupled receptor kinase 2/β-arrestin1/extracellular-regulated kinase 1/2-dependent pathway in H9c2 cells.G protein-coupled receptor kinase 2 (GRK2) is localized to centrosomes and mediates epidermal growth factor-promoted centrosomal separation.GRK 2 level in peripheral blood lymphocytes of elderly patients with acute myocardial infarctionThe analysis of heterotaxy patients reveals new loss-of-function variants of GRK5Regulation of nuclear factor κB (NF-κB) in the nucleus of cardiomyocytes by G protein-coupled receptor kinase 5 (GRK5).Convergence of G protein-coupled receptor and S-nitrosylation signaling determines the outcome to cardiac ischemic injuryTargeting GRK2 by gene therapy for heart failure: benefits above β-blockade.Targeting cardiac β-adrenergic signaling via GRK2 inhibition for heart failure therapyDual role of GRK5 in cancer development and progression.β-adrenergic receptor-mediated cardiac contractility is inhibited via vasopressin type 1A-receptor-dependent signaling.Noncanonical Roles of G Protein-coupled Receptor Kinases in Cardiovascular Signaling.Obesity-induced cardiac lipid accumulation in adult mice is modulated by G protein-coupled receptor kinase 2 levels.Mdm2 regulates cardiac contractility by inhibiting GRK2-mediated desensitization of β-adrenergic receptor signaling.Prolonged AT1R activation induces CaV1.2 channel internalization in rat cardiomyocytes.Prodeath signaling of G protein-coupled receptor kinase 2 in cardiac myocytes after ischemic stress occurs via extracellular signal-regulated kinase-dependent heat shock protein 90-mediated mitochondrial targetingGrk5l controls heart development by limiting mTOR signaling during symmetry breaking.(-)-Epigallocatechin-3-gallate, the major green tea catechin, regulates the desensitization of β1 adrenoceptor via GRK2 in experimental heart failure.Utilizing a structure-based docking approach to develop potent G protein-coupled receptor kinase (GRK) 2 and 5 inhibitors.Alteration of β-Adrenoceptor Signaling in Left Ventricle of Acute Phase Takotsubo Syndrome: a Human Study
P2860
Q26851548-30EE14E3-6FD5-49AF-AB67-211ACD8B83DAQ27012758-20EE3DAC-AD5D-464B-A4E6-721F35ACEDCDQ27014769-6C6042D8-A27C-4817-9C64-BFF6B18F32D5Q28262711-00243773-2DA3-4FCD-AC70-57C4AC755601Q30250314-7642031A-F975-486A-AA03-A810DE7BC771Q33604042-2030D56D-C97B-4C7B-AE22-27E08120D3BFQ34249070-18DDA2CC-5DC6-41D0-A8E0-54A4451CDE4BQ34614326-1AE5D415-1356-4926-954E-3679F7455430Q34989584-1461C6C0-74CB-431A-96CB-650EB6AED4F7Q35645970-C5505232-7C27-4E71-95D3-7CCEDC7CBF05Q35921640-666B94D3-84E7-4607-9945-D927867F82B9Q35981205-977823AD-142D-47C4-B5F9-FBF341504474Q36000382-929661BF-8624-4075-A2E5-3B37134AFA1DQ36006990-5AACC93C-3B0A-41B2-B8B6-43A0592AACEDQ36316194-609DE8FB-39C4-42D8-8066-DA61798AED19Q36617570-ABA57B9C-B0B1-4847-A2B5-068CC989DDE4Q36679863-F7714DA8-C230-4DE0-B10B-CF10040CC5E5Q37027076-EEECFD3C-0182-4234-A0B8-668CB6970B27Q37167895-0C0654A3-6B7D-46BB-9C27-1C63986910C8Q37229933-1FA66897-C76E-433E-95BE-98D0963E1E3AQ37251124-BBD31978-1855-4897-8AC8-67B5064D9D90Q37388772-6D32951A-D433-43E7-B441-F7F39A0CAD5BQ37671204-3832055A-65FD-4AAF-AB09-2629916C11BCQ37984182-2E65E50F-B391-43DB-837B-C744BFE63CFCQ38153376-8C5DDDAD-E015-4D82-ADDA-CE9F7F461B29Q38871791-0FDFA638-8D07-4122-9D54-C1D129C5AFE1Q38957870-290C3B72-EF49-4495-AC11-0B8E76519F92Q39193250-AA1C5465-CE2C-4DFA-9CB9-AD1CD4548351Q39198039-22DEBC06-B9C6-4D8C-88E2-F17716C2DDC5Q40054908-9BF2FFF9-35D6-478C-BA60-071E3C3F858EQ41579873-40D7E961-63A8-4FAA-81C4-838880E5BD6CQ41903719-4E7DF12D-FB87-4C03-9D79-A9B8B6A2CBC5Q42651484-3938A731-2BC5-4117-A754-8F0D9492A7D6Q49788241-268BAC21-FA18-4679-9739-091772A0434DQ52601019-1852C3F4-B3B0-45E2-9690-A07253402CB2Q58708269-F557E459-D85B-421C-AABB-DA734617F6C9
P2860
G protein-coupled receptor kinases in normal and failing myocardium.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on June 2011
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
G protein-coupled receptor kinases in normal and failing myocardium.
@en
G protein-coupled receptor kinases in normal and failing myocardium.
@nl
type
label
G protein-coupled receptor kinases in normal and failing myocardium.
@en
G protein-coupled receptor kinases in normal and failing myocardium.
@nl
prefLabel
G protein-coupled receptor kinases in normal and failing myocardium.
@en
G protein-coupled receptor kinases in normal and failing myocardium.
@nl
P2093
P2860
P356
P1476
G protein-coupled receptor kinases in normal and failing myocardium.
@en
P2093
Jessica I Gold
Walter J Koch
Zheng Maggie Huang
P2860
P304
P356
10.2741/3898
P577
2011-06-01T00:00:00Z