about
Parkinsonism-associated protein DJ-1/Park7 is a major protein deglycase that repairs methylglyoxal- and glyoxal-glycated cysteine, arginine, and lysine residuesHydrogen peroxide - production, fate and role in redox signaling of tumor cellsRedox control of microglial function: molecular mechanisms and functional significanceTrxR1 as a potent regulator of the Nrf2-Keap1 response systemRedox regulation of store-operated Ca2+ entryParadoxical Roles of Antioxidant Enzymes: Basic Mechanisms and Health ImplicationsThe cysteine proteomeIndolin-2-one compounds targeting thioredoxin reductase as potential anticancer drug leadsAn overview of mechanisms of redox signaling.Cross-linking of thioredoxin reductase by the sulfur mustard analogue mechlorethamine (methylbis(2-chloroethyl)amine) in human lung epithelial cells and rat lung: selective inhibition of disulfide reduction but not redox cycling.Carbamoylating activity associated with the activation of the antitumor agent laromustine inhibits angiogenesis by inducing ASK1-dependent endothelial cell deathTubular p53 regulates multiple genes to mediate AKIHuman thioredoxin 2 deficiency impairs mitochondrial redox homeostasis and causes early-onset neurodegeneration.Abrogated thioredoxin system causes increased sensitivity to TNF-α-induced apoptosis via enrichment of p-ERK 1/2 in the nucleus.Thioredoxin-deficient mice, a novel phenotype sensitive to ambient air and hypersensitive to hyperoxia-induced lung injury.Deletion of thioredoxin interacting protein (TXNIP) augments hyperoxia-induced vaso-obliteration in a mouse model of oxygen induced-retinopathy.A comparative proteomic study of Homoharringtonine-induced apoptosis in leukemia K562 cells.Thioredoxin-2 Modulates Neuronal Programmed Cell Death in the Embryonic Chick Spinal Cord in Basal and Target-Deprived ConditionsRedox effects and cytotoxic profiles of MJ25 and auranofin towards malignant melanoma cells.Thioredoxin Inhibitors Attenuate Platelet Function and Thrombus Formation.Thidoredxin-2 overexpression fails to rescue chronic high calorie diet induced hippocampal dysfunction.Master redox regulator Trx1 upregulates SMYD1 & modulates lysine methylation.B5, a thioredoxin reductase inhibitor, induces apoptosis in human cervical cancer cells by suppressing the thioredoxin system, disrupting mitochondrion-dependent pathways and triggering autophagy.Thioredoxin 1 protects astrocytes from oxidative stress by maintaining peroxiredoxin activity.EM23, A Natural Sesquiterpene Lactone from Elephantopus mollis, Induces Apoptosis in Human Myeloid Leukemia Cells through Thioredoxin- and Reactive Oxygen Species-Mediated Signaling Pathways.Identification of Michael acceptor-centric pharmacophores with substituents that yield strong thioredoxin reductase inhibitory character correlated to antiproliferative activity.Curcumin prevents muscle damage by regulating NF-κB and Nrf2 pathways and improves performance: an in vivo model.Novel action and mechanism of auranofin in inhibition of vascular endothelial growth factor receptor-3-dependent lymphangiogenesis.Role of thioredoxin reductase 1 in dysplastic transformation of human breast epithelial cells triggered by chronic oxidative stressCambogin exerts anti-proliferative and pro-apoptotic effects on breast adenocarcinoma through the induction of NADPH oxidase 1 and the alteration of mitochondrial morphology and dynamicsDecreased thioredoxin-1 and increased HSP90 expression in skeletal muscle in subjects with type 2 diabetes or impaired glucose tolerance.Prognostic and diagnostic potential of isocitrate dehydrogenase 1 in esophageal squamous cell carcinoma.TIGAR knockdown radiosensitizes TrxR1-overexpressing glioma in vitro and in vivo via inhibiting Trx1 nuclear transport.Recoding the genetic code with selenocysteine.The clinical significance of isocitrate dehydrogenase 2 in esophageal squamous cell carcinoma.Chemical biology of anticancer gold(III) and gold(I) complexes.Oxidative Stress Gene Expression Profile Correlates with Cancer Patient Poor Prognosis: Identification of Crucial Pathways Might Select Novel Therapeutic Approaches.TXNIP in Metabolic Regulation: Physiological Role and Therapeutic Outlook.Cellular Redox Systems Impact the Aggregation of Cu,Zn Superoxide Dismutase Linked to Familial Amyotrophic Lateral Sclerosis.Thioredoxin Cross-Linking by Nitrogen Mustard in Lung Epithelial Cells: Formation of Multimeric Thioredoxin/Thioredoxin Reductase Complexes and Inhibition of Disulfide Reduction.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Thioredoxin system in cell death progression.
@en
type
label
Thioredoxin system in cell death progression.
@en
prefLabel
Thioredoxin system in cell death progression.
@en
P356
P1476
Thioredoxin system in cell death progression.
@en
P2093
P304
P356
10.1089/ARS.2012.4650
P577
2012-06-11T00:00:00Z