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Evaluation of Adverse Drug Properties with Cryopreserved Human Hepatocytes and the Integrated Discrete Multiple Organ Co-culture (IdMOC(TM)) SystemDrug transporters in tissues and cells relevant to sexual transmission of HIV: Implications for drug deliveryNeonatal Cholestasis - Differential Diagnoses, Current Diagnostic Procedures, and TreatmentMutations in the nuclear bile acid receptor FXR cause progressive familial intrahepatic cholestasisDetergent screening and purification of the human liver ABC transporters BSEP (ABCB11) and MDR3 (ABCB4) expressed in the yeast Pichia pastorisRe-sequencing data for refining candidate genes and polymorphisms in QTL regions affecting adiposity in chicken.Progressive familial intrahepatic cholestasis.ABCMdb reloaded: updates on mutations in ATP binding cassette proteins.Hepatobiliary quiz-10 (2014)Sodium-dependent bile salt transporters of the SLC10A transporter family: more than solute transporters.The feline bile salt export pump: a structural and functional comparison with canine and human Bsep/BSEPAnalysis of the Bile Salt Export Pump (ABCB11) Interactome Employing Complementary Approaches.A preliminary investigation on single nucleotide polymorphism rs2287622 of bile salt export pump gene in patients with chronic hepatitis C virus infection in Hunan, ChinaCritical Factors in the Assessment of Cholestatic Liver Injury In Vitro.CYP2E1-dependent elevation of serum cholesterol, triglycerides, and hepatic bile acids by isoniazid.Role of polymorphic bile salt export pump (BSEP, ABCB11) transporters in anti-tuberculosis drug-induced liver injury in a Chinese cohort.Biosynthesis and trafficking of the bile salt export pump, BSEP: therapeutic implications of BSEP mutations.Role of Inflammatory and Oxidative Stress, Cytochrome P450 2E1, and Bile Acid Disturbance in Rat Liver Injury Induced by Isoniazid and Lipopolysaccharide Cotreatment.The role of bile salt export pump gene repression in drug-induced cholestatic liver toxicity.Genetic and Proteomic characterization of Bile Salt Export Pump (BSEP) in Snake Liver.Emerging transporters of clinical importance: an update from the International Transporter Consortium.Hormonal regulation of hepatic drug biotransformation and transport systems.High-content analysis/screening for predictive toxicology: application to hepatotoxicity and genotoxicity.Biomarkers and human hepatocytes.Positron emission tomography diagnostic imaging in multidrug-resistant hepatocellular carcinoma: focus on 2-deoxy-2-(18F)Fluoro-D-Glucose.Effect of drug transporter pharmacogenetics on cholestasis.Autoimmune BSEP disease: disease recurrence after liver transplantation for progressive familial intrahepatic cholestasis.A novel mutation within a transmembrane helix of the bile salt export pump (BSEP, ABCB11) with delayed development of cirrhosis.Intestinal and hepatic drug transporters: pharmacokinetic, pathophysiological, and pharmacogenetic roles.Cholestatic liver (dys)function during sepsis and other critical illnesses.Recent advances in the exploration of the bile salt export pump (BSEP/ABCB11) function.Exon-skipping and mRNA decay in human liver tissue: molecular consequences of pathogenic bile salt export pump mutations.Bile salt export pump-reactive antibodies form a polyclonal, multi-inhibitory response in antibody-induced bile salt export pump deficiency.Partial external biliary diversion in bile salt export pump deficiency: Association between outcome and mutation.A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.History of hepatic bile formation: old problems, new approaches.Investigation of Glycochenodeoxycholate Sulfate and Chenodeoxycholate Glucuronide as Surrogate Endogenous Probes for Drug Interaction Studies of OATP1B1 and OATP1B3 in Healthy Japanese Volunteers.In Vitro Drug-Induced Liver Injury Prediction: Criteria Optimization of Efflux Transporter IC50 and Physicochemical Properties.High affinity anti-BSEP antibodies after liver transplantation for PFIC-2 - Successful treatment with immunoadsorption and B-cell depletion.Retargeting of bile salt export pump and favorable outcome in children with progressive familial intrahepatic cholestasis type 2.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
The bile salt export pump (BSEP) in health and disease.
@en
type
label
The bile salt export pump (BSEP) in health and disease.
@en
prefLabel
The bile salt export pump (BSEP) in health and disease.
@en
P2093
P1476
The bile salt export pump (BSEP) in health and disease.
@en
P2093
Carola Dröge
Jan Stindt
Katrin Weissenberger
Ralf Kubitz
P304
P356
10.1016/J.CLINRE.2012.06.006
P577
2012-07-12T00:00:00Z