Ligand binding assays in the 21st century laboratory: recommendations for characterization and supply of critical reagents.
about
Generation and characterization of a unique reagent that recognizes a panel of recombinant human monoclonal antibody therapeutics in the presence of endogenous human IgGToward sensitive and accurate analysis of antibody biotherapeutics by liquid chromatography coupled with mass spectrometry.Conjugated critical reagent characterization for ligand-binding assays: using MALDI-TOF-MS as an orthogonal tool to assess assay performance.Pre-existing Antibody: Biotherapeutic Modality-Based Review.Storage Conditions of Conjugated Reagents Can Impact Results of Immunogenicity Assays.Recommendations and best practices for reference standards and reagents used in bioanalytical method validation.Life cycle management of critical ligand-binding reagents.Current industrial practices and regulatory requirements to assess analyte and reagent stability using ligand-binding assays.Addressing matrix effects in ligand-binding assays through the use of new reagents and technology.Ligand binding assay critical reagents and their stability: recommendations and best practices from the Global Bioanalysis Consortium Harmonization Team.Immunogenicity of antibody drug conjugates: bioanalytical methods and monitoring strategy for a novel therapeutic modality.Ligand binding assays in the 21st century laboratory-a call for change.Stability assessment in ligand-binding assays: a critical parameter for data integrity.How the bioanalytical scientist plays a key role in interdisciplinary project teams in the development of biotherapeutics - a reflection of the European Bioanalysis Forum.Development of an LC-MS/MS method with protein G purification strategy for quantifying bevacizumab in human plasma.Conference report: moving forward together: "we are making progress".Best practice recommendations for the transfer of cell-based assays for the measurement of neutralizing anti-drug antibodies.Immunogenicity considerations for antibody-drug conjugates: a focus on neutralizing antibody assays.Development of a plug and play ImmunoPCR technique for the analysis of biomolecules.Conference report: Bioanalysis highlights from the 2012 American Association of Pharmaceutical Scientists National Biotechnology Conference.Characterization of labeled reagents in ligand-binding assays by a surface plasmon resonance biosensor.Validation and life-cycle management of a quantitative ligand-binding assay for the measurement of Nulojix(®), a CTLA-4-Fc fusion protein, in renal and liver transplant patients.Development and characterization of antibody reagents to assess anti-PEG IgG antibodies in clinical samples.Strategic approaches for assessment and minimization of matrix effect in ligand-binding assays.
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P2860
Ligand binding assays in the 21st century laboratory: recommendations for characterization and supply of critical reagents.
description
article científic
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article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
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artikull shkencor
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artículo científico
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name
Ligand binding assays in the 2 ...... d supply of critical reagents.
@en
Ligand binding assays in the 2 ...... d supply of critical reagents.
@nl
type
label
Ligand binding assays in the 2 ...... d supply of critical reagents.
@en
Ligand binding assays in the 2 ...... d supply of critical reagents.
@nl
prefLabel
Ligand binding assays in the 2 ...... d supply of critical reagents.
@en
Ligand binding assays in the 2 ...... d supply of critical reagents.
@nl
P2093
P2860
P1433
P1476
Ligand binding assays in the 2 ...... d supply of critical reagents.
@en
P2093
Adrienne Clements Egan
Afshin Safavi
Denise M O'Hara
Frank P Spriggs
Jeannine Keefe
Joel Usansky
John Kenney
Julie TerWee
Murli Krishna
Valerie Theobald
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P2888
P304
P356
10.1208/S12248-012-9334-9
P407
P577
2012-03-14T00:00:00Z
P5875
P6179
1043256997