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SPOP promotes tumorigenesis by acting as a key regulatory hub in kidney cancerNovel activity of KRAB domain that functions to reinforce nuclear localization of KRAB-containing zinc finger proteins by interacting with KAP1Regulation of the Target of Rapamycin and Other Phosphatidylinositol 3-Kinase-Related Kinases by Membrane TargetingPhysiology and pathophysiology of the blood-brain barrier: P-glycoprotein and occludin trafficking as therapeutic targets to optimize central nervous system drug deliveryNeuropathy- and myopathy-associated mutations in human small heat shock proteins: Characteristics and evolutionary history of the mutation sitesQuantitative tracking of protein trafficking to the nucleus using cytosolic protein delivery by nanoparticle-stabilized nanocapsules.Automated quantification of the subcellular localization of multicompartment proteins via Q-SCAn.There Is No Simple Model of the Plasma Membrane OrganizationThe proinflammatory role of HECTD2 in innate immunity and experimental lung injuryDisrupting Dimerization Translocates Soluble Epoxide Hydrolase to PeroxisomesUnexpected gain of function for the scaffolding protein plectin due to mislocalization in pancreatic cancer.DNA polymerase β contains a functional nuclear localization signal at its N-terminus.Cancer-causing mutations in the tumor suppressor PALB2 reveal a novel cancer mechanism using a hidden nuclear export signal in the WD40 repeat motifPalmitoylated SCP1 is targeted to the plasma membrane and negatively regulates angiogenesis.Downregulation of the Repressor Element 1-Silencing Transcription Factor (REST) Is Associated with Akt-mTOR and Wnt-β-Catenin Signaling in Prion Diseases Models.Nuclear export of misfolded SOD1 mediated by a normally buried NES-like sequence reduces proteotoxicity in the nucleus.The molecular mechanism for nuclear transport and its application.Protein localization analysis of essential genes in prokaryotes.Targeting nucleocytoplasmic transport in cancer therapyActivation-induced cytidine deaminase alters the subcellular localization of Tet family proteins.Mutations in GANAB, Encoding the Glucosidase IIα Subunit, Cause Autosomal-Dominant Polycystic Kidney and Liver DiseaseMutation spectrum in human colorectal cancers and potential functional relevance.Phosphorylation and nuclear translocation of integrin β4 induced by a chemical small molecule contribute to apoptosis in vascular endothelial cells.Immediate translation of Formin DIAPH1 mRNA after its exiting the nucleus is required for its perinuclear localization in fibroblastsSubcellular localization-dependent changes in EGFP fluorescence lifetime measured by time-resolved flow cytometryThe Uve1 endonuclease is regulated by the white collar complex to protect cryptococcus neoformans from UV damage.HybridGO-Loc: mining hybrid features on gene ontology for predicting subcellular localization of multi-location proteinsDiscovery of 14-3-3 protein-protein interaction inhibitors that sensitize multidrug-resistant cancer cells to doxorubicin and the Akt inhibitor GSK690693.Bioimaging-based detection of mislocalized proteins in human cancers by semi-supervised learning.EPMA position paper in cancer: current overview and future perspectives.Targets of Wnt/ß-catenin transcription in penile carcinoma.A systematic analysis of human lipocalin family and its expression in esophageal carcinoma.The Sub-Cellular Localization of WRAP53 Has Prognostic Impact in Breast CancerLandscape of EGFR signaling network in human cancers: biology and therapeutic response in relation to receptor subcellular locationsSparse regressions for predicting and interpreting subcellular localization of multi-label proteinsSynthetic physical interactions map kinetochore regulators and regions sensitive to constitutive Cdc14 localization.Extent of pre-translational regulation for the control of nucleocytoplasmic protein localization.Understanding renal nuclear protein accumulation: an in vitro approach to explain an in vivo phenomenon.REST alleviates neurotoxic prion peptide-induced synaptic abnormalities, neurofibrillary degeneration and neuronal death partially via LRP6-mediated Wnt-β-catenin signaling.Mutations in the C-terminal region affect subcellular localization of crucian carp herpesvirus (CaHV) GPCR.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Protein localization in disease and therapy.
@en
Protein localization in disease and therapy.
@nl
type
label
Protein localization in disease and therapy.
@en
Protein localization in disease and therapy.
@nl
prefLabel
Protein localization in disease and therapy.
@en
Protein localization in disease and therapy.
@nl
P356
P1476
Protein localization in disease and therapy
@en
P2093
Mien-Chie Hung
P304
P356
10.1242/JCS.089110
P407
P577
2011-10-01T00:00:00Z