Disease-associated patterns of disomic chromosomes in hyperhaploid neoplasms.
about
Retained heterodisomy is associated with high gene expression in hyperhaploid inflammatory leiomyosarcoma.Genetic and epigenetic characterization of hypodiploid acute lymphoblastic leukemia.Malignant mesenchymal tumors of the uterus - time to advocate a genetic classification.Comprehensive genetic analysis of a pediatric pleomorphic myxoid liposarcoma reveals near-haploidization and loss of the RB1 gene.Hyperhaploidy is a novel high-risk cytogenetic subgroup in multiple myeloma.Array-based comparative genomic hybridization detects copy number variations with prognostic relevance in 80% of ALL with normal karyotype or failed chromosome analysis.Acute lymphoblastic leukemia with low hypodiploid/near triploid karyotype is a specific clinical entity and exhibits a very high TP53 mutation frequency of 93%.Loss of chromosomes is the primary event in near-haploid and low-hypodiploid acute lymphoblastic leukemia.Inflammatory leiomyosarcoma is a distinct tumor characterized by near-haploidization, few somatic mutations, and a primitive myogenic gene expression signature.Near-haploidization significantly associates with oncocytic adrenocortical, thyroid, and parathyroid tumors but not with mitochondrial DNA mutations.
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P2860
Disease-associated patterns of disomic chromosomes in hyperhaploid neoplasms.
description
article científic
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article scientifique
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articol științific
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articolo scientifico
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artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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artículo científico
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name
Disease-associated patterns of disomic chromosomes in hyperhaploid neoplasms.
@en
Disease-associated patterns of disomic chromosomes in hyperhaploid neoplasms.
@nl
type
label
Disease-associated patterns of disomic chromosomes in hyperhaploid neoplasms.
@en
Disease-associated patterns of disomic chromosomes in hyperhaploid neoplasms.
@nl
prefLabel
Disease-associated patterns of disomic chromosomes in hyperhaploid neoplasms.
@en
Disease-associated patterns of disomic chromosomes in hyperhaploid neoplasms.
@nl
P2093
P2860
P356
P1476
Disease-associated patterns of disomic chromosomes in hyperhaploid neoplasms.
@en
P2093
Bertil Johansson
Felix Mitelman
Nils Mandahl
P2860
P304
P356
10.1002/GCC.21947
P577
2012-02-15T00:00:00Z