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The evidence for natural therapeutics as potential anti-scarring agents in burn-related scarringIn vitro induction of erythrocyte phosphatidylserine translocation by the natural naphthoquinone shikonin.β, β-Dimethylacrylshikonin induces mitochondria-dependent apoptosis of human lung adenocarcinoma cells in vitro via p38 pathway activation.β-hydroxyisovaleryl-shikonin induces human cervical cancer cell apoptosis via PI3K/AKT/mTOR signalingShikonin Attenuates Concanavalin A-Induced Acute Liver Injury in Mice via Inhibition of the JNK PathwayThe protective effects of shikonin on hepatic ischemia/reperfusion injury are mediated by the activation of the PI3K/Akt pathway.Enhancement of NK cells proliferation and function by Shikonin.Synthesis and Evaluation of New Naphthalene and Naphthoquinone Derivatives as Anticancer Agents.One-pot synthesis of 1,4-dihydroxy-2-((E)-1-hydroxy-4-phenylbut-3-enyl)anthracene-9,10-diones as novel shikonin analogs and evaluation of their antiproliferative activities.Shikonin Derivative DMAKO-05 Inhibits Akt Signal Activation and Melanoma Proliferation.Shikonin inhibits invasiveness of osteosarcoma through MMP13 suppression.Shikonin selectively induces apoptosis in human prostate cancer cells through the endoplasmic reticulum stress and mitochondrial apoptotic pathway.A potent anticancer agent of shikonin derivative targeting tubulin.Design, synthesis, and biological evaluation of shikonin and alkannin derivatives as potential anticancer agents via a prodrug approach.Shikonin inhibits inflammation and chondrocyte apoptosis by regulation of the PI3K/Akt signaling pathway in a rat model of osteoarthritis.Antiviral activity of shikonin ester derivative PMM-034 against enterovirus 71 in vitro.Development of a novel hollow-fiber liquid-phase microextraction based on oil-in-salt and its comparison with conventional one.Inhibiting aerobic glycolysis suppresses renal interstitial fibroblast activation and renal fibrosis.Broad blocking of MDR efflux pumps by acetylshikonin and acetoxyisovalerylshikonin to generate hypersensitive phenotype of malignant carcinoma cells.Shikonin-mediated up-regulation of miR-34a and miR-202 inhibits retinoblastoma proliferation
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description
article científic
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article scientifique
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articol științific
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articolo scientifico
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artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
Shikonin and its derivatives: a patent review.
@en
type
label
Shikonin and its derivatives: a patent review.
@en
prefLabel
Shikonin and its derivatives: a patent review.
@en
P2093
P2860
P1476
Shikonin and its derivatives: a patent review.
@en
P2093
Rubing Wang
Runting Yin
Shaoshun Li
P2860
P304
P356
10.1517/13543776.2012.709237
P407
P577
2012-07-27T00:00:00Z