Providing β-lactams a helping hand: targeting the AmpC β-lactamase induction pathway.
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Catalytic spectrum of the penicillin-binding protein 4 of Pseudomonas aeruginosa, a nexus for the induction of β-lactam antibiotic resistanceIn vivo functional and molecular characterization of the Penicillin-Binding Protein 4 (DacB) of Pseudomonas aeruginosa.The sentinel role of peptidoglycan recycling in the β-lactam resistance of the Gram-negative Enterobacteriaceae and Pseudomonas aeruginosa.Overcoming drug resistance with alginate oligosaccharides able to potentiate the action of selected antibiotics.Distinct roles of major peptidoglycan recycling enzymes in β-Lactamase production in Shewanella oneidensisThe β-lactamase gene regulator AmpR is a tetramer that recognizes and binds the D-Ala-D-Ala motif of its repressor UDP-N-acetylmuramic acid (MurNAc)-pentapeptideMessenger functions of the bacterial cell wall-derived muropeptides.Bacterial cell-wall recycling.Phage therapy: eco-physiological pharmacology.Impact of AmpC Derepression on Fitness and Virulence: the Mechanism or the Pathway?Pseudomonas aeruginosa: targeting cell-wall metabolism for new antibacterial discovery and development.Loss of membrane-bound lytic transglycosylases increases outer membrane permeability and β-lactam sensitivity in Pseudomonas aeruginosa.The efflux inhibitor phenylalanine-arginine beta-naphthylamide (PAβN) permeabilizes the outer membrane of gram-negative bacteria.N152G, -S, and -T substitutions in CMY-2 β-lactamase increase catalytic efficiency for cefoxitin and inactivation rates for tazobactam.Impacts of Penicillin Binding Protein 2 Inactivation on β-Lactamase Expression and Muropeptide Profile in Stenotrophomonas maltophilia.Targeting the permeability barrier and peptidoglycan recycling pathways to disarm Pseudomonas aeruginosa against the innate immune system.Synergistic activity of fosfomycin, β-lactams and peptidoglycan recycling inhibition against Pseudomonas aeruginosa.Blocking peptidoglycan recycling in Pseudomonas aeruginosa attenuates intrinsic resistance to fosfomycin.Protonation states of active-site lysines of penicillin-binding protein 6 from Escherichia coli and the mechanistic implications.Role of Pseudomonas aeruginosa low-molecular-mass penicillin-binding proteins in AmpC expression, β-lactam resistance, and peptidoglycan structure.Changes to its peptidoglycan-remodeling enzyme repertoire modulate β-lactam resistance in Pseudomonas aeruginosaThe Pseudomonas aeruginosa CreBC two-component system plays a major role in the response to β-lactams, fitness, biofilm growth, and global regulation.Involvement of mutation in ampD I, mrcA, and at least one additional gene in β-lactamase hyperproduction in Stenotrophomonas maltophilia.N-acetylglucosaminidases from CAZy family GH3 are really glycoside phosphorylases, thereby explaining their use of histidine as an acid/base catalyst in place of glutamic acidDiversity and regulation of intrinsic β-lactamases from non-fermenting and other Gram-negative opportunistic pathogens.Deciphering the Nature of Enzymatic Modifications of Bacterial Cell Walls.From Genome to Proteome to Elucidation of Reactions for All Eleven Known Lytic Transglycosylases from Pseudomonas aeruginosa.
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Providing β-lactams a helping hand: targeting the AmpC β-lactamase induction pathway.
description
article científic
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article scientifique
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articol științific
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articolo scientifico
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artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
Providing β-lactams a helping hand: targeting the AmpC β-lactamase induction pathway.
@en
Providing β-lactams a helping hand: targeting the AmpC β-lactamase induction pathway.
@nl
type
label
Providing β-lactams a helping hand: targeting the AmpC β-lactamase induction pathway.
@en
Providing β-lactams a helping hand: targeting the AmpC β-lactamase induction pathway.
@nl
prefLabel
Providing β-lactams a helping hand: targeting the AmpC β-lactamase induction pathway.
@en
Providing β-lactams a helping hand: targeting the AmpC β-lactamase induction pathway.
@nl
P2860
P356
P1433
P1476
Providing β-lactams a helping hand: targeting the AmpC β-lactamase induction pathway
@en
P2093
Antonio Oliver
P2860
P304
P356
10.2217/FMB.11.128
P577
2011-12-01T00:00:00Z