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Alzheimer's Disease: Mechanism and Approach to Cell TherapyThe associations between Parkinson's disease and cancer: the plot thickensInsights into the physiological function of the β-amyloid precursor protein: beyond Alzheimer's diseaseAmyloid β precursor protein as a molecular target for amyloid β--induced neuronal degeneration in Alzheimer's diseaseGenetic markers in biological fluids for aging-related major neurocognitive disorderAmyloid-Beta Induced Changes in Vesicular Transport of BDNF in Hippocampal NeuronsMultiplex assay for live-cell monitoring of cellular fates of amyloid-β precursor protein (APP)APP is cleaved by Bace1 in pre-synaptic vesicles and establishes a pre-synaptic interactome, via its intracellular domain, with molecular complexes that regulate pre-synaptic vesicles functionsFoxO mediates APP-induced AICD-dependent cell death.LRP1 Modulates APP Intraneuronal Transport and Processing in Its Monomeric and Dimeric StateAerobic exercise improves quality of life, psychological well-being and systemic inflammation in subjects with Alzheimer's disease.Comparative analysis of single and combined APP/APLP knockouts reveals reduced spine density in APP-KO mice that is prevented by APPsα expression.Genome-wide, high-content siRNA screening identifies the Alzheimer's genetic risk factor FERMT2 as a major modulator of APP metabolism.A vaccine with Aβ oligomer-specific mimotope attenuates cognitive deficits and brain pathologies in transgenic mice with Alzheimer's diseaseThe structural network of Interleukin-10 and its implications in inflammation and cancerAmyloid precursor protein (APP)/APP-like protein 2 (APLP2) expression is required to initiate endosome-nucleus-autophagosome trafficking of glypican-1-derived heparan sulfateThe FAM3 superfamily member ILEI ameliorates Alzheimer's disease-like pathology by destabilizing the penultimate amyloid-β precursor.A comparative evaluation of treatments with 17β-estradiol and its brain-selective prodrug in a double-transgenic mouse model of Alzheimer's diseaseAPP as a Protective Factor in Acute Neuronal Insults.Computational prediction of protein interactions related to the invasion of erythrocytes by malarial parasitesY682G Mutation of Amyloid Precursor Protein Promotes Endo-Lysosomal Dysfunction by Disrupting APP-SorLA Interaction.Amyloid-β precursor protein: Multiple fragments, numerous transport routes and mechanismsDepletion of Amyloid Precursor Protein (APP) causes G0 arrest in non-small cell lung cancer (NSCLC) cells.Presenilins and γ-secretase: structure, function, and role in Alzheimer Disease.Deciphering Alzheimer disease.Holo-APP and G-protein-mediated signaling are required for sAPPα-induced activation of the Akt survival pathway.Neurodegeneration in Autoimmune Optic Neuritis Is Associated with Altered APP Cleavage in Neurons and Up-Regulation of p53Astrocytes regulate α-secretase-cleaved soluble amyloid precursor protein secretion in neuronal cells: Involvement of group IIA secretory phospholipase A2Synaptotagmins interact with APP and promote Aβ generation.Protein post-translational modifications and misfolding: new concepts in heart failure.The keystone of Alzheimer pathogenesis might be sought in Aβ physiologyAltered Innate Immune and Glial Cell Responses to Inflammatory Stimuli in Amyloid Precursor Protein Knockout Mice.Region-Specific Differences in Amyloid Precursor Protein Expression in the Mouse Hippocampus.APP and APLP2 interact with the synaptic release machinery and facilitate transmitter release at hippocampal synapses.PP2A methylation controls sensitivity and resistance to β-amyloid-induced cognitive and electrophysiological impairments.APP Receptor? To Be or Not To Be.A novel high throughput 1536-well Notch1 γ -secretase AlphaLISA assayFinding novel distinctions between the sAPPα-mediated anabolic biochemical pathways in Autism Spectrum Disorder and Fragile X Syndrome plasma and brain tissueAmyloid Precursor-Like Protein 2 deletion-induced retinal synaptopathy related to congenital stationary night blindness: structural, functional and molecular characteristicsLoss of presenilin function is associated with a selective gain of APP function.
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P2860
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Physiological functions of APP family proteins.
@en
Physiological functions of APP family proteins.
@nl
type
label
Physiological functions of APP family proteins.
@en
Physiological functions of APP family proteins.
@nl
prefLabel
Physiological functions of APP family proteins.
@en
Physiological functions of APP family proteins.
@nl
P2860
P1476
Physiological functions of APP family proteins.
@en
P2093
Ulrike C Müller
P2860
P304
P356
10.1101/CSHPERSPECT.A006288
P577
2012-02-01T00:00:00Z