Molecular mechanisms and potential functions of histone demethylases.
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The histone demethylase Jarid1b ensures faithful mouse development by protecting developmental genes from aberrant H3K4me3PARP1-dependent recruitment of KDM4D histone demethylase to DNA damage sites promotes double-strand break repairLSD1/CoREST is an allosteric nanoscale clamp regulated by H3-histone-tail molecular recognition.Histone demethylases in chromatin biology and beyondHistone lysine demethylases in Drosophila melanogasterEpigenetic regulation by histone demethylases in hypoxiaInflammation and Nutritional Science for Programs/Policies and Interpretation of Research Evidence (INSPIRE).High-throughput screening to identify inhibitors of lysine demethylasesThe Interplay between Chromatin and Transcription Factor Networks during B Cell Development: Who Pulls the Trigger First?Mechanisms of epigenetic regulation of leukemia onset and progressionAn unexpected journey: lysine methylation across the proteomeThe role of histone demethylases in cancer therapyIDH1/2 mutations target a key hallmark of cancer by deregulating cellular metabolism in gliomaKDM4/JMJD2 histone demethylases: epigenetic regulators in cancer cellsChromatin signatures of cancerEpigenetic regulation of inducible gene expression in the immune systemSingle molecule and single cell epigenomics.Cellular defense against latent colonization foiled by human cytomegalovirus UL138 protein.8-Substituted Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase InhibitorsHuman UTY(KDM6C) Is a Male-specific N -Methyl Lysyl DemethylaseAn inhibitor of KDM5 demethylases reduces survival of drug-tolerant cancer cellsStructural analysis of human KDM5B guides histone demethylase inhibitor developmentCell-based assays to support the profiling of small molecules with histone methyltransferase and demethylase modulatory activityUndercover: gene control by metabolites and metabolic enzymesHistone demethylase lysine demethylase 5B in development and cancerComputer-aided Molecular Design of Compounds Targeting Histone Modifying EnzymesKDM1 class flavin-dependent protein lysine demethylasesNDUFAF7 methylates arginine 85 in the NDUFS2 subunit of human complex IBase excision repair facilitates a functional relationship between Guanine oxidation and histone demethylationProtein complex interactor analysis and differential activity of KDM3 subfamily members towards H3K9 methylationHistone demethylase jumonji AT-rich interactive domain 1B (JARID1B) controls mammary gland development by regulating key developmental and lineage specification genesSynergistic re-activation of epigenetically silenced genes by combinatorial inhibition of DNMTs and LSD1 in cancer cellsKdmB, a Jumonji Histone H3 Demethylase, Regulates Genome-Wide H3K4 Trimethylation and Is Required for Normal Induction of Secondary Metabolism in Aspergillus nidulansKDM4C, a H3K9me3 Histone Demethylase, is Involved in the Maintenance of Human ESCC-Initiating Cells by Epigenetically Enhancing SOX2 ExpressionEpigenetic regulation in the inner ear and its potential roles in development, protection, and regeneration.Modulation of epigenetic targets for anticancer therapy: clinicopathological relevance, structural data and drug discovery perspectivesRapid changes in histone deacetylases and inflammatory gene expression in expert meditators.Genome-wide analysis of histone modifiers in tomato: gaining an insight into their developmental roles.Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells.Phf8 loss confers resistance to depression-like and anxiety-like behaviors in mice
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Molecular mechanisms and potential functions of histone demethylases.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Molecular mechanisms and potential functions of histone demethylases.
@en
Molecular mechanisms and potential functions of histone demethylases.
@nl
type
label
Molecular mechanisms and potential functions of histone demethylases.
@en
Molecular mechanisms and potential functions of histone demethylases.
@nl
prefLabel
Molecular mechanisms and potential functions of histone demethylases.
@en
Molecular mechanisms and potential functions of histone demethylases.
@nl
P356
P1476
Molecular mechanisms and potential functions of histone demethylases.
@en
P2093
Susanne Marije Kooistra
P2888
P304
P356
10.1038/NRG3219
P577
2012-04-04T00:00:00Z