Peroxiredoxins, gerontogenes linking aging to genome instability and cancer.
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The good and the bad of being connected: the integrons of agingThe Roles of Peroxiredoxin and Thioredoxin in Hydrogen Peroxide Sensing and in Signal TransductionPeroxiredoxins: guardians against oxidative stress and modulators of peroxide signalingA primer on peroxiredoxin biochemistryLight-sensing via hydrogen peroxide and a peroxiredoxin.Tubulin Beta-3 Chain as a New Candidate Protein Biomarker of Human Skin Aging: A Preliminary Study.Genome-wide screening identifies new genes required for stress-induced phase 2 detoxification gene expression in animals.Loss of APD1 in yeast confers hydroxyurea sensitivity suppressed by Yap1p transcription factorTargeting catalase but not peroxiredoxins enhances arsenic trioxide-induced apoptosis in K562 cells.Sestrin 2 protein regulates platelet-derived growth factor receptor β (Pdgfrβ) expression by modulating proteasomal and Nrf2 transcription factor functions.Oxidative stress in fungi: its function in signal transduction, interaction with plant hosts, and lignocellulose degradationOxidative stress in aging human skin.Adenanthin targets peroxiredoxin I/II to kill hepatocellular carcinoma cells.Oxidative Stress Promotes Peroxiredoxin Hyperoxidation and Attenuates Pro-survival Signaling in Aging Chondrocytes.Increasing extracellular H2O2 produces a bi-phasic response in intracellular H2O2, with peroxiredoxin hyperoxidation only triggered once the cellular H2O2-buffering capacity is overwhelmed.Proteomic analysis of non-small cell lung cancer tissue interstitial fluids.MnTnBuOE-2-PyP protects normal colorectal fibroblasts from radiation damage and simultaneously enhances radio/chemotherapeutic killing of colorectal cancer cellsTransition steps in peroxide reduction and a molecular switch for peroxide robustness of prokaryotic peroxiredoxins.Happily (n)ever after: Aging in the context of oxidative stress, proteostasis loss and cellular senescence.Sestrins: novel antioxidant and AMPK-modulating functions regulated by exercise?Linking Peroxiredoxin and Vacuolar-ATPase Functions in Calorie Restriction-Mediated Life Span Extension.Senescent remodeling of the innate and adaptive immune system in the elderly men with prostate cancer.Targeted Annotation of S-Sulfonylated Peptides by Selective Infrared Multiphoton Dissociation Mass Spectrometry.SIRT2 Deacetylates and Inhibits the Peroxidase Activity of Peroxiredoxin-1 to Sensitize Breast Cancer Cells to Oxidant Stress-Inducing Agents.Proteomic analysis identifies proteins associated with curcumin-enhancing efficacy of irinotecan-induced apoptosis of colorectal cancer LOVO cellMorphological changes and altered expression of antioxidant proteins in a heterozygous dynein mutant; a mouse model of spinal muscular atrophy.Chaperones: needed for both the good times and the bad times.Physiological relevance of plant 2-Cys peroxiredoxin overoxidation level and oligomerization status.A peroxiredoxin promotes H2O2 signaling and oxidative stress resistance by oxidizing a thioredoxin family protein.Active-site plasticity revealed in the asymmetric dimer of AnPrx6 the 1-Cys peroxiredoxin and molecular chaperone from Anabaena sp. PCC 7210.Redox-sensitive alteration of replisome architecture safeguards genome integrity.Proteome Stability as a Key Factor of Genome Integrity.RKIP and peroxiredoxin 2 expression predicts the proliferative potential of gastric cancer stem cells.Peroxiredoxin-1 promotes cell proliferation and metastasis through enhancing Akt/mTOR in human osteosarcoma cells.Metal-induced self-assembly of peroxiredoxin as a tool for sorting ultrasmall gold nanoparticles into one-dimensional clustersDownregulation of peroxiredoxin II suppresses the proliferation and metastasis of gastric cancer cellsSpecies comparison of liver proteomes reveals links to naked mole-rat longevity and human aging
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P2860
Peroxiredoxins, gerontogenes linking aging to genome instability and cancer.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
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artikull shkencor
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artículo científico
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name
Peroxiredoxins, gerontogenes linking aging to genome instability and cancer.
@en
type
label
Peroxiredoxins, gerontogenes linking aging to genome instability and cancer.
@en
prefLabel
Peroxiredoxins, gerontogenes linking aging to genome instability and cancer.
@en
P2860
P356
P1433
P1476
Peroxiredoxins, gerontogenes linking aging to genome instability and cancer
@en
P2093
Thomas Nyström
P2860
P304
P356
10.1101/GAD.200006.112
P577
2012-09-01T00:00:00Z