A prescription for 'stress'--the role of Hsp90 in genome stability and cellular adaptation
about
Selective targeting of the stress chaperome as a therapeutic strategyLPS induces pp60c-src-mediated tyrosine phosphorylation of Hsp90 in lung vascular endothelial cells and mouse lung.Antistress Effects of the Ethanolic Extract from Cymbopogon schoenanthus Growing Wild in TunisiaSmall molecule inhibitor screening identifified HSP90 inhibitor 17-AAG as potential therapeutic agent for gallbladder cancer.HSP90 regulates DNA repair via the interaction between XRCC1 and DNA polymerase βHeat shock factor 1 confers resistance to Hsp90 inhibitors through p62/SQSTM1 expression and promotion of autophagic fluxp53 protects against LPS-induced lung endothelial barrier dysfunction.Identification of the interactors of human nibrin (NBN) and of its 26 kDa and 70 kDa fragments arising from the NBN 657del5 founder mutation.Polypeptide-based nanogels co-encapsulating a synergistic combination of doxorubicin with 17-AAG show potent anti-tumor activity in ErbB2-driven breast cancer models.Potent antitrypanosomal activities of heat shock protein 90 inhibitors in vitro and in vivo.Ploidy plasticity: a rapid and reversible strategy for adaptation to stress.Heat Shock Protein 90 Regulates Subcellular Localization of Smads in Mv1Lu Cells.Causes and consequences of protein folding stress in aneuploid cells.Antioxidant responses and deregulation of epigenetic writers and erasers link oxidative stress and DNA methylation in bovine blastocysts.Proteome Stability as a Key Factor of Genome Integrity.Cdc7-Dbf4-mediated phosphorylation of HSP90-S164 stabilizes HSP90-HCLK2-MRN complex to enhance ATR/ATM signaling that overcomes replication stress in cancer.Molecular Genetic Analysis of Human Endometrial Mesenchymal Stem Cells That Survived Sublethal Heat Shock.
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P2860
A prescription for 'stress'--the role of Hsp90 in genome stability and cellular adaptation
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
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artikull shkencor
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artículo científico
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name
A prescription for 'stress'--t ...... bility and cellular adaptation
@en
type
label
A prescription for 'stress'--t ...... bility and cellular adaptation
@en
prefLabel
A prescription for 'stress'--t ...... bility and cellular adaptation
@en
P2860
P1476
A prescription for 'stress'--t ...... bility and cellular adaptation
@en
P2093
Kenneth B Kaplan
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P304
P356
10.1016/J.TCB.2012.08.006
P577
2012-09-04T00:00:00Z