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Cellular Pathways in Response to Ionizing Radiation and Their Targetability for Tumor RadiosensitizationDNA Damage Signalling and Repair Inhibitors: The Long-Sought-After Achilles' Heel of CancerPathway-specific engineered mouse allograft models functionally recapitulate human serous epithelial ovarian cancerRAD50 targeting impairs DNA damage response and sensitizes human breast cancer cells to cisplatin therapyTargeting DNA repair pathways for cancer treatment: what's new?NEK8 regulates DNA damage-induced RAD51 foci formation and replication fork protectionR-loops and genomic instability in Bre1 (RNF20/40)-deficient cells.Triapine potentiates platinum-based combination therapy by disruption of homologous recombination repair.HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanatesRadioprotection of normal tissue cells.Embracing synthetic lethality of novel anticancer therapies.Regulation of recombination and genomic maintenance.Molecular inhibitors of DNA repair: searching for the ultimate tumor killing weapon.miR-15a/miR-16 down-regulates BMI1, impacting Ub-H2A mediated DNA repair and breast cancer cell sensitivity to doxorubicinDNA repair of myeloma plasma cells correlates with clinical outcome: the effect of the nonhomologous end-joining inhibitor SCR7.RAD51 as a potential surrogate marker for DNA repair capacity in solid malignancies.Rosiglitazone enhances radiosensitivity by inhibiting repair of DNA damage in cervical cancer cells.Targeting DNA repair and replication stress in the treatment of ovarian cancer.The purine scaffold Hsp90 inhibitor PU-H71 sensitizes cancer cells to heavy ion radiation by inhibiting DNA repair by homologous recombination and non-homologous end joining.Use of the XRCC2 promoter for in vivo cancer diagnosis and therapy.Synthetic lethal targeting of RNF20 through PARP1 silencing and inhibition.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
Inhibiting homologous recombination for cancer therapy.
@en
Inhibiting homologous recombination for cancer therapy.
@nl
type
label
Inhibiting homologous recombination for cancer therapy.
@en
Inhibiting homologous recombination for cancer therapy.
@nl
prefLabel
Inhibiting homologous recombination for cancer therapy.
@en
Inhibiting homologous recombination for cancer therapy.
@nl
P2093
P2860
P356
P1476
Inhibiting homologous recombination for cancer therapy.
@en
P2093
J Martin Brown
John C Game
Sophia B Chernikova
P2860
P356
10.4161/CBT.13.2.18872
P577
2012-01-01T00:00:00Z