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The chemokine superfamily revisitedThe hematopoietic chemokine CXCL12 promotes integration of human endothelial colony forming cell-derived cells into immature vessel networksSequential administration of the high affinity CXCR4 antagonist BKT140 promotes megakaryopoiesis and platelet production.SDF and GABA interact to regulate axophilic migration of GnRH neurons.Insights into the mechanism of inhibition of CXCR4: identification of Piperidinylethanamine analogs as anti-HIV-1 inhibitors.Bivalent ligands targeting chemokine receptor dimerization: molecular design and functional studies.IL-24 inhibits lung cancer cell migration and invasion by disrupting the SDF-1/CXCR4 signaling axisEZH2-mediated loss of miR-622 determines CXCR4 activation in hepatocellular carcinoma.Molecular targets of androgen signaling that characterize skeletal muscle recovery and regeneration.CXCL12 genetic variants as prognostic markers in nasopharyngeal carcinoma.Intracellular CXCR4⁺ cell targeting with T22-empowered protein-only nanoparticles.Chemokine 25-induced signaling suppresses colon cancer invasion and metastasis.HuR-targeted nanotherapy in combination with AMD3100 suppresses CXCR4 expression, cell growth, migration and invasion in lung cancer.CXCR4/CXCL12 axis in non small cell lung cancer (NSCLC) pathologic roles and therapeutic potential.Whole Exome- and mRNA-Sequencing of an AT/RT Case Reveals Few Somatic Mutations and Several Deregulated Signalling Pathways in the Context of SMARCB1 Deficiency.CXCR4 Protein Epitope Mimetic Antagonist POL5551 Disrupts Metastasis and Enhances Chemotherapy Effect in Triple-Negative Breast Cancer.CXCR4/CXCL12 mediate autocrine cell- cycle progression in NF1-associated malignant peripheral nerve sheath tumors.Chemokines and their receptors in lung cancer progression and metastasis.Trial Watch-Small molecules targeting the immunological tumor microenvironment for cancer therapy.RNAi targeting CXCR4 inhibits proliferation and invasion of esophageal carcinoma cells.Emerging targets in cancer management: role of the CXCL12/CXCR4 axis.Antitumour activity of the recombination polypeptide GST-NT21MP is mediated by inhibition of CXCR4 pathway in breast cancer.Induced interleukin-33 expression enhances the tumorigenic activity of rat glioma cells.N-terminal polypeptide derived from vMIP-II exerts its antitumor activity by inhibiting the CXCR4 pathway in human gliomaImaging agents for the chemokine receptor 4 (CXCR4).Molecular mechanisms of curcumin action: gene expression.Molecular imaging of chemokine receptor CXCR4.The Spiegelmer NOX-A12, a novel CXCL12 inhibitor, interferes with chronic lymphocytic leukemia cell motility and causes chemosensitizationOncogenic roles and drug target of CXCR4/CXCL12 axis in lung cancer and cancer stem cell.Glycosaminoglycan silencing by engineered CXCL12 variants.Interaction of chemokine receptor CXCR4 in monomeric and dimeric state with its endogenous ligand CXCL12: coarse-grained simulations identify differences.Discovery of tetrahydroisoquinoline-based CXCR4 antagonists.[177Lu]pentixather: Comprehensive Preclinical Characterization of a First CXCR4-directed Endoradiotherapeutic Agent.Discovery of novel N-aryl piperazine CXCR4 antagonists.Changes in circulating endothelial progenitor cells predict responses of multiple myeloma patients to treatment with bortezomib and dexamethasone.The CXCR4 inhibitor BL-8040 induces the apoptosis of AML blasts by downregulating ERK, BCL-2, MCL-1 and cyclin-D1 via altered miR-15a/16-1 expression.Inhibition of SDF-1-induced migration of oncogene-driven myeloid leukemia by the L-RNA aptamer (Spiegelmer), NOX-A12, and potentiation of tyrosine kinase inhibition.Screening of cancer tissue arrays identifies CXCR4 on adrenocortical carcinoma: correlates with expression and quantification on metastases using 64Cu-plerixafor PET.Multiple myeloma: New surface antigens for the characterization of plasma cells in the era of novel agents.Imaging CXCR4 Expression with (99m)Tc-Radiolabeled Small-Interference RNA in Experimental Human Breast Cancer Xenografts.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Development of novel CXCR4-based therapeutics.
@en
Development of novel CXCR4-based therapeutics.
@nl
type
label
Development of novel CXCR4-based therapeutics.
@en
Development of novel CXCR4-based therapeutics.
@nl
prefLabel
Development of novel CXCR4-based therapeutics.
@en
Development of novel CXCR4-based therapeutics.
@nl
P2093
P2860
P1476
Development of novel CXCR4-based therapeutics.
@en
P2093
P2860
P304
P356
10.1517/13543784.2012.656197
P407
P577
2012-01-28T00:00:00Z