Persistence: mechanisms for triggering and enhancing phenotypic variability.
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Toxin-Antitoxin Modules Are Pliable Switches Activated by Multiple Protease PathwaysPersisters-as elusive as everIndividuality, phenotypic differentiation, dormancy and 'persistence' in culturable bacterial systems: commonalities shared by environmental, laboratory, and clinical microbiologyInterplay between gene expression noise and regulatory network architectureImproved statistical analysis of low abundance phenomena in bimodal bacterial populationsHipBA-promoter structures reveal the basis of heritable multidrug toleranceA novel single-cell screening platform reveals proteome plasticity during yeast stress responsesMicrowell devices with finger-like channels for long-term imaging of HIV-1 expression kinetics in primary human lymphocytesPersistence to anti-cancer treatments in the stationary to proliferating transition.Selective target inactivation rather than global metabolic dormancy causes antibiotic tolerance in uropathogens.Survival of Vibrio cholerae in nutrient-poor environments is associated with a novel "persister" phenotype.Pharmacodynamics, population dynamics, and the evolution of persistence in Staphylococcus aureusHipA-mediated antibiotic persistence via phosphorylation of the glutamyl-tRNA-synthetase.Limits to compensatory adaptation and the persistence of antibiotic resistance in pathogenic bacteria.Vibrio cholerae persisted in microcosm for 700 days inhibits motility but promotes biofilm formation in nutrient-poor lake water microcosms.Stochastic developmental variation, an epigenetic source of phenotypic diversity with far-reaching biological consequences.On the translocation of bacteria and their lipopolysaccharides between blood and peripheral locations in chronic, inflammatory diseases: the central roles of LPS and LPS-induced cell death.An evolutionary role for HIV latency in enhancing viral transmission.Physiologic Stresses Reveal a Salmonella Persister State and TA Family Toxins Modulate Tolerance to These Stresses.Inhibition of stationary phase respiration impairs persister formation in E. coli.The Global Transcription Factor Lrp Controls Virulence Modulation in Xenorhabdus nematophilaTranscriptional Adaptation of Drug-tolerant Mycobacterium tuberculosis During Treatment of Human TuberculosisDevelopment of Persister-FACSeq: a method to massively parallelize quantification of persister physiology and its heterogeneity.Stationary-Phase Persisters to Ofloxacin Sustain DNA Damage and Require Repair Systems Only during Recovery.The heterogeneous evolution of multidrug-resistant Mycobacterium tuberculosis.Interpreting phenotypic antibiotic tolerance and persister cells as evolution via epigenetic inheritanceDisruption of Membrane by Colistin Kills Uropathogenic Escherichia coli Persisters and Enhances Killing of Other AntibioticsDendrimers--revolutionary drugs for infectious diseases.The role of metabolism in bacterial persistenceStress-induced remodeling of the bacterial proteome.Staphylococcus aureus adapts to oxidative stress by producing H2O2-resistant small-colony variants via the SOS response.Toxin-antitoxin systems in bacterial growth arrest and persistence.Phenotypic Resistance to Antibiotics.Phosphorylation-induced conformational dynamics in an intrinsically disordered protein and potential role in phenotypic heterogeneity.Fate-Regulating Circuits in Viruses: From Discovery to New Therapy Targets.Persistence and resistance as complementary bacterial adaptations to antibiotics.Phenotype switching is a natural consequence of Staphylococcus aureus replication.Design of a large-scale femtoliter droplet array for single-cell analysis of drug-tolerant and drug-resistant bacteriaScanLag: high-throughput quantification of colony growth and lag time.Relating switching rates between normal and persister cells to substrate and antibiotic concentrations: a mathematical modelling approach supported by experiments.
P2860
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P2860
Persistence: mechanisms for triggering and enhancing phenotypic variability.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh
2011年學術文章
@zh-hant
name
Persistence: mechanisms for triggering and enhancing phenotypic variability.
@en
Persistence: mechanisms for triggering and enhancing phenotypic variability.
@nl
type
label
Persistence: mechanisms for triggering and enhancing phenotypic variability.
@en
Persistence: mechanisms for triggering and enhancing phenotypic variability.
@nl
prefLabel
Persistence: mechanisms for triggering and enhancing phenotypic variability.
@en
Persistence: mechanisms for triggering and enhancing phenotypic variability.
@nl
P1476
Persistence: mechanisms for triggering and enhancing phenotypic variability.
@en
P304
P356
10.1016/J.GDE.2011.10.001
P577
2011-11-01T00:00:00Z