Sphingosine 1-phosphate signalling in cancer. - Wikidata - wikimedia - TriplyDB

Sphingosine 1-phosphate signalling in cancer.

Sphingosine 1-phosphate signalling in cancer.

http://www.wikidata.org/entity/Q37977171

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Atheroprotective role of high-density lipoprotein (HDL)-associated sphingosine-1-phosphate (S1P)Sphingosine kinase 1 is a reliable prognostic factor and a novel therapeutic target for uterine cervical cancer.Comparative expression study of the endo-G protein coupled receptor (GPCR) repertoire in human glioblastoma cancer stem-like cells, U87-MG cells and non malignant cells of neural origin unveils new potential therapeutic targets Transforming Sphingosine Kinase 1 Inhibitors into Dual and Sphingosine Kinase 2 Selective Inhibitors: Design, Synthesis, and in Vivo Activity.Structure-activity relationship studies and in vivo activity of guanidine-based sphingosine kinase inhibitors: discovery of SphK1- and SphK2-selective inhibitors.Sphingosine kinase 1: A novel independent prognosis biomarker in hepatocellular carcinoma.microRNA-148a dysregulation discriminates poor prognosis of hepatocellular carcinoma in association with USP4 overexpression.Novel lysophosphoplipid receptors: their structure and function.microRNA-148a inhibits hepatocellular carcinoma cell invasion by targeting sphingosine-1-phosphate receptor 1 Extracellular sphingosine-1-phosphate: a novel actor in human glioblastoma stem cell survival Switching the sphingolipid rheostat in the treatment of diabetes and cancer comorbidity from a problem to an advantage.Sphingosine Kinase 2 and Ceramide Transport as Key Targets of the Natural Flavonoid Luteolin to Induce Apoptosis in Colon Cancer Cells Shaping the landscape: metabolic regulation of S1P gradients.Aldo-keto Reductase Family 1 Member B 10 Mediates Liver Cancer Cell Proliferation through Sphingosine-1-Phosphate.Aberrant expression of the S1P regulating enzymes, SPHK1 and SGPL1, contributes to a migratory phenotype in OSCC mediated through S1PR2.Analysis of aggregated cell-cell statistical distances within pathways unveils therapeutic-resistance mechanisms in circulating tumor cells.Plasma sphingolipids and lung cancer: a population-based, nested case-control study.Antitumor effect of the novel sphingosine kinase 2 inhibitor ABC294640 is enhanced by inhibition of autophagy and by sorafenib in human cholangiocarcinoma cells.Dynamic Cross Talk between S1P and CXCL12 Regulates Hematopoietic Stem Cells Migration, Development and Bone Remodeling Sphingosine 1-Phosphate Receptor Modulators and Drug Discovery.Sphingosine kinase 1 is a potential therapeutic target for nasopharyngeal carcinoma.Sphingosine-1-phosphate receptor 1 reporter mice reveal receptor activation sites in vivo.Bioactive lysophospholipids: role in regulation of aqueous humor outflow and intraocular pressure in the context of pathobiology and therapy of glaucoma.Cerebrovascular Angiogenic Reprogramming upon LRP1 Repression: Impact on Sphingosine-1-Phosphate-Mediated Signaling in Brain Endothelial Cell Chemotactism.Overexpression of SphK1 enhances cell proliferation and invasion in triple-negative breast cancer via the PI3K/AKT signaling pathway.Targeting sphingosine-1-phosphate signaling for cancer therapy.Assessing the ligand selectivity of sphingosine kinases using molecular dynamics and MM-PBSA binding free energy calculations.Implication of sphingosine-1-phosphate signaling in diseases: molecular mechanism and therapeutic strategies.Hispidulin suppresses tumor growth and metastasis in renal cell carcinoma by modulating ceramide-sphingosine 1-phosphate rheostat.Clinical Impact of Sphingosine-1-Phosphate in Breast Cancer."Dicing and Splicing" Sphingosine Kinase and Relevance to Cancer.New insights on the Intrinsic, Pro-Apoptotic Effect of IGFB3 in Breast Cancer.Unexpected profile of sphingolipid contents in blood and bone marrow plasma collected from patients diagnosed with acute myeloid leukemia.Predictive and prognostic value of sphingosine kinase 1 expression in patients with invasive ductal carcinoma of the breast.Classification of sphingosine kinase inhibitors using counter propagation artificial neural networks: A systematic route for designing selective SphK inhibitors.TGF-β/SMAD3 Pathway Stimulates Sphingosine-1 Phosphate Receptor 3 Expression: IMPLICATION OF SPHINGOSINE-1 PHOSPHATE RECEPTOR 3 IN LUNG ADENOCARCINOMA PROGRESSION.Hispidulin mediates apoptosis in human renal cell carcinoma by inducing ceramide accumulation.Evaluation of commercial antibodies against human sphingosine-1-phosphate receptor 1.LRIG1 modulates aggressiveness of head and neck cancers by regulating EGFR-MAPK-SPHK1 signaling and extracellular matrix remodeling.Sphingosine-1-phosphate receptors and innate immunity.

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Sphingosine 1-phosphate signalling in cancer.

http://www.wikidata.org/entity/Q37977171

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Sphingosine 1-phosphate signalling in cancer.

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Sphingosine 1-phosphate signalling in cancer.

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Sphingosine 1-phosphate signalling in cancer.

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Sphingosine 1-phosphate signalling in cancer.

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Sphingosine 1-phosphate signalling in cancer.

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Sphingosine 1-phosphate signalling in cancer.

@nl

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Biochemical Society Transactions

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Sphingosine 1-phosphate signalling in cancer.

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P2093

Francesca Tonelli

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Jaclyn S Long

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Joanne Edwards

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Keng Gat Lim

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Nigel J Pyne

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Susan Pyne

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P2860

Tumor cell invasion of collagen matrices requires coordinate lipid agonist-induced G-protein and membrane-type matrix metalloproteinase-1-dependent signaling

Guanine nucleotides regulate sphingosine kinase 1 activation by eukaryotic elongation factor 1A and provide a mechanism for eEF1A-associated oncogenesis

Sphingosine-1-phosphate lyase potentiates apoptosis via p53- and p38-dependent pathways and is down-regulated in colon cancer

The immunosuppressant drug FTY720 inhibits cytosolic phospholipase A2 independently of sphingosine-1-phosphate receptors

Role of human sphingosine-1-phosphate phosphatase 1 in the regulation of intra- and extracellular sphingosine-1-phosphate levels and cell viability

A molecular signature of metastasis in primary solid tumors

Expression profiling the temperature-dependent amphibian response to infection by Batrachochytrium dendrobatidis.

Sphingosine 1-phosphate signalling in mammalian cells.

Sphingosine kinase 1 induces tolerance to human epidermal growth factor receptor 2 and prevents formation of a migratory phenotype in response to sphingosine 1-phosphate in estrogen receptor-positive breast cancer cells.

Sphingosine 1-phosphate and cancer.

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94-100

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scholarly article

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10.1042/BST20110602

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1

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40

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2012-02-01T00:00:00Z

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22260672

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