about
2P2I HUNTER: a tool for filtering orthosteric protein-protein interaction modulators via a dedicated support vector machine.Focused chemical libraries--design and enrichment: an example of protein-protein interaction chemical space.Facile access to a heterocyclic, sp(3)-rich chemical scaffold via a tandem condensation/intramolecular nitrone-alkene [3+2] cycloaddition strategy.A metal-catalyzed enyne-cyclization step for the synthesis of bi- and tricyclic scaffolds amenable to molecular library production.Charting Biologically Relevant Spirocyclic Compound Space.Diastereo- and Enantioselective Iridium Catalyzed Carbonyl (α-Cyclopropyl)allylation via Transfer Hydrogenation.Development of an Intermittent-Flow Enantioselective Aza-Henry Reaction Using an Arylnitromethane and Homogeneous Brønsted Acid-Base Catalyst with Recycle.Cyclobutane and cyclobutene synthesis: catalytic enantioselective [2+2] cycloadditions.Enantioselective synthesis of new oxazolidinylthiazolidines as enzyme inhibitors.Nickel-Catalyzed Cross-Coupling of Vinyl Dioxanones to Form Enantiomerically Enriched Cyclopropanes.Square sugars: challenges and synthetic strategies.Dipyrazolo[1,5-a:4',3'-c]pyridines - a new heterocyclic system accessed via multicomponent reaction.Amino Azaxylylenes Photogenerated from o-Amido Imines: Photoassisted Access to Complex Spiro-Poly-Heterocycles.Hydrogen-bond landscapes, geometry and energetics of squaric acid and its mono- and dianions: a Cambridge Structural Database, IsoStar and computational study.Synthesis of oxaspirannic building blocks by regioselective nitroso-Diels-Alder reactions.Quinocidin, a Cytotoxic Antibiotic with an Unusual 3,4-Dihydroquinolizinium Ring and Michael Acceptor Reactivity toward Thiols.Nucleophilic Amination of Methoxy Arenes Promoted by a Sodium Hydride/Iodide Composite.A Stereoselective [3+1] Ring Expansion for the Synthesis of Highly Substituted Methylene Azetidines.Synthesis of Spirocyclic Pyrrolidines: Advanced Building Blocks for Drug Discovery.Exploration of a Au(i)-mediated three-component reaction for the synthesis of DNA-tagged highly substituted spiroheterocycles.Novel spirocyclic systems via multicomponent aza-Diels-Alder reaction.Synthesis of spiro[2.5]octa-4,7-dien-6-one with consecutive quaternary centers via 1,6-conjugate addition induced dearomatization of para-quinone methides.One-pot Sequential Reactions Featuring a Copper-catalyzed Amination Leading to Pyrido[2',1':2,3]imidazo[4,5-c]quinolines and Dihydropyrido[2',1':2,3]imidazo[4,5-c]quinolines.IMPPAT: A curated database of Indian Medicinal Plants, Phytochemistry And Therapeutics.Hydrogenation of nitroarenes using defined iron-phosphine catalysts.Benzofulvenes in Trienamine Catalysis: Stereoselective Spiroindene Synthesis.Synthesis and carbonic anhydrase inhibitory properties of new spiroindoline-substituted sulphonamide compounds.Cu-Catalyzed selective C3-formylation of imidazo[1,2-a]pyridine C-H bonds with DMSO using molecular oxygen.Microwave-Assisted Organocatalyzed Rearrangement of Propargyl Vinyl Ethers to Salicylaldehyde Derivatives: An Experimental and Theoretical Study.Trinuclear {Co(2+)-M(3+)-Co(2+)} complexes catalyze reduction of nitro compounds.Enantioselective reduction of sulfur-containing cyclic imines through biocatalysis.Discovery of new heterocycles with activity against human neutrophile elastase based on a boron promoted one-pot assembly reaction
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
New and unusual scaffolds in medicinal chemistry.
@en
New and unusual scaffolds in medicinal chemistry.
@nl
type
label
New and unusual scaffolds in medicinal chemistry.
@en
New and unusual scaffolds in medicinal chemistry.
@nl
prefLabel
New and unusual scaffolds in medicinal chemistry.
@en
New and unusual scaffolds in medicinal chemistry.
@nl
P356
P1476
New and unusual scaffolds in medicinal chemistry.
@en
P2093
Charles M Marson
P304
P356
10.1039/C1CS15119C
P577
2011-08-12T00:00:00Z