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Biological and therapeutic relevance of nonreplicative DNA polymerases to cancer.

Biological and therapeutic relevance of nonreplicative DNA polymerases to cancer.

http://www.wikidata.org/entity/Q38026112

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"Gate-keeper" residues and active-site rearrangements in DNA polymerase μ help discriminate non-cognate nucleotides.Requirement for transient metal ions revealed through computational analysis for DNA polymerase going in reverse.Relative Binding Free Energies of Adenine and Guanine to Damaged and Undamaged DNA in Human DNA Polymerase η: Clues for Fidelity and Overall Efficiency.Comparative Molecular Dynamics Studies of Human DNA Polymerase η.Translesion DNA polymerases in eukaryotes: what makes them tick?Cooperative motion of a key positively charged residue and metal ions for DNA replication catalyzed by human DNA Polymerase-η.Effects of Active Site Mutations on Specificity of Nucleobase Binding in Human DNA Polymerase η.Precision genome editing using synthesis-dependent repair of Cas9-induced DNA breaks.Modulating the DNA polymerase β reaction equilibrium to dissect the reverse reaction.Metal-mediated diradical tuning for DNA replication arrest via template strand scission.

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Biological and therapeutic relevance of nonreplicative DNA polymerases to cancer.

http://www.wikidata.org/entity/Q38026112

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article científic

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article scientifique

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Biological and therapeutic relevance of nonreplicative DNA polymerases to cancer.

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Biological and therapeutic relevance of nonreplicative DNA polymerases to cancer.

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Biological and therapeutic relevance of nonreplicative DNA polymerases to cancer.

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Antioxidants & Redox Signaling

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Biological and therapeutic relevance of nonreplicative DNA polymerases to cancer.

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Jason L Parsons

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Nils H Nicolay

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Ricky A Sharma

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P2860

Altered hematopoiesis in mice lacking DNA polymerase mu is due to inefficient double-strand break repair

hRAD30 mutations in the variant form of xeroderma pigmentosum

Long patch base excision repair with purified human proteins. DNA ligase I as patch size mediator for DNA polymerases delta and epsilon

Eukaryotic DNA Polymerases

Two novel human and mouse DNA polymerases of the polX family

POLQ (Pol theta), a DNA polymerase and DNA-dependent ATPase in human cells

Crystal structure of human REV7 in complex with a human REV3 fragment and structural implication of the interaction between DNA polymerase zeta and REV1

Three DNA polymerases, recruited by different mechanisms, carry out NER repair synthesis in human cells

Human DNA polymerase iota protects cells against oxidative stress

Human DNA polymerase theta possesses 5'-dRP lyase activity and functions in single-nucleotide base excision repair in vitro

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851-873

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scholarly article

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10.1089/ARS.2011.4203

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8

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18

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2012-09-05T00:00:00Z

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22794079

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3557440

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