about
A novel disrupter of telomere silencing 1-like (DOT1L) interaction is required for signal transducer and activator of transcription 1 (STAT1)-activated gene expressionEmbryonic stem cell and induced pluripotent stem cell: an epigenetic perspectiveTargeting histone methylation for cancer therapy: enzymes, inhibitors, biological activity and perspectivesThe many faces of histone H3K79 methylationTargeting histone methyltransferases and demethylases in clinical trials for cancer therapyEpigenetic Mechanisms in Developmental Alcohol-Induced Neurobehavioral DeficitsAn Overview of Chromatin-Regulating Proteins in CellsSynthesis of lysine methyltransferase inhibitorsImplication of posttranslational histone modifications in nucleotide excision repairChemical probes of histone lysine methyltransferasesEpigenetics of epithelial Na(+) channel-dependent sodium uptake and blood pressure regulationTargets, models and challenges in osteoarthritis researchThe functional diversity of protein lysine methylationRegulation of αENaC transcriptionEpigenetics and the control of the collecting duct epithelial sodium channelProtein methylation at the surface and buried deep: thinking outside the histone boxReprogramming of cell fate: epigenetic memory and the erasure of memories pastDot1-dependent histone H3K79 methylation promotes activation of the Mek1 meiotic checkpoint effector kinase by regulating the Hop1 adaptorPotent inhibition of DOT1L as treatment of MLL-fusion leukemiaEpigenetics in acute kidney injuryEpigenome-based personalized medicine in human cancerEpigenetic regulation of the intestinal epitheliumA chemical biology route to site-specific authentic protein modificationsDirect screening for chromatin status on DNA barcodes in yeast delineates the regulome of H3K79 methylation by Dot1Degree of recruitment of DOT1L to MLL-AF9 defines level of H3K79 Di- and tri-methylation on target genes and transformation potential.Discovery of Novel Dot1L Inhibitors through a Structure-Based Fragmentation ApproachHistone H2B monoubiquitination is a critical epigenetic switch for the regulation of autophagy.Role of the chromatin landscape and sequence in determining cell type-specific genomic glucocorticoid receptor binding and gene regulation.Effects of RNAi-mediated knockdown of histone methyltransferases on the sex-specific mRNA expression of Imp in the silkworm Bombyx mori.Drosophila melanogaster positive transcriptional elongation factors regulate metabolic and sex-biased expression in adults.DOT1L safeguards cartilage homeostasis and protects against osteoarthritis.A medicinal chemistry perspective for targeting histone H3 lysine-79 methyltransferase DOT1L.The use of small molecules in somatic-cell reprogramming.Conservation and divergence of the histone code in nucleomorphs.Quantitative proteomic discovery of dynamic epigenome changes that control human cytomegalovirus (HCMV) infectionHistone H3K79 methyltransferase Dot1L is directly activated by thyroid hormone receptor during Xenopus metamorphosis.GC skew at the 5' and 3' ends of human genes links R-loop formation to epigenetic regulation and transcription terminationO-GlcNAc signaling in cancer metabolism and epigeneticsIdentification of genetic suppressors of the Sin3A knockdown wing phenotypeIdentification of a DNA methylation signature to predict disease-free survival in locally advanced rectal cancer.
P2860
Q24293451-51B826DC-0542-4158-AA12-4DE810FE082FQ24633489-00E06E00-1529-4031-B00B-D405EA29D0CCQ26744441-CE578091-63C7-427F-B312-922A889BEF09Q26745514-2DAEFDC8-B3B3-452D-99D7-E006D2E370D8Q26746038-24EC62AC-EF0F-4DAD-8682-46937C7C36F4Q26748876-03FA0EEE-9607-422E-B189-76AC4232D04AQ26770154-DF738469-481F-4FD7-BA51-CEC6A6DB465FQ26799953-8485E0A9-09A2-4C81-AFAF-03458FD27578Q26823794-3664E1A8-63B5-49AB-A3F6-C37F70526AE6Q26829218-FEAAC9A8-F90A-4E18-ABDB-8F09686E7FA3Q26829745-B17DBEA7-C3B1-424A-B2F8-365DD1255A6BQ26850147-E65DD852-55C8-4AF2-A053-B83C86FD8A71Q26853164-3DD5A024-ACBE-4693-8587-CD730B19DF6BQ27007073-F45A7B83-FCC3-4E72-89D0-B7466416BF15Q27023846-803309A6-1B04-40DD-BC3E-15AF169A1DAEQ27025874-340507F5-3C9B-4FC3-A18C-F7BD46B22F4AQ27027748-41F367C9-10DD-485E-850F-19B7CA8619FEQ27324663-DE0E44AC-636D-4B4E-9D1A-B6E7DE7E4472Q27678800-A84F58E2-7C67-40BB-88B4-86120DC6B37CQ28080924-4BF452F3-0C5B-48E3-835D-DD7BC933D58EQ28083951-CC8759A0-27E6-4EE4-A0A3-1034617BCC47Q28084849-AA52082C-8950-4018-8BA9-6C5498B031FEQ28818016-CE31F335-0865-4A68-B1A4-1CADD81B6551Q28818751-7592FAE1-869E-4487-A536-77DD38592CF8Q30300029-FD6A6986-3485-47C0-8CD0-C64D8C22E087Q30392269-85DFA1CA-D93E-4586-9232-31FB43724787Q33554067-42637E80-86AF-4752-BF53-9540E3776869Q33557653-83BDF7E5-7794-40BA-AA4B-B89B72CABAEDQ33580782-01F2268B-DDBF-4257-8991-DD35F27784F2Q33702832-DAF79338-4E21-4CC3-AEEF-8E6EB5E2A1BAQ33827165-92A3A678-8182-4211-AB10-B6D4DBEEFEBCQ33943350-4B0779E6-D420-4ABB-9991-50ADE2AE2F69Q34038758-01AD2452-FAF3-40FA-A32A-66BF6A0F66E0Q34046593-658C2DE1-1732-48DA-9959-78FB3F46FDDAQ34157687-4EAFC7DF-E550-4DB9-A760-9536121BF292Q34338834-F0991720-A1CC-4D10-81C2-33E1F756E9FEQ34358463-13767AA9-D250-4B28-AD65-889E2062B34FQ34401725-F9567C07-982E-41C1-8C8C-48D6E518CE8FQ34482526-FE80B1FE-7DE4-4EC3-8BC1-4DF58FE838DBQ34483466-9708E4EC-8EA6-4470-81E3-56820E25071F
P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on July 2011
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
The diverse functions of Dot1 and H3K79 methylation.
@en
The diverse functions of Dot1 and H3K79 methylation.
@nl
type
label
The diverse functions of Dot1 and H3K79 methylation.
@en
The diverse functions of Dot1 and H3K79 methylation.
@nl
prefLabel
The diverse functions of Dot1 and H3K79 methylation.
@en
The diverse functions of Dot1 and H3K79 methylation.
@nl
P2860
P356
P1433
P1476
The diverse functions of Dot1 and H3K79 methylation
@en
P2093
Anh Tram Nguyen
P2860
P304
P356
10.1101/GAD.2057811
P50
P577
2011-07-01T00:00:00Z