Hybrid-based multi-target ligands for the treatment of Alzheimer's disease.
about
Interaction of prion protein with acetylcholinesterase: potential pathobiological implications in prion diseases.Multitarget Strategy to Address Alzheimer's Disease: Design, Synthesis, Biological Evaluation, and Computational Studies of Coumarin-Based Derivatives.Multi-Target-Directed Ligands and other Therapeutic Strategies in the Search of a Real Solution for Alzheimer's Disease.Clinical utility of neuroprotective agents in neurodegenerative diseases: current status of drug development for Alzheimer's, Parkinson's and Huntington's diseases, and amyotrophic lateral sclerosis.The structural evolution of β-secretase inhibitors: a focus on the development of small-molecule inhibitors.The impact of crystallization conditions on structure-based drug design: A case study on the methylene blue/acetylcholinesterase complexLigand-based Modeling for the Prediction of Pharmacophore Features for Multi-targeted Inhibition of the Arachidonic Acid Cascade.Multiple Ligands Targeting Cholinesterases and β-Amyloid: Synthesis, Biological Evaluation of Heterodimeric Compounds with Benzylamine Pharmacophore.Pharmacophore-based design and discovery of (-)-meptazinol carbamates as dual modulators of cholinesterase and amyloidogenesis.Pharmacophore generation, atom-based 3D-QSAR, HQSAR and activity cliff analyses of benzothiazine and deazaxanthine derivatives as dual A2A antagonists/MAO‑B inhibitors.Design, Synthesis and Evaluation of Hesperetin Derivatives as Potential Multifunctional Anti-Alzheimer Agents.Synthesis and Biological Assessment of Racemic Benzochromenopyrimidinimines as Antioxidant, Cholinesterase, and Aβ1-42 Aggregation Inhibitors for Alzheimer's Disease Therapy.Cholinesterases in Biorecognition and Biosensors Construction: A ReviewBenzofuran-Chalcone Hybrids as Potential Multifunctional Agents against Alzheimer’s Disease: Synthesis and in vivo Studies with TransgenicCaenorhabditis elegans
P2860
Q35247531-18633773-0882-452D-995C-B4925EEB10BBQ35823536-1C467F77-50EB-42CA-9FCB-8675FD462819Q37559812-056AFD6F-E4E8-4F25-9742-D3CF12286113Q38022265-4AAF3860-7EFF-4362-92AA-0786656CC8DDQ38127826-3E4B7162-7268-4A7B-B997-4FD1131C2CAFQ39909419-32AB1ECD-045F-4AD1-8737-887400A6987CQ47678019-930AC8B8-28AB-40CC-A169-A28AA5AB7314Q48150230-7A4776B8-D58E-48AD-90CF-B8FB2EB59DCCQ50678690-2649B373-A383-4BD1-83F7-1767F41A982DQ50880865-10195B80-6EED-4E6B-94C4-B8F8F6C78D29Q53182177-504AA7FD-AF66-4644-ADD2-BCED089CD7A0Q53372587-08409DC0-486E-4802-88E0-9FB8E6F1A1FCQ58294482-CFD1BEA5-EF2F-425C-BFE5-8277083F1B43Q58930773-D5DC37DE-AC7F-4FC2-A77E-2FEF1F60822D
P2860
Hybrid-based multi-target ligands for the treatment of Alzheimer's disease.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh
2011年學術文章
@zh-hant
name
Hybrid-based multi-target ligands for the treatment of Alzheimer's disease.
@en
Hybrid-based multi-target ligands for the treatment of Alzheimer's disease.
@nl
type
label
Hybrid-based multi-target ligands for the treatment of Alzheimer's disease.
@en
Hybrid-based multi-target ligands for the treatment of Alzheimer's disease.
@nl
prefLabel
Hybrid-based multi-target ligands for the treatment of Alzheimer's disease.
@en
Hybrid-based multi-target ligands for the treatment of Alzheimer's disease.
@nl
P2093
P1476
Hybrid-based multi-target ligands for the treatment of Alzheimer's disease.
@en
P2093
Alessandra Bisi
Angela Rampa
Federica Belluti
Silvia Gobbi
P304
P356
10.2174/156802611798184409
P577
2011-11-01T00:00:00Z