Recent advances in technology supporting biopharmaceutical production from mammalian cells.
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A Single-use Strategy to Enable Manufacturing of Affordable BiologicsRecent advances in mammalian protein productionGlycoengineering of pertuzumab and its impact on the pharmacokinetic/pharmacodynamic properties.Glycosylation-related genes in NS0 cells are insensitive to moderately elevated ammonium concentrationsNon-stationary 13C metabolic flux analysis of Chinese hamster ovary cells in batch culture using extracellular labeling highlights metabolic reversibility and compartmentation.5' and 3' Untranslated Regions Strongly Enhance Performance of Geminiviral Replicons in Nicotiana benthamiana Leaves.Improved antibody production in Chinese hamster ovary cells by ATF4 overexpressionGeneOptimizer program-assisted cDNA reengineering enhances sRAGE autologous expression in Chinese hamster ovary cells.Microbials for the production of monoclonal antibodies and antibody fragments.Innovative approach for improved rFVIII concentrate.Turoctocog alfa (NovoEight®)--from design to clinical proof of concept.Protein folding and secretion: mechanistic insights advancing recombinant protein production in S. cerevisiae.Tailoring recombinant protein quality by rational media design.Sophisticated Cloning, Fermentation, and Purification Technologies for an Enhanced Therapeutic Protein Production: A Review.The 'Omics Revolution in CHO Biology: Roadmap to Improved CHO Productivity.Low glucose concentrations within typical industrial operating conditions have minimal effect on the transcriptome of recombinant CHO cells.High-throughput screening and selection of mammalian cells for enhanced protein production.Overexpression of microRNAs enhances recombinant protein production in Chinese hamster ovary cells.Recent advances in (therapeutic protein) drug development.Glycoengineering of CHO Cells to Improve Product Quality.Robust factor selection in early cell culture process development for the production of a biosimilar monoclonal antibody.Development of adsorptive hybrid filters to enable two-step purification of biologics.Intrinsic fluorescence-based at situ soft sensor for monitoring monoclonal antibody aggregation.Efficient production of single-chain fragment variable-based N-terminal trimerbodies in Pichia pastoris.Improving recombinant protein production in the Chlamydomonas reinhardtii chloroplast using vivid Verde Fluorescent Protein as a reporterMain Quality Attributes of Monoclonal Antibodies and Effect of Cell Culture ComponentsGenetic analysis of heterogeneous sub-clones in recombinant Chinese hamster ovary cells.Development of a soft-sensor based on multi-wavelength fluorescence spectroscopy and a dynamic metabolic model for monitoring mammalian cell cultures.Sustaining an efficient and effective CHO cell line development platform by incorporation of 24-deep well plate screening and multivariate analysis.Improved fed-batch bioprocesses using chemically modified amino acids in concentrated feeds.Conserved microRNA function as a basis for Chinese hamster ovary cell engineering.Development of a 3-step straight-through purification strategy combining membrane adsorbers and resins.Identifying HIPK1 as Target of miR-22-3p Enhancing Recombinant Protein Production From HEK 293 Cell by Using Microarray and HTP siRNA Screen.miR-CATCH Identifies Biologically Active miRNA Regulators of the Pro-Survival Gene XIAP, in Chinese Hamster Ovary Cells.Trends in Upstream and Downstream Process Development for Antibody Manufacturing.Parallel experimental design and multivariate analysis provides efficient screening of cell culture media supplements to improve biosimilar product quality.Fluorescence-based soft sensor for at situ monitoring of Chinese hamster ovary cell cultures.The bioactivity and fractionation of peptide hydrolysates in cultures of CHO cells.One plus one makes three: adding value by co-transfection of anti-apoptotic genes during transient gene expression
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P2860
Recent advances in technology supporting biopharmaceutical production from mammalian cells.
description
article científic
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article scientifique
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articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
Recent advances in technology ...... oduction from mammalian cells.
@en
type
label
Recent advances in technology ...... oduction from mammalian cells.
@en
prefLabel
Recent advances in technology ...... oduction from mammalian cells.
@en
P2860
P1476
Recent advances in technology ...... oduction from mammalian cells.
@en
P2093
A Meneses-Acosta
P2860
P2888
P304
P356
10.1007/S00253-012-4451-Z
P407
P577
2012-10-05T00:00:00Z
P5875
P6179
1034256811