Microarray, qPCR, and KCNJ5 sequencing of aldosterone-producing adenomas reveal differences in genotype and phenotype between zona glomerulosa- and zona fasciculata-like tumors.
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Intracellular Molecular Differences in Aldosterone- Compared to Cortisol-Secreting Adrenal Cortical AdenomasGenetics of Aldosterone-Producing Adenoma in Korean PatientsPrimary Aldosteronism: Changing Definitions and New Concepts of Physiology and Pathophysiology Both Inside and Outside the Kidney.Small-Conductance Ca2+-Activated Potassium Channels Negatively Regulate Aldosterone Secretion in Human Adrenocortical Cells.Role of voltage-gated calcium channels in the regulation of aldosterone production from zona glomerulosa cells of the adrenal cortex.Overview of the genetic determinants of primary aldosteronism.Minireview: potassium channels and aldosterone dysregulation: is primary aldosteronism a potassium channelopathy?Physiological and Pathological Roles in Human Adrenal of the Glomeruli-Defining Matrix Protein NPNT (Nephronectin).Adrenal CYP11B1/2 expression in primary aldosteronism: immunohistochemical analysis using novel monoclonal antibodies.Different expression of 11β-hydroxylase and aldosterone synthase between aldosterone-producing microadenomas and macroadenomas.Understanding primary aldosteronism: impact of next generation sequencing and expression profiling.DACH1, a zona glomerulosa selective gene in the human adrenal, activates transforming growth factor-β signaling and suppresses aldosterone secretionTwo-pore domain potassium channels in the adrenal cortex.LGR5 Activates Noncanonical Wnt Signaling and Inhibits Aldosterone Production in the Human AdrenalImmunohistochemical, genetic and clinical characterization of sporadic aldosterone-producing adenomas.Aldosterone-stimulating somatic gene mutations are common in normal adrenal glandsPrevalence and characterization of somatic mutations in Chinese aldosterone-producing adenoma patients.Pregnancy, Primary Aldosteronism, and Adrenal CTNNB1 Mutations.Activating mutations in CTNNB1 in aldosterone producing adenomas.Molecular Heterogeneity in Aldosterone-Producing Adenomas3β-Hydroxysteroid dehydrogenase isoforms in human aldosterone-producing adenoma.Novel somatic mutations in primary hyperaldosteronism are related to the clinical, radiological and pathological phenotypeMutated KCNJ5 activates the acute and chronic regulatory steps in aldosterone productionTranscriptome Pathway Analysis of Pathological and Physiological Aldosterone-Producing Human Tissues.Sodium deficiency regulates rat adrenal zona glomerulosa gene expression.Role of KCNJ5 in familial and sporadic primary aldosteronism.Steroidogenesis-adrenal cell signal transduction.Histopathological and genetic characterization of aldosterone-producing adenomas with concurrent subclinical cortisol hypersecretion: a case series.Subtype Diagnosis of Primary Aldosteronism: Is Adrenal Vein Sampling Always Necessary?Of channels and pumps: different ways to boost the aldosterone?WNT/β-catenin signalling is activated in aldosterone-producing adenomas and controls aldosterone production.Intratumoral heterogeneity of steroidogenesis in aldosterone-producing adenoma revealed by intensive double- and triple-immunostaining for CYP11B2/B1 and CYP17.Transcription controls growth, cell kinetics and cholesterol supply to sustain ACTH responses.Genetic mechanisms of human hypertension and their implications for blood pressure physiology.Primary Aldosteronism: unnecessary complexity in definition and diagnosis as a barrier to wider clinical care.Disordered zonal and cellular CYP11B2 enzyme expression in familial hyperaldosteronism type 3.The Many Faces of Primary Aldosteronism and Cushing Syndrome: A Reflection of Adrenocortical Tumor Heterogeneity.Comparative Genomics and Transcriptome Profiling in Primary Aldosteronism.
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P2860
Microarray, qPCR, and KCNJ5 sequencing of aldosterone-producing adenomas reveal differences in genotype and phenotype between zona glomerulosa- and zona fasciculata-like tumors.
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article científic
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article scientifique
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articol științific
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articolo scientifico
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artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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Microarray, qPCR, and KCNJ5 se ...... zona fasciculata-like tumors.
@en
Microarray, qPCR, and KCNJ5 se ...... zona fasciculata-like tumors.
@nl
type
label
Microarray, qPCR, and KCNJ5 se ...... zona fasciculata-like tumors.
@en
Microarray, qPCR, and KCNJ5 se ...... zona fasciculata-like tumors.
@nl
prefLabel
Microarray, qPCR, and KCNJ5 se ...... zona fasciculata-like tumors.
@en
Microarray, qPCR, and KCNJ5 se ...... zona fasciculata-like tumors.
@nl
P2093
P356
P1476
Microarray, qPCR, and KCNJ5 se ...... zona fasciculata-like tumors.
@en
P2093
Alison Marker
Brian Y H Lam
Elena A B Azizan
Gary J Hoffman
Jennifer Clarke
Junhua Zhou
Lisa Happerfield
Morris J Brown
Rhoda E Kuc
Stephen J Newhouse
P304
P356
10.1210/JC.2011-2965
P407
P577
2012-03-22T00:00:00Z