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Osteopontin: a potentially important therapeutic target in cancer.

Osteopontin: a potentially important therapeutic target in cancer.

http://www.wikidata.org/entity/Q37896087

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Diagnostic value of osteopontin in ovarian cancer: a meta-analysis and systematic review The combination of serum insulin, osteopontin, and hepatocyte growth factor predicts time to castration-resistant progression in androgen dependent metastatic prostate cancer- an exploratory study Prognostic value of secreted phosphoprotein-1 in pleural effusion associated with non-small cell lung cancer Changes in the transcriptional profile in response to overexpression of the osteopontin-c splice isoform in ovarian (OvCar-3) and prostate (PC-3) cancer cell lines.Osteopontin upregulates the expression of glucose transporters in osteosarcoma cells.Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.Functional characterization of stromal osteopontin in melanoma progression and metastasis.Inhibitory effect of ethanol extract of Ocimum sanctum on osteopontin mediated metastasis of NCI-H460 non-small cell lung cancer cells.Osteopontin Potentiates Pulmonary Inflammation and Fibrosis by Modulating IL-17/IFN-γ-secreting T-cell Ratios in Bleomycin-treated Mice Osteopontin and thrombospondin-1 play opposite roles in promoting tumor aggressiveness of primary resected non-small cell lung cancer.Prognostic significance of osteopontin in patients with non-small cell lung cancer: results from a meta-analysis.Matricellular proteins in drug delivery: Therapeutic targets, active agents, and therapeutic localization Serum osteopontin and tissue inhibitor of metalloproteinase 1 as diagnostic and prognostic biomarkers for pancreatic adenocarcinoma Functional assessment of glioma pathogenesis by in vivo multi-parametric magnetic resonance imaging and in vitro analyses.Plasma osteopontin is a useful diagnostic biomarker for advanced non-small cell lung cancer.Association of osteopontin and cyclooxygenase-2 expression with breast cancer subtypes and their use as potential biomarkers Phosphoprotein secretome of tumor cells as a source of candidates for breast cancer biomarkers in plasma.Gene expression profiling in bladder cancer identifies potential therapeutic targets Osteopontin as a therapeutic target for cancer.Ablation of osteopontin suppresses N-methyl-N-nitrosourea and Helicobacter pylori-induced gastric cancer development in mice.Evaluation of copy number variation and gene expression in neurofibromatosis type-1-associated malignant peripheral nerve sheath tumours.Targeting osteopontin suppresses glioblastoma stem-like cell character and tumorigenicity in vivo.Hypoxia-driven osteopontin contributes to breast tumor growth through modulation of HIF1α-mediated VEGF-dependent angiogenesis.Osteopontin expressions correlate with WHO grades and predict recurrence in meningiomas.An Osteopontin/CD44 Axis in RhoGDI2-Mediated Metastasis Suppression Biological markers of prognosis, response to therapy and outcome in ovarian carcinoma.Tertiary structure prediction and identification of druggable pocket in the cancer biomarker - Osteopontin-c.Osteopontin is involved in TLR4 pathway contributing to ovarian cancer cell proliferation and metastasis.Epoxyazadiradione suppresses breast tumor growth through mitochondrial depolarization and caspase-dependent apoptosis by targeting PI3K/Akt pathway.The Rho GTPase signalling pathway in urothelial carcinoma.Deficient TSC1/TSC2-complex suppression of SOX9-osteopontin-AKT signalling cascade constrains tumour growth in tuberous sclerosis complex.Evaluation of osteopontin as a potential biomarker for central nervous system embryonal tumors.Osteopontin as a discriminating marker for pancreatic cancer and chronic pancreatitis.The Biology and Therapeutic Implications of Tumor Dormancy and Reactivation.SPP1 promotes ovarian cancer progression via Integrin β1/FAK/AKT signaling pathway.[SIBLING proteins: molecular tools for tumor progression and angiogenesis].Osteopontin promotes cancer cell drug resistance, invasion, and lactate production and is associated with poor outcome of patients with advanced non-small-cell lung cancer The Role of Mediators of Cell Invasiveness, Motility, and Migration in the Pathogenesis of Silent Corticotroph Adenomas

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Osteopontin: a potentially important therapeutic target in cancer.

http://www.wikidata.org/entity/Q37896087

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article científic

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article scientifique

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artigo científico

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bilimsel makale

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scientific article published on 25 July 2011

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vedecký článok

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vetenskaplig artikel

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vědecký článek

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name

Osteopontin: a potentially important therapeutic target in cancer.

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Osteopontin: a potentially important therapeutic target in cancer.

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Osteopontin: a potentially important therapeutic target in cancer.

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Osteopontin: a potentially important therapeutic target in cancer.

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Osteopontin: a potentially important therapeutic target in cancer.

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Osteopontin: a potentially important therapeutic target in cancer.

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14728222.2011.594438

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Expert Opinion on Therapeutic Targets

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Osteopontin: a potentially important therapeutic target in cancer.

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Anuja Ramdasi

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Anuradha Bulbule

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Dhanashri Thorat

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Goutam Chakraborty

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Gowrishankar Soundararajan

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Mansoor Ahmed

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Megha Sanyal

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Pompom Ghosh

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Priyanka Sharma

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Rajinder Kaur

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P2860

Osteopontin selectively regulates p70S6K/mTOR phosphorylation leading to NF-kappaB dependent AP-1-mediated ICAM-1 expression in breast cancer cells

The Hallmarks of Cancer

Hallmarks of Cancer: The Next Generation

Alternative translation of osteopontin generates intracellular and secreted isoforms that mediate distinct biological activities in dendritic cells

Osteopontin as a means to cope with environmental insults: regulation of inflammation, tissue remodeling, and cell survival

Exacerbated tissue destruction in DSS-induced acute colitis of OPN-null mice is associated with downregulation of TNF-alpha expression and non-programmed cell death

Osteopontin-c is a selective marker of breast cancer

cDNA cloning, mRNA distribution and heterogeneity, chromosomal location, and RFLP analysis of human osteopontin (OPN)

Osteopontin is produced by mast cells and affects IgE-mediated degranulation and migration of mast cells

An osteopontin splice variant induces anchorage independence in human breast cancer cells

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scholarly article

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10.1517/14728222.2011.594438

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9

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