Medicinal chemistry of farnesoid X receptor ligands: from agonists and antagonists to modulators.
about
NSAIDs Ibuprofen, Indometacin, and Diclofenac do not interact with Farnesoid X Receptor.Transactivation and Coactivator Recruitment Assays for Measuring Farnesoid X Receptor Activity.Quantitative high-throughput profiling of environmental chemicals and drugs that modulate farnesoid X receptorCharacterizing ligands for farnesoid X receptor--available in vitro test systems for farnesoid X receptor modulator development.Farnesoid x receptor in human metabolism and disease: the interplay between gene polymorphisms, clinical phenotypes and disease susceptibility.Clinical significance of farnesoid X receptor expression in thyroid neoplasia.SAR studies on FXR modulators led to the discovery of the first combined FXR antagonistic/TGR5 agonistic compound.Conformational modulation of the farnesoid X receptor by prenylflavonoids: Insights from hydrogen deuterium exchange mass spectrometry (HDX-MS), fluorescence titration and molecular docking studies.Synthesis and Biological Evaluation of a Series of Bile Acid Derivatives as FXR Agonists for Treatment of NASH.Discovery of Farnesoid X Receptor Antagonists Based on a Library of Oleanolic Acid 3-O-Esters through Diverse Substituent Design and Molecular Docking Methods.
P2860
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P2860
Medicinal chemistry of farnesoid X receptor ligands: from agonists and antagonists to modulators.
description
article científic
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article scientifique
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articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
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artikull shkencor
@sq
artículo científico
@es
name
Medicinal chemistry of farneso ...... and antagonists to modulators.
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type
label
Medicinal chemistry of farneso ...... and antagonists to modulators.
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prefLabel
Medicinal chemistry of farneso ...... and antagonists to modulators.
@en
P2860
P356
P1476
Medicinal chemistry of farneso ...... and antagonists to modulators.
@en
P2093
Daniel Merk
P2860
P304
P356
10.4155/FMC.12.47
P577
2012-05-01T00:00:00Z