Signalling danger: endoplasmic reticulum stress and the unfolded protein response in pancreatic islet inflammation.
about
Where, How, and When: Positioning Posttranslational Modification Within Type 1 Diabetes PathogenesisMolecular Events Linking Oxidative Stress and Inflammation to Insulin Resistance and β-Cell DysfunctionThe impact of anti-inflammatory cytokines on the pancreatic β-cellIslet inflammation: a unifying target for diabetes treatment?Islet inflammation in plain sightChaperones ameliorate beta cell dysfunction associated with human islet amyloid polypeptide overexpressionJagn1 Is Induced in Response to ER Stress and Regulates Proinsulin BiosynthesisEndoplasmic reticulum stress sensitizes pancreatic beta cells to interleukin-1β-induced apoptosis via Bim/A1 imbalanceType 1 diabetes mellitus.A combined "omics" approach identifies N-Myc interactor as a novel cytokine-induced regulator of IRE1 protein and c-Jun N-terminal kinase in pancreatic beta cells.Restoration of the unfolded protein response in pancreatic β cells protects mice against type 1 diabetes.SUMOylation protects against IL-1β-induced apoptosis in INS-1 832/13 cells and human islets.Glucotoxic and diabetic conditions induce caspase 6-mediated degradation of nuclear lamin A in human islets, rodent islets and INS-1 832/13 cellsPancreatic and duodenal homeobox protein 1 (Pdx-1) maintains endoplasmic reticulum calcium levels through transcriptional regulation of sarco-endoplasmic reticulum calcium ATPase 2b (SERCA2b) in the islet β cell.Region-specific vulnerability to endoplasmic reticulum stress-induced neuronal death in rat brain after status epilepticus.MicroRNAs miR-23a-3p, miR-23b-3p, and miR-149-5p Regulate the Expression of Proapoptotic BH3-Only Proteins DP5 and PUMA in Human Pancreatic β-Cells.Cellular stress and innate inflammation in organ-specific autoimmunity: lessons learned from vitiligo.ER stress and the decline and fall of pancreatic beta cells in type 1 diabetes.Ubiquitin D Regulates IRE1α/c-Jun N-terminal Kinase (JNK) Protein-dependent Apoptosis in Pancreatic Beta CellsPhospho-BAD BH3 mimicry protects β cells and restores functional β cell mass in diabetes.Mouse models of diabetic neuropathy.Innate immune mechanisms in vitiligo: danger from within.Novel approaches to drug discovery for the treatment of type 2 diabetes.The Role of Damage-Associated Molecular Patterns (DAMPs) in Human Diseases: Part II: DAMPs as diagnostics, prognostics and therapeutics in clinical medicine.Antidiabetic Effects of Simple Phenolic Acids: A Comprehensive Review.Neuron-enriched RNA-binding Proteins Regulate Pancreatic Beta Cell Function and Survival.Islet inflammation in type 2 diabetes.Sensitivity profile of the human EndoC-βH1 beta cell line to proinflammatory cytokines.Lipid signaling and lipotoxicity in metaflammation: indications for metabolic disease pathogenesis and treatment.Biomarkers of β-Cell Stress and Death in Type 1 Diabetes.Elevations in the Fasting Serum Proinsulin-to-C-Peptide Ratio Precede the Onset of Type 1 Diabetes.IL-13 improves beta-cell survival and protects against IL-1beta-induced beta-cell death.TM7SF3, a novel p53-regulated homeostatic factor, attenuates cellular stress and the subsequent induction of the unfolded protein response.Signal transducer and activator of transcription 3 regulates CCAAT-enhancer-binding homologous protein expression in osteoblasts through upregulation of microRNA-205.Type I Interferon Is a Catastrophic Feature of the Diabetic Islet MicroenvironmentIL-17A increases the expression of proinflammatory chemokines in human pancreatic islets.The Role of Oxidative Stress, Mitochondrial Function, and Autophagy in Diabetic Polyneuropathy.Redox-Sensitive Innate Immune Pathways During Macrophage Activation in Type 1 Diabetes.Overexpression of sphingosine-1-phosphate lyase protects insulin-secreting cells against cytokine toxicity.Type 2 diabetes mellitus--an autoimmune disease?
P2860
Q26750714-63B39ED0-980D-43E8-A4AB-EEE0E4A433A0Q26800081-5D796CF2-242B-4673-B16A-1804FC2081E0Q26822824-94E84AF4-1227-4AD1-8269-52C5516DC3B5Q26860847-4459F140-78D7-47C3-A09F-316E4150CB50Q27012796-1E639D48-FF10-4CCE-AF54-D9B339E7E19FQ28540631-6BF98CEF-7160-4FD4-A7C3-921FA74BEDC2Q28566751-FA6802BB-B070-496D-A24F-38C98F9825D0Q28574313-21EEED96-BFC7-4AEB-AE1C-58EFC8452ECBQ30235021-8F1FDD9A-2CC0-4318-A130-C5D14A0E6926Q33947078-F4064075-C5C7-4A37-B1C9-E67EA46A58B4Q34213205-38C2AE54-2530-4C62-8418-A77A6E0415D6Q34356005-FFA8B8DF-9DBE-4BA7-AF59-1511ADDA7096Q34476251-B6125377-C0B5-4FD9-BEC2-7B207CA09B88Q34552701-549FA34C-5555-4961-90D4-11994BE45203Q35057707-9135952F-CD28-49CD-ADFA-47B01EE4C151Q36163240-1E2F9D1B-4CA8-42E0-B94F-073828A046B0Q36389114-C5D099EB-656A-4A4B-B8F5-143D9DEF3BDEQ36986979-20C48D9C-9E14-4513-825D-3302D536D562Q37065973-1C64C6A5-7860-4AC9-A1EA-365B0271D639Q37189580-0CEB5E4C-C761-452F-8652-2D0C5266FD4BQ37655239-2141B2F7-DCCB-428A-AD87-5B2ECF2962F2Q38163168-CEECEFEA-8214-42A8-931F-81351C5FE9DAQ38233063-B3343F2C-9EF6-4D7A-8F18-C0DB771A92A4Q38519934-23B64879-D54A-4E8C-AFE1-F877300D123AQ38658576-F1839762-EAEB-4B53-BD63-2466E2B62358Q38721830-44E92490-71DB-49E6-A701-00FD4AB79346Q38740642-8D9EA3DC-128F-48FC-9884-19041E9E02B8Q38755624-8ABA60B6-700A-47E3-9C44-D2E38B486896Q38872713-C2784CFF-DBBF-4813-BC17-486EB4A7ED91Q38931848-78A0E7D3-A20F-4457-9EFA-81157A1E5427Q39626208-21B7FD90-00EF-4A10-9BB4-C878D2AF3916Q39973592-D8F15CB7-65E3-49B3-8FB4-B722D30DA22DQ40036341-FCB11F76-82FF-479B-8B3D-FB2F8952A8C3Q41554003-8C24CA65-056C-4A21-898B-389FFEC03DC6Q41672962-4C65B304-2FBB-4E90-AF92-671540C42A6DQ45344831-C02EFC60-F6A4-42DB-8153-E416EE06A1DBQ46248218-64F15902-DA65-4604-9A65-A33319576EC7Q46284091-DFA6BDCB-AA19-46DB-9905-FA990A2BC1ECQ46291793-C852FA3D-FD88-4BDF-8CC4-F7504239DC16Q46799317-8BB050D7-43A6-46FD-AE41-CCB914B7FF87
P2860
Signalling danger: endoplasmic reticulum stress and the unfolded protein response in pancreatic islet inflammation.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Signalling danger: endoplasmic ...... pancreatic islet inflammation.
@en
type
label
Signalling danger: endoplasmic ...... pancreatic islet inflammation.
@en
prefLabel
Signalling danger: endoplasmic ...... pancreatic islet inflammation.
@en
P2093
P2860
P1433
P1476
Signalling danger: endoplasmic ...... pancreatic islet inflammation.
@en
P2093
P2860
P2888
P304
P356
10.1007/S00125-012-2762-3
P577
2012-11-07T00:00:00Z
P5875
P6179
1027958834