ROCKing Regeneration: Rho Kinase Inhibition as Molecular Target for Neurorestoration.
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Inhibition of rho kinase enhances survival of dopaminergic neurons and attenuates axonal loss in a mouse model of Parkinson's diseaseThe cytoskeletal arrangements necessary to neurogenesisEnhanced neurite outgrowth of human model (NT2) neurons by small-molecule inhibitors of Rho/ROCK signalingCoupling between apical tension and basal adhesion allow epithelia to collectively sense and respond to substrate topography over long distances.ROCK2 is a major regulator of axonal degeneration, neuronal death and axonal regeneration in the CNS.Viral vector-mediated downregulation of RhoA increases survival and axonal regeneration of retinal ganglion cells.Alpha-synuclein mutations impair axonal regeneration in models of Parkinson's disease.The rho kinase inhibitor Y-27632 improves motor performance in male SOD1(G93A) mice.Axon growth inhibition by RhoA/ROCK in the central nervous system.Targeted inhibition of the Shroom3-Rho kinase protein-protein interaction circumvents Nogo66 to promote axon outgrowth.Growth cone travel in space and time: the cellular ensemble of cytoskeleton, adhesion, and membrane.Therapy development for spinal muscular atrophy in SMN independent targets.Fasudil attenuates aggregation of α-synuclein in models of Parkinson's diseaseCornel Iridoid Glycoside Improves Locomotor Impairment and Decreases Spinal Cord Damage in Rats.Rho Kinase Inhibition with Fasudil in the SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis-Symptomatic Treatment Potential after Disease Onset.Axonal degeneration as a therapeutic target in the CNS.Rho-kinase: regulation, (dys)function, and inhibition.Chatting with the neighbors: crosstalk between Rho-kinase (ROCK) and other signaling pathways for treatment of neurological disorders.Regulation of Microglial Phagocytosis by RhoA/ROCK-Inhibiting Drugs.Acetyl-L-Carnitine Prevents Methamphetamine-Induced Structural Damage on Endothelial Cells via ILK-Related MMP-9 Activity.Topical administration of a Rock/Net inhibitor promotes retinal ganglion cell survival and axon regeneration after optic nerve injury.Frontiers in molecular neuroscience - résumé and perspective.Altered Expression of Growth Associated Protein-43 and Rho Kinase in Human Patients with Parkinson's Disease.AAV-mediated expression of BAG1 and ROCK2-shRNA promote neuronal survival and axonal sprouting in a rat model of rubrospinal tract injury.Directional migration of mesenchymal stem cells under an SDF-1α gradient on a microfluidic device.Neuroprotection by sildenafil: neuronal networks potentiation in acute experimental stroke.Rho kinase inhibition modulates microglia activation and improves survival in a model of amyotrophic lateral sclerosis.Varicose and cheerio collaborate with pebble to mediate semaphorin-1a reverse signaling in Drosophila.Rho kinase inhibition by fasudil in the striatal 6-hydroxydopamine lesion mouse model of Parkinson disease.ROCK as a therapeutic target for ischemic stroke.DGC-specific RHOA mutations maintained cancer cell survival and promoted cell migration via ROCK inactivation.
P2860
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P2860
ROCKing Regeneration: Rho Kinase Inhibition as Molecular Target for Neurorestoration.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
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2011年學術文章
@zh-hant
name
ROCKing Regeneration: Rho Kinase Inhibition as Molecular Target for Neurorestoration.
@en
ROCKing Regeneration: Rho Kinase Inhibition as Molecular Target for Neurorestoration.
@nl
type
label
ROCKing Regeneration: Rho Kinase Inhibition as Molecular Target for Neurorestoration.
@en
ROCKing Regeneration: Rho Kinase Inhibition as Molecular Target for Neurorestoration.
@nl
prefLabel
ROCKing Regeneration: Rho Kinase Inhibition as Molecular Target for Neurorestoration.
@en
ROCKing Regeneration: Rho Kinase Inhibition as Molecular Target for Neurorestoration.
@nl
P2860
P50
P356
P1476
ROCKing Regeneration: Rho Kinase Inhibition as Molecular Target for Neurorestoration
@en
P2093
Mathias Bähr
P2860
P356
10.3389/FNMOL.2011.00039
P577
2011-11-03T00:00:00Z