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Transcription Regulation of the Human Telomerase Reverse Transcriptase (hTERT) GeneRoles of telomeres and telomerase in cancer, and advances in telomerase-targeted therapiesIntegration of Telomere Length Dynamics into Systems Biology Framework: A ReviewEmerging therapeutic targets in esophageal adenocarcinomaVariations in telomere maintenance and the role of telomerase inhibition in gastrointestinal cancerSolution and Solid-State Analysis of Binding of 13-Substituted Berberine Analogues to Human Telomeric G-quadruplexesTelomerase as a Cancer Target. Development of New MoleculesNanomedicine strategies for sustained, controlled, and targeted treatment of cancer stem cells of the digestive systemImetelstat, a telomerase inhibitor, differentially affects normal and malignant megakaryopoiesis.Mutations in IDH1, IDH2, and in the TERT promoter define clinically distinct subgroups of adult malignant gliomasRHPS4 G-quadruplex ligand induces anti-proliferative effects in brain tumor cells.Telomere maintenance mechanisms in cancer: clinical implicationsEffects of mitochondrial translocation of telomerase on drug resistance in hepatocellular carcinoma cells.A preclinical mouse model of glioma with an alternative mechanism of telomere maintenance (ALT).Telomerase activated thymidine analogue pro-drug is a new molecule targeting hepatocellular carcinoma.Ret finger protein-like 3 promotes tumor cell growth by activating telomerase reverse transcriptase expression in human lung cancer cellsT-oligo as an anticancer agent in colorectal cancerTelomere length and telomerase activity in non-small cell lung cancer prognosis: clinical usefulness of a specific telomere statusTying up the Ends: Plasticity in the Recognition of Single-Stranded DNA at Telomeres.Knockdown of hTERT and Treatment with BIBR1532 Inhibit Cell Proliferation and Invasion in Endometrial Cancer Cells.MicroRNA-532 and microRNA-3064 inhibit cell proliferation and invasion by acting as direct regulators of human telomerase reverse transcriptase in ovarian cancer.The telomerase inhibitor imetelstat alone, and in combination with trastuzumab, decreases the cancer stem cell population and self-renewal of HER2+ breast cancer cellsMolecular recognition of a carboxy pyridostatin toward G-quadruplex structures: Why does it prefer RNA?Loss of ATRX and DAXX expression identifies poor prognosis for smooth muscle tumours of uncertain malignant potential and early stage uterine leiomyosarcomaCross-sectional Associations between Exposure to Persistent Organic Pollutants and Leukocyte Telomere Length among U.S. Adults in NHANES, 2001-2002Arsenic trioxide inhibits glioma cell growth through induction of telomerase displacement and telomere dysfunction.Mechanism of DNA damage responses induced by exposure to an oligonucleotide homologous to the telomere overhang in melanoma.PinX1 suppresses tumorigenesis by negatively regulating telomerase/telomeres in colorectal carcinoma cells and is a promising molecular marker for patient prognosis.TERT promoter mutations in bladder cancer affect patient survival and disease recurrence through modification by a common polymorphismPreparation of 6/8/11-Amino/Chloro-Oxoisoaporphine and Group-10 Metal Complexes and Evaluation of Their in Vitro and in Vivo Antitumor ActivityEpstein-Barr virus and telomerase: from cell immortalization to therapy.KLF4 downregulates hTERT expression and telomerase activity to inhibit lung carcinoma growth.Fundamental mechanisms of telomerase action in yeasts and mammals: understanding telomeres and telomerase in cancer cells.Quantum Dots-siRNA Nanoplexes for Gene Silencing in Central Nervous System Tumor Cells.Alternative lengthening of telomeres: remodeling the telomere architecture.Telomerase promoter mutations in cancer: an emerging molecular biomarker?Evolving understanding of the CLL genome.Targeting of histone deacetylases in brain tumors.T cell-based targeted immunotherapies for patients with multiple myeloma.Treating Cancer by Targeting Telomeres and Telomerase.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Novel anticancer therapeutics targeting telomerase.
@en
type
label
Novel anticancer therapeutics targeting telomerase.
@en
prefLabel
Novel anticancer therapeutics targeting telomerase.
@en
P1476
Novel anticancer therapeutics targeting telomerase.
@en
P2093
Maria Ruden
Neelu Puri
P304
P356
10.1016/J.CTRV.2012.06.007
P577
2012-07-26T00:00:00Z