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Structural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/CiMED12 mutations link intellectual disability syndromes with dysregulated GLI3-dependent Sonic Hedgehog signalingDeciphering the role of hedgehog signaling in pancreatic cancerHedgehog signaling: modulation of cancer properies and tumor mircroenvironmentTargeting the Sonic Hedgehog Signaling Pathway: Review of Smoothened and GLI InhibitorsAberrant GLI1 Activation in DNA Damage Response, Carcinogenesis and ChemoresistanceThe Impact of Hedgehog Signaling Pathway on DNA Repair Mechanisms in Human CancerRoles for Hedgehog signaling in adult organ homeostasis and repairAutophagy and regulation of cilia function and assemblyHedgehog signaling inhibitors as anti-cancer agents in osteosarcomaWrecked regulation of intrinsically disordered proteins in diseases: pathogenicity of deregulated regulatorsTargeted therapy for hepatocellular carcinoma: novel agents on the horizonCell cycle progression by the repression of primary cilia formation in proliferating cellsDecoding the phosphorylation code in Hedgehog signal transductionThe role of the cilium in normal and abnormal cell cycles: emphasis on renal cystic pathologiesContext-dependent signal integration by the GLI code: the oncogenic load, pathways, modifiers and implications for cancer therapySOX9 inhibits β-TrCP-mediated protein degradation to promote nuclear GLI1 expression and cancer stem cell properties.Sonidegib, a novel smoothened inhibitor for the treatment of advanced basal cell carcinomaMolecular pathways: novel approaches for improved therapeutic targeting of Hedgehog signaling in cancer stem cellsFOXC1 Activates Smoothened-Independent Hedgehog Signaling in Basal-like Breast CancerCyclopamine tartrate, an inhibitor of Hedgehog signaling, strongly interferes with mitochondrial function and suppresses aerobic respiration in lung cancer cellsActivation of the transcription factor GLI1 by WNT signaling underlies the role of SULFATASE 2 as a regulator of tissue regenerationThe intraflagellar transport protein IFT80 is required for cilia formation and osteogenesisGata6-Dependent GLI3 Repressor Function is Essential in Anterior Limb Progenitor Cells for Proper Limb DevelopmentAdult Gli2+/-;Gli3Δ699/+ Male and Female Mice Display a Spectrum of Genital MalformationIFT80 is essential for chondrocyte differentiation by regulating Hedgehog and Wnt signaling pathwaysA mutation in the mouse ttc26 gene leads to impaired hedgehog signalingDistinct populations within Isl1 lineages contribute to appendicular and facial skeletogenesis through the β-catenin pathwaySet7 mediated Gli3 methylation plays a positive role in the activation of Sonic Hedgehog pathway in mammalsDYRK1B as therapeutic target in Hedgehog/GLI-dependent cancer cells with Smoothened inhibitor resistanceMutations in the gene encoding IFT dynein complex component WDR34 cause Jeune asphyxiating thoracic dystrophySmoothened goes molecular: new pieces in the hedgehog signaling puzzleTargeting hedgehog signaling reduces self-renewal in embryonal rhabdomyosarcomaPituitary gland development and disease: from stem cell to hormone productionAdvanced treatment for basal cell carcinomas.Differential regulation of Gli proteins by Sufu in the lung affects PDGF signaling and myofibroblast development.The transcriptional activity of Gli1 is negatively regulated by AMPK through Hedgehog partial agonism in hepatocellular carcinoma.Arhgap36-dependent activation of Gli transcription factors.Deficits in human trisomy 21 iPSCs and neurons.The transcription factor GLI1 interacts with SMAD proteins to modulate transforming growth factor β-induced gene expression in a p300/CREB-binding protein-associated factor (PCAF)-dependent manner.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Gli proteins in development and disease.
@en
Gli proteins in development and disease.
@nl
type
label
Gli proteins in development and disease.
@en
Gli proteins in development and disease.
@nl
prefLabel
Gli proteins in development and disease.
@en
Gli proteins in development and disease.
@nl
P1476
Gli proteins in development and disease.
@en
P2093
Chi-Chung Hui
P304
P356
10.1146/ANNUREV-CELLBIO-092910-154048
P577
2011-07-21T00:00:00Z