Pharmacokinetic and pharmacogenetic predictive markers of irinotecan activity and toxicity.
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Evaluation of the effect of genetic variation on the relationship between statins, cardiovascular disease and cancerRetrospective study of irinotecan/cisplatin followed by etoposide/cisplatin or the reverse sequence in extensive-stage small cell lung cancer.The relationship between UGT1A1 gene polymorphism and irinotecan effect on extensive-stage small-cell lung cancer.Virtual Clinical Studies to Examine the Probability Distribution of the AUC at Target Tissues Using Physiologically-Based Pharmacokinetic Modeling: Application to Analyses of the Effect of Genetic Polymorphism of Enzymes and Transporters on IrinotecBioreactor technologies to support liver function in vitro.Clinical significance of UGT1A1 gene polymorphisms on irinotecan-based regimens as the treatment in metastatic colorectal cancerEfficacy and safety of pharmacotherapy in cancer-related psychiatric disorders across the trajectory of cancer care: a review.Quantification of irinotecan, SN38, and SN38G in human and porcine plasma by ultra high-performance liquid chromatography-tandem mass spectrometry and its application to hepatic chemoembolizationUGT1A1 predicts outcome in colorectal cancer treated with irinotecan and fluorouracil.Severe irinotecan-induced toxicity in a patient with UGT1A1 28 and UGT1A1 6 polymorphisms.A perspective on efflux transport proteins in the liverTumor-specific gene therapy for pancreatic cancer using human neural stem cells encoding carboxylesterase.Use of pharmacogenetics for predicting cancer prognosis and treatment exposure, response and toxicity.Methods: for studying pharmacogenetic profiles of combination chemotherapeutic drugs.Safety of palliative chemotherapy in advanced pancreatic cancer.Regulation of carboxylesterase-2 expression by p53 family proteins and enhanced anti-cancer activities among 5-fluorouracil, irinotecan and doxazolidine prodrug.Comparison of inhibition capability of scutellarein and scutellarin towards important liver UDP-glucuronosyltransferase (UGT) isoforms.Determination of irinotecan, SN-38 and SN-38 glucuronide using HPLC/MS/MS: Application in a clinical pharmacokinetic and personalized medicine in colorectal cancer patients.
P2860
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P2860
Pharmacokinetic and pharmacogenetic predictive markers of irinotecan activity and toxicity.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Pharmacokinetic and pharmacoge ...... notecan activity and toxicity.
@en
Pharmacokinetic and pharmacoge ...... notecan activity and toxicity.
@nl
type
label
Pharmacokinetic and pharmacoge ...... notecan activity and toxicity.
@en
Pharmacokinetic and pharmacoge ...... notecan activity and toxicity.
@nl
prefLabel
Pharmacokinetic and pharmacoge ...... notecan activity and toxicity.
@en
Pharmacokinetic and pharmacoge ...... notecan activity and toxicity.
@nl
P2093
P50
P1476
Pharmacokinetic and pharmacoge ...... inotecan activity and toxicity
@en
P2093
Guido Bocci
Marialuisa Polillo
Marianna Lastella
P304
P356
10.2174/138920011798062283
P407
P577
2011-12-01T00:00:00Z