Context-dependent multifunctionality of galectin-1: a challenge for defining the lectin as therapeutic target.
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Fine-tuning of prototype chicken galectins: structure of CG-2 and structure-activity correlationsNatural single amino acid polymorphism (F19Y) in human galectin-8: detection of structural alterations and increased growth-regulatory activity on tumor cellsGalectin fingerprinting in naso-sinusal diseases.Pharmacological activation of estrogen receptors-α and -β differentially modulates keratinocyte differentiation with functional impact on wound healingEosinophils, galectins, and a reason to breathe.The third dimension of reading the sugar code by lectins: design of glycoclusters with cyclic scaffolds as tools with the aim to define correlations between spatial presentation and activity.Introduction to glycopathology: the concept, the tools and the perspectivesGalectin-1 Couples Glycobiology to Inflammation in Osteoarthritis through the Activation of an NF-κB-Regulated Gene Network.Conformational selection in glycomimetics: human galectin-1 only recognizes syn-Ψ-type conformations of β-1,3-linked lactose and its C-glycosyl derivative.Lectins: getting familiar with translators of the sugar code.Galectin-1 inhibitors and their potential therapeutic applications: a patent review.Sweet complementarity: the functional pairing of glycans with lectins.Galectins: their network and roles in immunity/tumor growth control.Binding of polysaccharides to human galectin-3 at a noncanonical site in its carbohydrate recognition domain.Merging carbohydrate chemistry with lectin histochemistry to study inhibition of lectin binding by glycoclusters in the natural tissue context.Regulatory Impact of Amniotic Membrane Transplantation on Presence of Adhesion/Growth-Regulatory Galectins-1 and -7 in Corneal Explants from Acanthamoeba Keratitis Patients: Clinical Note.Structural significance of galectin design: impairment of homodimer stability by linker insertion and partial reversion by ligand presence.Combination of galectin-3, CK19 and HBME-1 immunostaining improves the diagnosis of thyroid cancer.Galectin-1 is a diagnostic marker involved in thyroid cancer progression.Synthetic polyamine BPA-C8 inhibits TGF-β1-mediated conversion of human dermal fibroblast to myofibroblasts and establishment of galectin-1-rich extracellular matrix in vitro.Delineating binding modes of Gal/GalNAc and structural elements of the molecular recognition of tumor-associated mucin glycopeptides by the human macrophage galactose-type lectin.Novel polysaccharide binding to the N-terminal tail of galectin-3 is likely modulated by proline isomerization.Analyzing epigenetic control of galectin expression indicates silencing of galectin-12 by promoter methylation in colorectal cancer.Galectin-1 from conditioned medium of three-dimensional culture of adipose-derived stem cells accelerates migration and proliferation of human keratinocytes and fibroblasts.Galectin-3: One Molecule for an Alphabet of Diseases, from A to Z.Network monitoring of adhesion/growth-regulatory galectins: localization of the five canonical chicken proteins in embryonic and maturing bone and cartilage and their introduction as histochemical tools.Copy-number variation of functional galectin genes: studying animal galectin-7 (p53-induced gene 1 in man) and tandem-repeat-type galectins-4 and -9.Exploring the Structural Space of the Galectin-1-Ligand Interaction.Teaming up synthetic chemistry and histochemistry for activity screening in galectin-directed inhibitor design.Human osteoarthritic knee cartilage: fingerprinting of adhesion/growth-regulatory galectins in vitro and in situ indicates differential upregulation in severe degeneration
P2860
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P2860
Context-dependent multifunctionality of galectin-1: a challenge for defining the lectin as therapeutic target.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
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artículo científico
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name
Context-dependent multifunctio ...... lectin as therapeutic target.
@en
type
label
Context-dependent multifunctio ...... lectin as therapeutic target.
@en
prefLabel
Context-dependent multifunctio ...... lectin as therapeutic target.
@en
P2093
P2860
P1476
Context-dependent multifunctio ...... lectin as therapeutic target.
@en
P2093
Hans-Joachim Gabius
Herbert Kaltner
Jürgen Kopitz
Karel Smetana
Sabine André
P2860
P304
P356
10.1517/14728222.2013.750651
P407
P577
2013-01-06T00:00:00Z