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Bioorthogonal cleavage and exchange of major histocompatibility complex ligands by employing azobenzene-containing peptidesNew Dioxaborolane Chemistry Enables [(18)F]-Positron-Emitting, Fluorescent [(18)F]-Multimodality Biomolecule Generation from the Solid PhaseEvaluation of ¹¹¹in-labelled exendin-4 derivatives containing different meprin β-specific cleavable linkersCovalent assembly of nanoparticles as a peptidase-degradable platform for molecular MRI.State-of-the-art in design rules for drug delivery platforms: lessons learned from FDA-approved nanomedicinesTarget identification of small molecules based on chemical biology approaches.Combinatorial screening for specific drug solubilizers with switchable release profiles.Cyclic acetals as cleavable linkers for affinity capture.Multiplex Azido-Group Isotopic Capture (MAGIC) Beads: Selective Analysis of Azido Compounds Using a Propargyl-based Cleavable Linker, a Proof of Concept.Increased brain uptake of targeted nanoparticles by adding an acid-cleavable linkage between transferrin and the nanoparticle core.A Simple and Efficient Synthesis of an Acid-labile Polyphosphoramidate by Organobase-catalyzed Ring-Opening Polymerization and Transformation to Polyphosphoester Ionomers by Acid TreatmentBioorthogonal approach to identify unsuspected drug targets in live cells.Activity-based probes for the study of proteases: recent advances and developments.Peptides and peptide conjugates: therapeutics on the upward path.Drug delivery and release systems for targeted tumor therapy.Developments and recent advancements in the field of endogenous amino acid selective bond forming reactions for bioconjugation.Smart linkers in polymer-drug conjugates for tumor-targeted delivery.Traceless Cleavage of Protein-Biotin Conjugates under Biologically Compatible Conditions.Controlling toxicity of Peptide-drug conjugates by different chemical linker structures.Target identification with quantitative activity based protein profiling (ABPP).A bombesin-shepherdin radioconjugate designed for combined extra- and intracellular targeting.A simple and effective cleavable linker for chemical proteomics applicationsDevelopment of a hypersensitive periodate-cleavable amino acid that is methionine- and disulfide-compatible and its application in MHC exchange reagents for T cell characterisation.Photoaffinity casting of a coumarin flag for rapid identification of ligand-binding sites within protein.An enzyme-responsive system programmed for the double release of bioactive molecules through an intracellular chemical amplification process.Cleavable trifunctional biotin reagents for protein labelling, capture and release.Enrichment of Specifically Labeled Proteins by an Immobilized Host Molecule.Target and identify: triazene linker helps identify azidation sites of labelled proteins via click and cleave strategy.Bioorthogonal Click and Release Reaction of Iminosydnones with Cycloalkynes.Deconstructing behavioral neuropharmacology with cellular specificity.Substituent Effects on the pH Sensitivity of Acetals and Ketals and Their Correlation with Encapsulation Stability in Polymeric Nanogels.Cleavable Linkers in Chemical Proteomics Applications.Palladium-Assisted Cleavage of Peptides and Proteins Containing a Backbone with Thiazolidine Linkage.A chemoselective cleavable fluorescence turn-ON linker for proteomic studies.Advances in micro- and nanotechnologies for the GLP-1-based therapy and imaging of pancreatic beta-cells.Advanced Activity-Based Protein Profiling Application Strategies for Drug Development.From solution to in-cell study of the chemical reactivity of acid sensitive functional groups: a rational approach towards improved cleavable linkers for biospecific endosomal release.An N-sulfanylethylanilide-based traceable linker for enrichment and selective labelling of target proteins.Genetic encoding of 2-aryl-5-carboxytetrazole-based protein photo-cross-linkers.Catch and release of concanavalin A by a mannose-immobilized photoaffinity PEGA resin coupled with a cleavable disulfide linker.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Cleavable linkers in chemical biology.
@en
Cleavable linkers in chemical biology.
@nl
type
label
Cleavable linkers in chemical biology.
@en
Cleavable linkers in chemical biology.
@nl
prefLabel
Cleavable linkers in chemical biology.
@en
Cleavable linkers in chemical biology.
@nl
P2093
P1476
Cleavable linkers in chemical biology.
@en
P2093
Alain Wagner
Geoffray Leriche
Louise Chisholm
P304
P356
10.1016/J.BMC.2011.07.048
P407
P577
2011-07-30T00:00:00Z