about
Neddylation and deneddylation in cardiac biologyTargeting protein neddylation with an NEDD8-activating enzyme inhibitor MLN4924 induced apoptosis or senescence in human lymphoma cells.Chemical approaches to targeted protein degradation through modulation of the ubiquitin-proteasome pathwayMLN4924 induces Noxa upregulation in acute myelogenous leukemia and synergizes with Bcl-2 inhibitors.Posttranslational modifications of lysine and evolving role in heart pathologies-recent developments.The NEDD8 inhibitor MLN4924 increases the size of the nucleolus and activates p53 through the ribosomal-Mdm2 pathway.Expression of neddylation-related proteins in melanoma cell lines and the effect of neddylation on melanoma proliferation.Role of novel histone modifications in cancer.
P2860
Q34987403-79C2EF21-EBFE-43DA-A416-BB343DB85145Q36215406-44698DDC-6596-4C90-8D04-F5CA2E0F92D6Q36309724-E10E1CEC-63BD-48CA-9A51-BE3F6DAEA3FBQ36751575-30E1CB35-1586-47E5-A10B-D8BD1130434FQ38272115-F744D56A-2B63-4972-9ABD-9CC0BF1C70F3Q38888153-1F564093-7588-44C4-83B6-EEE837961BB1Q38933296-CA96B048-DC87-43A4-9623-17F92BD0272DQ52655031-B78CD822-75E2-416A-8A62-9D80F55C46E8
P2860
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
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2012年學術文章
@zh-hant
name
Targeting neddylation in cancer therapy.
@en
type
label
Targeting neddylation in cancer therapy.
@en
prefLabel
Targeting neddylation in cancer therapy.
@en
P2093
P2860
P356
P1433
P1476
Targeting neddylation in cancer therapy.
@en
P2093
Akhona Vava
Georgia Schäfer
Kristal Duncan
Luiz F Zerbini
M Iqbal Parker
P2860
P304
P356
10.2217/FON.12.131
P407
P577
2012-11-01T00:00:00Z