Enantioselective methodologies for the synthesis of spiro compounds.
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Therapeutic Potential of Spirooxindoles as Antiviral AgentsSkeletal diversification via heteroatom linkage control: preparation of bicyclic and spirocyclic scaffolds from N-substituted homopropargyl alcohols.Synthesis of a family of spirocyclic scaffolds: building blocks for the exploration of chemical spaceAdditive-assisted regioselective 1,3-dipolar cycloaddition of azomethine ylides with benzylideneacetoneN-Heterocyclic carbene-catalyzed oxidative [3 + 2] annulation of dioxindoles and enals: cross coupling of homoenolate and enolate.Total syntheses of natural products containing spirocarbocycles.ipso-Cyclization: an emerging tool for multifunctional spirocyclohexadienones.Streocontrolled construction of six vicinal stereogenic centers on spiropyrazolones via organocascade Michael/Michael/1,2-addition reactions.Highly Efficient Cascade Reaction for Selective Formation of Spirocyclobutenes from Dienallenes via Palladium-Catalyzed Oxidative Double Carbocyclization-Carbonylation-Alkynylation.Cross-trienamines in asymmetric organocatalysisEnantioselective cyclization of enamide-ynes and application to the synthesis of the kopsifoline coreCatalytic Enantioselective Synthesis of C1 - and C2 -Symmetric Spirobiindanones through Counterion-Directed Enolate C-Acylation.Highly efficient construction of bisspirooxindoles containing vicinal spirocenters through an organocatalytic modified Feist-Bénary reaction.Highly efficient enantioselective construction of bispirooxindoles containing three stereocenters through an organocatalytic cascade Michael-cyclization reaction.Diastereo- and enantioselective [3 + 3] cycloaddition of spirocyclopropyl oxindoles using both aldonitrones and ketonitrones.Asymmetric Synthesis of All-Carbon Quaternary Spirocycles via a Catalytic Enantioselective Allylic Alkylation Strategy.β2, 2 -Amino Acid N-Carboxyanhydrides Relying on Sequential Enantioselective C(4)-Functionalization of Pyrrolidin-2,3-diones and Regioselective Baeyer-Villiger Oxidation.One-pot asymmetric synthesis of a spiro[dihydrofurocoumarin/pyrazolone] scaffold by a Michael addition/I2-mediated cyclization sequence.Palladium-Catalyzed Oxidative Cascade Carbonylative Spirolactonization of Enallenols.Synergistic Catalysis: Enantioselective Ring Expansion of Vinyl Cyclopropanes Combining Four Catalytic Cycles for the Synthesis of Highly Substituted Spirocyclopentanes Bearing up to Four Stereocenters.Access to thiopyrano[2,3-b]indole via tertiary amine-catalyzed formal (3+3) annulations of β'-acetoxy allenoates with indoline-2-thiones.Catalytic enantioselective cascade Michael/cyclization reaction of 3-isothiocyanato oxindoles with exocyclic α,β-unsaturated ketones en route to 3,2'-pyrrolidinyl bispirooxindoles.Diastereoselective tandem oxidation/Michael/aldol reaction: unprecedented formation of dispirocyclopentanebisoxindoles and dispiro[acenaphthylene-1,1'-cyclopentane-3',1''-acenaphthylene]-2,2''diones.Enantioselective Synthesis of Chiral Oxime Ethers: Desymmetrization and Dynamic Kinetic Resolution of Substituted Cyclohexanones.Bifunctional Brønsted Base Catalyst Enables Regio-, Diastereo-, and Enantioselective Cα -Alkylation of β-Tetralones and Related Aromatic-Ring-Fused Cycloalkanones.A DBU-catalyzed Michael-Pinner-isomerization cascade reaction of 3-hydroxyoxindoles with isatylidene malononitriles: access to highly functionalized bispirooxindoles containing a fully substituted dihydrofuran motif.Enantio- and Diastereoselective Dehydrative "One-Step" Construction of Spirocarbocycles via a Ru/H+ -Catalyzed Tsuji-Trost Approach.An enantioselective synthesis of spiro-oxindole-based 3,4-dihydropyrroles via a Michael/cyclization cascade of 3-aminooxindoles with 2-enoylpyridines.Synergistic silver/scandium catalysis for divergent synthesis of skeletally diverse chromene derivatives.Highly diastereoselective synthesis of spiropyrazolones.Asymmetric triple relay catalysis: enantioselective synthesis of spirocyclic indolines through a one-pot process featuring an asymmetric 6π electrocyclization.Diastereo- and enantioselective construction of a bispirooxindole scaffold containing a tetrahydro-β-carboline moiety through an organocatalytic asymmetric cascade reaction.Gold/Brønsted acid relay catalysis for enantioselective construction of spirocyclic diketones.Mechanism and Selectivity of Ru(II) - and Rh(III) -Catalyzed Oxidative Spiroannulation of Naphthols and Phenols with Alkynes through a C-H Activation/Dearomatization Strategy.A tandem Prins spirocyclization for the stereoselective synthesis of tetrahydrospiro[chroman-2,4'-pyran] derivatives.The asymmetric synthesis of CF3-containing spiro[pyrrolidin-3,2'-oxindole] through the organocatalytic 1,3-dipolar cycloaddition reaction.Conjugate umpolung of β,β-disubstituted enals by dual catalysis with an N-heterocyclic carbene and a Brønsted acid: facile construction of contiguous quaternary stereocenters.The organocatalytic asymmetric Neber reaction for the enantioselective synthesis of spirooxindole 2H-azirines.Tin powder-promoted one-pot synthesis of 3-spiro-fused or 3,3'-disubstituted 2-oxindoles.Organocatalytic asymmetric [3+2] cycloaddition of N-2,2,2-trifluoroethylisatin ketimines with 3-alkenyl-5-arylfuran-2(3H)-ones.
P2860
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P2860
Enantioselective methodologies for the synthesis of spiro compounds.
description
article científic
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article scientifique
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articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
Enantioselective methodologies for the synthesis of spiro compounds.
@en
Enantioselective methodologies for the synthesis of spiro compounds.
@nl
type
label
Enantioselective methodologies for the synthesis of spiro compounds.
@en
Enantioselective methodologies for the synthesis of spiro compounds.
@nl
prefLabel
Enantioselective methodologies for the synthesis of spiro compounds.
@en
Enantioselective methodologies for the synthesis of spiro compounds.
@nl
P356
P1476
Enantioselective methodologies for the synthesis of spiro compounds.
@en
P304
P356
10.1039/C1CS15156H
P50
P577
2011-10-05T00:00:00Z