Maspin: molecular mechanisms and therapeutic implications.
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Maspin is not required for embryonic development or tumour suppressionCirculating DNA as biomarker in breast cancerUpregulation of maspin expression in human cervical carcinoma cells by transforming growth factor β1 through the convergence of Smad and non-Smad signaling pathways.Cytoplasmic maspin expression predicts poor prognosis of patients with soft tissue sarcomas.Serpin B5 is a CEA-interacting biomarker for colorectal cancer.Identification of an intrinsic determinant critical for maspin subcellular localization and function.Nuclear maspin expression correlates with the CpG island methylator phenotype and tumor aggressiveness in colorectal cancer.Activating transcription factor 3 is overexpressed in human glioma and its knockdown in glioblastoma cells causes growth inhibition both in vitro and in vivo.Expression and clinical significance of microRNA-21, maspin and vascular endothelial growth factor-C in bladder cancerUnexpected maspin immunoreactivity in Merkel cell carcinomamiRNA-7/21/107 contribute to HBx-induced hepatocellular carcinoma progression through suppression of maspin.Maspin enhances cisplatin chemosensitivity in bladder cancer T24 and 5637 cells and correlates with prognosis of muscle-invasive bladder cancer patients receiving cisplatin based neoadjuvant chemotherapy.Role of maspin in cancer.Tumor-suppressive maspin functions as a reactive oxygen species scavenger: importance of cysteine residues.Elevated maspin expression is associated with better overall survival in esophageal squamous cell carcinoma (ESCC).Proteolytic activation transforms heparin cofactor II into a host defense moleculeMethylation-induced silencing of maspin contributes to the proliferation of human glioma cellsNuclear IKKα mediates microRNA-7/-103/107/21 inductions to downregulate maspin expression in response to HBx overexpressionCarboxyl-terminal truncated HBx contributes to invasion and metastasis via deregulating metastasis suppressors in hepatocellular carcinoma.Temporal bone carcinoma: a first glance beyond the conventional clinical and pathological prognostic factors.Tumor suppressor maspin as a modulator of host immune response to cancer.Sulforaphane-cysteine-induced apoptosis via phosphorylated ERK1/2-mediated maspin pathway in human non-small cell lung cancer cells.Effects of Noninhibitory Serpin Maspin on the Actin Cytoskeleton: A Quantitative Image Modeling Approach.RGD and polyhistidine tumor homing peptides potentiates the action of human Maspin as an antineoplastic candidate.Ubiquitin specific peptidase 5 mediates Histidine-rich protein Hpn induced cell apoptosis in hepatocellular carcinoma through P14-P53 signaling.A Higher Angiogenin Expression is Associated With a Nonnuclear Maspin Location in Laryngeal Carcinoma.Cytoplasmic Maspin Expression Correlates with Poor Prognosis of Patients with Adenocarcinoma of the Uterine CervixExpression patterns of maspin and mutant p53 are associated with the development of gestational trophoblastic neoplasiaMaspin expression patterns differ in the invasive versus lepidic growth pattern of pulmonary adenocarcinoma.Expression of the tumour-suppressor maspin in temporal bone carcinoma.Proteomic profiling identifies markers for inflammation-related tumor-fibroblast interaction.Mammary serine protease inhibitor and CD138 immunohistochemical expression in ovarian serous and clear cell carcinomas.Cytoplasmic expression of maspin predicts unfavourable prognosis in patients with squamous cell carcinoma of the lung.Elderly patients at higher risk of laryngeal carcinoma recurrence could be identified by a panel of two biomarkers (nm23-H1 and CD105) and pN+ status.
P2860
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P2860
Maspin: molecular mechanisms and therapeutic implications.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
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artículo científico
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name
Maspin: molecular mechanisms and therapeutic implications.
@en
type
label
Maspin: molecular mechanisms and therapeutic implications.
@en
prefLabel
Maspin: molecular mechanisms and therapeutic implications.
@en
P2093
P2860
P1476
Maspin: molecular mechanisms and therapeutic implications.
@en
P2093
Elisabeth A Seftor
Mary J C Hendrix
Philip A Pemberton
Richard E B Seftor
Thomas M Bodenstine
Zhila Khalkhali-Ellis
P2860
P2888
P304
P356
10.1007/S10555-012-9361-0
P577
2012-12-01T00:00:00Z
P6179
1009999394