Lysosomal function and dysfunction: mechanism and disease.
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The crucial impact of lysosomes in aging and longevityIs the bovine lysosomal phospholipase B-like protein an amidase?Transmembrane 6 superfamily 1 (Tm6sf1) is a novel lysosomal transmembrane proteinHigh sphingomyelin levels induce lysosomal damage and autophagy dysfunction in Niemann Pick disease type A.Lysosomal-mediated waste clearance in retinal pigment epithelial cells is regulated by CRYBA1/βA3/A1-crystallin via V-ATPase-MTORC1 signaling.Instant membrane resealing in nlrp3 inflammmasome activation of endothelial cells.Inflammation and vitamin D: the infection connection(-)-Epigallocatechin-3-gallate induces non-apoptotic cell death in human cancer cells via ROS-mediated lysosomal membrane permeabilization.Cell death induced by ozone and various non-thermal plasmas: therapeutic perspectives and limitations.The contribution of lysosomotropism to autophagy perturbation.Lysosomal membrane permeabilization and autophagy blockade contribute to photoreceptor cell death in a mouse model of retinitis pigmentosa.Lipid-induced NOX2 activation inhibits autophagic flux by impairing lysosomal enzyme activityMegalin/Cubulin-Lysosome-mediated Albumin Reabsorption Is Involved in the Tubular Cell Activation of NLRP3 Inflammasome and Tubulointerstitial Inflammation.Nanoparticles restore lysosomal acidification defects: Implications for Parkinson and other lysosomal-related diseases.Altered lysosomal positioning affects lysosomal functions in a cellular model of Huntington's diseaseAutophagy flux in CA1 neurons of Alzheimer hippocampus: Increased induction overburdens failing lysosomes to propel neuritic dystrophy.The transcriptional landscape of age in human peripheral blood.Autophagy and neuronal cell death in neurological disordersThe autophagic lysosomal system in outflow pathway physiology and pathophysiology.Intracellular endothelin type B receptor-driven Ca2+ signal elicits nitric oxide production in endothelial cells.PPARα in lysosomal biogenesis: A perspective.β-glucuronidase mRNA levels are correlated with gait and working memory in premutation females: understanding the role of FMR1 premutation alleles.Suppression of lysosome function induces autophagy via a feedback down-regulation of MTOR complex 1 (MTORC1) activity.Comprehensive proteome analysis of lysosomes reveals the diverse function of macrophages in immune responses.Lysosomal targeting strategies for design and delivery of bioactive for therapeutic interventions.Lysosomal membrane permeabilization in cell death: new evidence and implications for health and disease.Proteinuria causes dysfunctional autophagy in the proximal tubule.Lysosomal and vacuolar sorting: not so different after all!Lipids, lysosomes, and autophagy.Urinary proteins induce lysosomal membrane permeabilization and lysosomal dysfunction in renal tubular epithelial cells.Exacerbating and reversing lysosomal storage diseases: from yeast to humans.Parkinsonian toxin-induced oxidative stress inhibits basal autophagy in astrocytes via NQO2/quinone oxidoreductase 2: Implications for neuroprotection.Mitochondrial Dysfunction in Lysosomal Storage Disorders.BAX channel activity mediates lysosomal disruption linked to Parkinson disease.GSK-3 and lysosomes meet in Alzheimer's disease.Lysosomal chymotrypsin induces mitochondrial fission in apoptotic cells by proteolytic activation of calcineurin.Ginkgetin induces autophagic cell death through p62/SQSTM1-mediated autolysosome formation and redox setting in non-small cell lung cancer.Surface air plasma-induced cell death and cytokine release of human keratinocytes in the context of psoriasis.In Search of a Converging Cellular Mechanism in Nanotoxicology and Nanomedicine in the Treatment of Cancer.Assembly of BODIPY-carbazole dyes with liposomes to fabricate fluorescent nanoparticles for lysosomal bioimaging in living cells.
P2860
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P2860
Lysosomal function and dysfunction: mechanism and disease.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Lysosomal function and dysfunction: mechanism and disease.
@en
Lysosomal function and dysfunction: mechanism and disease.
@nl
type
label
Lysosomal function and dysfunction: mechanism and disease.
@en
Lysosomal function and dysfunction: mechanism and disease.
@nl
prefLabel
Lysosomal function and dysfunction: mechanism and disease.
@en
Lysosomal function and dysfunction: mechanism and disease.
@nl
P356
P1476
Lysosomal function and dysfunction: mechanism and disease.
@en
P304
P356
10.1089/ARS.2011.4405
P577
2012-01-16T00:00:00Z